Social isolation from childhood to mid-adulthood: is there an association with older brain age? DOI Creative Commons
Roy Lay‐Yee, Ahmad R. Hariri, Annchen R. Knodt

et al.

Psychological Medicine, Journal Year: 2023, Volume and Issue: 53(16), P. 7874 - 7882

Published: July 24, 2023

Abstract Background Older brain age – as estimated from structural MRI data is known to be associated with detrimental mental and physical health outcomes in older adults. Social isolation, which has similar effects on health, may accelerated aging though little about how different trajectories of social isolation across the life course moderate this association. We examined associations between 5 38 assessed at 45. Methods previously created a typology based onset during persistence into adulthood, using group-based trajectory analysis longitudinal New Zealand birth cohort. The comprises four groups: ‘never-isolated’, ‘adult-only’, ‘child-only’, persistent ‘child-adult’ isolation. A gap estimate (brainAGE) difference predicted date chronological was derived undertook analyses brainAGE group predictor, adjusting for sex, family socio-economic status, range familial child-behavioral factors. Results mid-adulthood after adjustment child confounders, particularly ‘adult-only’ compared ‘never-isolated’ group. Conclusions Although our findings are associational, they indicate that preventing mid-adulthood, help avert negative later life.

Language: Английский

Timing of lifespan influences on brain and cognition DOI Creative Commons
Kristine B. Walhovd, Martin Lövdén, Anders M. Fjell

et al.

Trends in Cognitive Sciences, Journal Year: 2023, Volume and Issue: 27(10), P. 901 - 915

Published: Aug. 8, 2023

Modifiable risk and protective factors for boosting brain cognitive development preventing neurodegeneration decline are embraced in neuroimaging studies. We call sobriety regarding the timing quantity of such influences on cognition. Individual differences level cognition, many which present already at birth early development, appear stable, larger, more pervasive than change across lifespan. Incorporating early-life factors, including genetics, investigating both will reduce ascribing undue importance causality to proximate adulthood older age. This has implications mechanistic understanding prevention.

Language: Английский

Citations

59

Let Me Choose: The Role of Choice in the Development of Executive Function Skills DOI
Stephanie M. Carlson

Current Directions in Psychological Science, Journal Year: 2023, Volume and Issue: 32(3), P. 220 - 227

Published: March 21, 2023

Executive function (EF) skills, including working memory, inhibition, and cognitive flexibility, form the neurocognitive basis for conscious, goal-directed behavior self-control. Young children are notoriously deficient in such but EF improves most rapidly preschool period. Individual differences predictive of a host important life outcomes, recent advances measurement intervention promising. Caregivers play key role development EF, particularly with respect to supporting child’s autonomy. I take closer look at agency discuss theoretical empirical support notion that giving sense choice how act, think, feel is essential healthy skill early childhood.

Language: Английский

Citations

18

Do changes in personality predict life outcomes? DOI
Amanda Jo Wright,

Joshua J. Jackson

Journal of Personality and Social Psychology, Journal Year: 2023, Volume and Issue: 125(6), P. 1495 - 1518

Published: June 29, 2023

The Big Five personality traits predict many important life outcomes. These traits, although relatively stable, are also open to change across time. However, whether these changes likewise a wide range of outcomes has yet be rigorously tested. This implications for the types processes linking trait levels and with future outcomes: distal, cumulative versus more immediate, proximal processes, respectively. present study used seven longitudinal data sets (N = 81,980) comprehensively examine unique relationship that in have static numerous domains health, education, career, finance, relationships, civic engagement. Meta-analytic estimates were calculated study-level variables examined as potential moderators pooled effects. Results indicated sometimes prospectively related outcomes-such health status, degree attainment, unemployment, volunteering-above beyond associations due levels. Moreover, frequently predicted outcomes, new emerging well (e.g., marriage, divorce). Across all meta-analytic models, magnitude effects was never larger than there fewer associations. Study-level average age, number waves, internal consistency estimates) rarely associated Our suggests can play valuable role one's development highlights both matter some trait-outcome (PsycInfo Database Record (c) 2023 APA, rights reserved).

Language: Английский

Citations

17

Self-control is associated with health-relevant disparities in buccal DNA-methylation measures of biological aging in older adults DOI Creative Commons
Yayouk E. Willems, Abby J. deSteiguer, Peter T. Tanksley

et al.

