Key enzymes involved in the utilization of fatty acids by Saccharomyces cerevisiae: a review

Frontiers in Microbiology, Год журнала: 2024, Номер 14

Опубликована: Янв. 11, 2024

is a eukaryotic organism with clear genetic background and mature gene operating system; in addition, it exhibits environmental tolerance. Therefore,

Язык: Английский

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Profiling the response of individual gut microbes to free fatty acids (FFAs) found in human milk

Journal of Functional Foods, Год журнала: 2025, Номер 125, С. 106664 - 106664

Опубликована: Янв. 8, 2025

Язык: Английский

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Long-chain unsaturated free fatty acids reduce the host cell invasion of Listeria monocytogenes outbreak strains

Frontiers in Cellular and Infection Microbiology, Год журнала: 2025, Номер 15

Опубликована: Фев. 28, 2025

The Gram-positive bacterium Listeria monocytogenes is a highly adaptable pathogen capable of causing severe foodborne infections, particularly in vulnerable populations. During infection, L. uses variety virulence factors to invade and multiply within host cells. transcriptional regulator PrfA controls the expression these essential for intracellular lifestyle . Long-chain unsaturated free fatty acids (FFAs) have long been recognized their antimicrobial activity were recently shown inhibit PrfA-dependent gene To date, anti-virulent activities FFAs primarily studied laboratory strains. However, fully evaluate potential as anti-infective agents, it assess effects long-chain on clinically relevant isolates, including outbreak strains associated with high-fat food products. Here, we demonstrate that five different isolates are sensitive FFAs. Furthermore, at subinhibitory concentrations, PrfA-regulated across all tested reduce invasive non-phagocytic These findings underscore developing new preventive strategies against infections.

Язык: Английский

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Long-chain fatty acids as nutrients for Gram-negative bacteria: stress, proliferation, and virulence

Current Opinion in Microbiology, Год журнала: 2025, Номер 85, С. 102609 - 102609

Опубликована: Апрель 18, 2025

Язык: Английский

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Immunology of the Bovine Mammary Gland

Veterinary Clinics of North America Food Animal Practice, Год журнала: 2025, Номер unknown

Опубликована: Апрель 1, 2025

Язык: Английский

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A unique combination of natural fatty acids from Hermetia illucens fly larvae fat effectively combats virulence factors and biofilms of MDR hypervirulent mucoviscus Klebsiella pneumoniae strains by increasing Lewis acid–base/van der Waals interactions in bacterial wall membranes

Frontiers in Cellular and Infection Microbiology, Год журнала: 2024, Номер 14

Опубликована: Июль 25, 2024

Hypervirulent

Язык: Английский

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Decoding Long-Chain Fatty Acid Ethyl Esters during the Distillation of Strong Aroma-Type Baijiu and Exploring the Adsorption Mechanism with Magnetic Nanoparticles

Journal of Agricultural and Food Chemistry, Год журнала: 2024, Номер unknown

Опубликована: Сен. 12, 2024

Simultaneous detection of the dynamic distribution long-chain fatty acid ethyl esters (LCFAEEs) during Baijiu distillation is crucial for optimizing its flavor and health attributes. In this study, we synthesized a simple, cost-effective Fe

Язык: Английский

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Recent advances in natural food preservatives: a sustainable solution for food safety and shelf life extension

Journal of Food Measurement & Characterization, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 12, 2024

Язык: Английский

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Investigation antibacterial application and mechanism of the cyclodextrin-metal-organic framework loaded with gold nanoparticle

CyTA - Journal of Food, Год журнала: 2024, Номер 22(1)

Опубликована: Апрель 5, 2024

The severe threat of microbial contamination to human life and health safety necessitates urgent research development antimicrobial materials capable inhibiting or eradicating pathogens. Cyclodextrin metal-organic framework (CD-MOF) was utilized as a carrier encapsulate gold nanoparticles (AuNPs), resulting in composite material (Au@CD-MOF) that exhibited remarkable antibacterial properties. study revealed Au@CD-MOF completely eradicated Staphylococcus aureus (S. aureus) Listeria monocytogenes (L. monocytogenes) at concentration approximately 1 × 105 CFU/mL after 48 h 36 h, respectively. Moreover, also demonstrated the complete elimination Escherichia coli O157:H7 (E. O157:H7), Pseudomonas aeruginosa PAO1 (P. PAO1), Salmonella typhimurium typhimurium) h. mechanism investigated using E. S. model organisms. findings disrupted integrity cell membranes diminished their potential, consequently impeding normal functions bacteria. Additionally, heightened permeability induced by resulted substantial leakage nucleic acids proteins, ultimately leading bacterial eradication.

Язык: Английский

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Long chain unsaturated fatty acids alter growth and reduce biofilm formation of Cronobacter sakazakii

Journal of Food Safety, Год журнала: 2024, Номер 44(3)

Опубликована: Май 2, 2024

Abstract Cronobacter sakazakii is a foodborne pathogen predominately transmitted through contaminated dried foods and affects populations including neonates, infants, the elderly. Following several recent outbreaks, it now notifiable infection in those under 12 months of age. Current control methods include strict manufacturing guidelines, with monitoring this genus legal requirement powdered infant formula production. Fatty acids have long been known as antimicrobials, long‐chain fatty increasingly identified agents that target virulence factors. This study gives insight into changes promoted by three unsaturated (oleic, linoleic, α‐linolenic) on C. growth, morphology, biofilm formation. Each acid was individually introduced to 29544 both sole carbon source an addition complex media. comparison untreated control, bacterial cells treated these showed significant media‐dependent impact growth inhibition. With further characterization, acids, α‐linolenic acid, could be utilized method minimal safety constraints regarding their use food production environment.

Язык: Английский

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