Psychological Medicine,
Год журнала:
2023,
Номер
53(16), С. 7874 - 7882
Опубликована: Июль 24, 2023
Abstract
Background
Older
brain
age
–
as
estimated
from
structural
MRI
data
is
known
to
be
associated
with
detrimental
mental
and
physical
health
outcomes
in
older
adults.
Social
isolation,
which
has
similar
effects
on
health,
may
accelerated
aging
though
little
about
how
different
trajectories
of
social
isolation
across
the
life
course
moderate
this
association.
We
examined
associations
between
5
38
assessed
at
45.
Methods
previously
created
a
typology
based
onset
during
persistence
into
adulthood,
using
group-based
trajectory
analysis
longitudinal
New
Zealand
birth
cohort.
The
comprises
four
groups:
‘never-isolated’,
‘adult-only’,
‘child-only’,
persistent
‘child-adult’
isolation.
A
gap
estimate
(brainAGE)
difference
predicted
date
chronological
was
derived
undertook
analyses
brainAGE
group
predictor,
adjusting
for
sex,
family
socio-economic
status,
range
familial
child-behavioral
factors.
Results
mid-adulthood
after
adjustment
child
confounders,
particularly
‘adult-only’
compared
‘never-isolated’
group.
Conclusions
Although
our
findings
are
associational,
they
indicate
that
preventing
mid-adulthood,
help
avert
negative
later
life.
Trends in Cognitive Sciences,
Год журнала:
2023,
Номер
27(10), С. 901 - 915
Опубликована: Авг. 8, 2023
Modifiable
risk
and
protective
factors
for
boosting
brain
cognitive
development
preventing
neurodegeneration
decline
are
embraced
in
neuroimaging
studies.
We
call
sobriety
regarding
the
timing
quantity
of
such
influences
on
cognition.
Individual
differences
level
cognition,
many
which
present
already
at
birth
early
development,
appear
stable,
larger,
more
pervasive
than
change
across
lifespan.
Incorporating
early-life
factors,
including
genetics,
investigating
both
will
reduce
ascribing
undue
importance
causality
to
proximate
adulthood
older
age.
This
has
implications
mechanistic
understanding
prevention.
Current Directions in Psychological Science,
Год журнала:
2023,
Номер
32(3), С. 220 - 227
Опубликована: Март 21, 2023
Executive
function
(EF)
skills,
including
working
memory,
inhibition,
and
cognitive
flexibility,
form
the
neurocognitive
basis
for
conscious,
goal-directed
behavior
self-control.
Young
children
are
notoriously
deficient
in
such
but
EF
improves
most
rapidly
preschool
period.
Individual
differences
predictive
of
a
host
important
life
outcomes,
recent
advances
measurement
intervention
promising.
Caregivers
play
key
role
development
EF,
particularly
with
respect
to
supporting
child’s
autonomy.
I
take
closer
look
at
agency
discuss
theoretical
empirical
support
notion
that
giving
sense
choice
how
act,
think,
feel
is
essential
healthy
skill
early
childhood.
Journal of Personality and Social Psychology,
Год журнала:
2023,
Номер
125(6), С. 1495 - 1518
Опубликована: Июнь 29, 2023
The
Big
Five
personality
traits
predict
many
important
life
outcomes.
These
traits,
although
relatively
stable,
are
also
open
to
change
across
time.
However,
whether
these
changes
likewise
a
wide
range
of
outcomes
has
yet
be
rigorously
tested.
This
implications
for
the
types
processes
linking
trait
levels
and
with
future
outcomes:
distal,
cumulative
versus
more
immediate,
proximal
processes,
respectively.
present
study
used
seven
longitudinal
data
sets
(N
=
81,980)
comprehensively
examine
unique
relationship
that
in
have
static
numerous
domains
health,
education,
career,
finance,
relationships,
civic
engagement.
Meta-analytic
estimates
were
calculated
study-level
variables
examined
as
potential
moderators
pooled
effects.
Results
indicated
sometimes
prospectively
related
outcomes-such
health
status,
degree
attainment,
unemployment,
volunteering-above
beyond
associations
due
levels.