Clinical Epigenetics, Journal Year: 2024, Volume and Issue: 16(1)

Published: Feb. 8, 2024

Abstract Self-control is a personality dimension that associated with better physical health and longer lifespan. Here, we examined (1) whether self-control buccal saliva DNA-methylation (DNAm) measures of biological aging quantified in children, adolescents, adults, (2) measured DNAm self-reported health. Following preregistered analyses, computed two advanced age (principal-component PhenoAge GrimAge Acceleration) measure pace (DunedinPACE) samples from the German Socioeconomic Panel Study (SOEP-G[ene], n = 1058, range 0–72, M 42.65) Texas Twin Project (TTP, 1327, 8–20, 13.50). We found lower was older adults (PhenoAge Acceleration β − .34, [− .51, .17], p < .001; .49, .19], .001), but not young adolescents or children. These associations remained statistically robust even after correcting for possible confounders such as socioeconomic contexts, BMI, genetic correlates low self-control. Moreover, faster were disease Acceleration: .13 [.06, .19 [.12, .26], DunedinPACE: .09 [.02, .01). However, effect sizes weaker than observations blood, suggesting customization to tissues may be necessary. Our findings are consistent hypothesis via pathways accelerate adults.

Language: Английский

Citations

7

Teaching self-regulation DOI
Daniel Schunk, Eva Berger, Henning Hermes

et al.

Nature Human Behaviour, Journal Year: 2022, Volume and Issue: 6(12), P. 1680 - 1690

Published: Oct. 13, 2022

Language: Английский

Citations

26

Attention and behavior problems in childhood predict adult financial status, health, and criminal activity: A conceptual replication and extension of Moffitt et al. (2011) using cohorts from the United States and the United Kingdom. DOI Creative Commons
Andrew E. Koepp, Tyler W. Watts, Elizabeth T. Gershoff

et al.

Developmental Psychology, Journal Year: 2023, Volume and Issue: 59(8), P. 1389 - 1406

Published: June 5, 2023

This study is a conceptual replication of widely cited by Moffitt et al. (2011) which found that attention and behavior problems in childhood (a composite impulsive hyperactive, inattentive, impulsive-aggressive behaviors labeled "self-control") predicted adult financial status, health, criminal activity. Using data from longitudinal cohort studies the United States (n = 1,168) Kingdom (

Language: Английский

Citations

15

Adult Attention-Deficit/Hyperactivity Disorder: a Narrative Review of Biological Mechanisms, Treatments, and Outcomes DOI
Antonio F. Pagán,

Yazmine P. Huizar,

Tucker R. Short

et al.

Current Neurology and Neuroscience Reports, Journal Year: 2023, Volume and Issue: 23(8), P. 451 - 460

Published: June 19, 2023

Language: Английский

Citations

14

Individual longitudinal changes in DNA-methylome identify signatures of early-life adversity and correlate with later outcome DOI Creative Commons
Annabel K. Short,

Ryan Weber,

Noriko Kamei

et al.

Neurobiology of Stress, Journal Year: 2024, Volume and Issue: 31, P. 100652 - 100652

Published: May 31, 2024

Adverse early-life experiences (ELA) affect a majority of the world's children. Whereas enduring impact ELA on cognitive and emotional health is established, there are no tools to predict vulnerability consequences in an individual child. Epigenetic markers including peripheral-cell DNA-methylation profiles may encode provide predictive outcome markers, yet interindividual variance human genome rapid changes DNA methylation childhood pose significant challenges. Hoping mitigate these challenges we examined relation several dimensions using within-subject longitudinal design high methylation-change threshold. was analyzed buccal swab / saliva samples collected twice (neonatally at 12 months) 110 infants. We identified CpGs differentially methylated across time for each child determined whether they associated with indicators executive function age 5. assessed sex differences derived sex-dependent 'impact score' based sites that most contributed changes. Changes between two reflected age-related trends correlated years later. Among tested life factors income needs ratios, maternal sensitivity, body mass index infant sex, unpredictability parental household signals strongest predictor function. In girls, interacted presage Thus, longitudinal, signature potential marker outcome.

Language: Английский

Citations

5

Mutual implications of procrastination research in adults and children for theory and intervention DOI
Caitlin E. V. Mahy, Yuko Munakata, Akira Miyake

et al.

Nature Reviews Psychology, Journal Year: 2024, Volume and Issue: 3(9), P. 589 - 605

Published: July 30, 2024

Language: Английский

Citations

5

Linking stressful life events and chronic inflammation using suPAR (soluble urokinase plasminogen activator receptor) DOI Creative Commons
Kyle J. Bourassa, Line Jee Hartmann Rasmussen, Andrea Danese

et al.

Brain Behavior and Immunity, Journal Year: 2021, Volume and Issue: 97, P. 79 - 88

Published: July 2, 2021

Language: Английский

Citations

32