Moreover,
frequently
predicted
outcomes,
new
emerging
well
(e.g.,
marriage,
divorce).
Across
all
meta-analytic
models,
magnitude
effects
was
never
larger
than
there
fewer
associations.
Study-level
average
age,
number
waves,
internal
consistency
estimates)
rarely
associated
Our
suggests
can
play
valuable
role
one's
development
highlights
both
matter
some
trait-outcome
(PsycInfo
Database
Record
(c)
2023
APA,
rights
reserved).
Clinical Epigenetics,
Год журнала:
2024,
Номер
16(1)
Опубликована: Фев. 8, 2024
Abstract
Self-control
is
a
personality
dimension
that
associated
with
better
physical
health
and
longer
lifespan.
Here,
we
examined
(1)
whether
self-control
buccal
saliva
DNA-methylation
(DNAm)
measures
of
biological
aging
quantified
in
children,
adolescents,
adults,
(2)
measured
DNAm
self-reported
health.
Following
preregistered
analyses,
computed
two
advanced
age
(principal-component
PhenoAge
GrimAge
Acceleration)
measure
pace
(DunedinPACE)
samples
from
the
German
Socioeconomic
Panel
Study
(SOEP-G[ene],
n
=
1058,
range
0–72,
M
42.65)
Texas
Twin
Project
(TTP,
1327,
8–20,
13.50).
We
found
lower
was
older
adults
(PhenoAge
Acceleration
β
−
.34,
[−
.51,
.17],
p
<
.001;
.49,
.19],
.001),
but
not
young
adolescents
or
children.
These
associations
remained
statistically
robust
even
after
correcting
for
possible
confounders
such
as
socioeconomic
contexts,
BMI,
genetic
correlates
low
self-control.
Moreover,
faster
were
disease
Acceleration:
.13
[.06,
.19
[.12,
.26],
DunedinPACE:
.09
[.02,
.01).
However,
effect
sizes
weaker
than
observations
blood,
suggesting
customization
to
tissues
may
be
necessary.
Our
findings
are
consistent
hypothesis
via
pathways
accelerate
adults.
Developmental Psychology,
Год журнала:
2023,
Номер
59(8), С. 1389 - 1406
Опубликована: Июнь 5, 2023
This
study
is
a
conceptual
replication
of
widely
cited
by
Moffitt
et
al.
(2011)
which
found
that
attention
and
behavior
problems
in
childhood
(a
composite
impulsive
hyperactive,
inattentive,
impulsive-aggressive
behaviors
labeled
"self-control")
predicted
adult
financial
status,
health,
criminal
activity.
Using
data
from
longitudinal
cohort
studies
the
United
States
(n
=
1,168)
Kingdom
(
Neurobiology of Stress,
Год журнала:
2024,
Номер
31, С. 100652 - 100652
Опубликована: Май 31, 2024
Adverse
early-life
experiences
(ELA)
affect
a
majority
of
the
world's
children.
Whereas
enduring
impact
ELA
on
cognitive
and
emotional
health
is
established,
there
are
no
tools
to
predict
vulnerability
consequences
in
an
individual
child.
Epigenetic
markers
including
peripheral-cell
DNA-methylation
profiles
may
encode
provide
predictive
outcome
markers,
yet
interindividual
variance
human
genome
rapid
changes
DNA
methylation
childhood
pose
significant
challenges.
Hoping
mitigate
these
challenges
we
examined
relation
several
dimensions
using
within-subject
longitudinal
design
high
methylation-change
threshold.
was
analyzed
buccal
swab
/
saliva
samples
collected
twice
(neonatally
at
12
months)
110
infants.
We
identified
CpGs
differentially
methylated
across
time
for
each
child
determined
whether
they
associated
with
indicators
executive
function
age
5.
assessed
sex
differences
derived
sex-dependent
'impact
score'
based
sites
that
most
contributed
changes.
Changes
between
two
reflected
age-related
trends
correlated
years
later.
Among
tested
life
factors
income
needs
ratios,
maternal
sensitivity,
body
mass
index
infant
sex,
unpredictability
parental
household
signals
strongest
predictor
function.
In
girls,
interacted
presage
Thus,
longitudinal,
signature
potential
marker
outcome.
