Association between periodontal diseases and cardiovascular diseases, diabetes and respiratory diseases: Consensus report of the Joint Workshop by the European Federation of Periodontology (EFP) and the European arm of the World Organization of Family Doctors (WONCA Europe)

Journal Of Clinical Periodontology, Год журнала: 2023, Номер 50(6), С. 819 - 841

Опубликована: Март 20, 2023

Abstract Aim To explore the implications for dentists and family doctors of association between periodontal systemic diseases role in managing non‐communicable (NCDs) promoting healthy lifestyles. Materials Methods The consensus reports previous Focused Workshops on associations periodontitis diabetes (2017) cardiovascular (2019) formed technical reviews to underpin discussions both topics. For with respiratory diseases, a systematic review was specifically commissioned Workshop discussions. Working groups prepared proposals independently, then were discussed approved at plenary meetings. Results Periodontitis is independently associated diabetes, chronic obstructive pulmonary disease (COPD), sleep apnea COVID‐19 complications. Dentists should collaborate NCDs, implementing strategies early detection primary care centres or dental settings. Family be informed about their consequences, oral health professionals (OHPs) relevance NCDs risk factors. Conclusions Closer collaboration OHPs important management Pathways case medicine practices developed evaluated.

Язык: Английский

---

Periodontal diseases and cardiovascular diseases, diabetes, and respiratory diseases: Summary of the consensus report by the European Federation of Periodontology and WONCA Europe

European Journal of General Practice, Год журнала: 2024, Номер 30(1)

Опубликована: Март 21, 2024

Periodontitis is a chronic inflammatory non-communicable disease (NCD) characterised by the destruction of tooth-supporting apparatus (periodontium), including alveolar bone, presence periodontal pockets, and bleeding on probing.

Язык: Английский

---

Microbes Saving Lives and Reducing Suffering

Microbial Biotechnology, Год журнала: 2025, Номер 18(1)

Опубликована: Янв. 1, 2025

Язык: Английский

---

Air Pollution and Oral Health: An Overall Insight From Genetic Causality

International Dental Journal, Год журнала: 2025, Номер unknown

Опубликована: Фев. 1, 2025

A growing body of epidemiological data consistently links air pollution to various adverse health outcomes. However, the potential connection between and risk oral diseases remains underexplored. This study utilized a two-sample Mendelian randomization approach assess causal relationship diseases. Six categories were considered as exposures: nitrogen oxides (NOx), dioxide (NO2), particulate matter (PM2.5, PM2.5-10, PM10), PM2.5 absorbance. The outcomes included 18 health-related drawn from Finngen R10 dataset, Gene-Lifestyle Interactions in Dental Endpoints consortium, Oncoarray cavity oropharyngeal cancer consortium. Sensitivity analyses performed validate primary inverse-variance weighted estimates using methods such median, mode, MR Egger. analysis demonstrated detrimental effect on multiple conditions, yielding 5 positive associations including with leukoplakia, gingivitis periodontitis; PM2.5-10 pulp periapical diseases, NO2 periodontitis, cavity, salivary glands jaws tests showed no evidence heterogeneity or pleiotropy, affirming robustness findings. highlights impact health, emphasizing need for further research into underlying mechanisms interactions. These findings reinforce importance implementing environmental interventions mitigate associated risks health.

Язык: Английский

---

Periodontal Disease and Alzheimer’s: Insights from a Systematic Literature Network Analysis

The Journal of Prevention of Alzheimer s Disease, Год журнала: 2024, Номер unknown

Опубликована: Янв. 1, 2024

Язык: Английский

---

Periodontitis: An often-neglected complication of diabetes

World Journal of Diabetes, Год журнала: 2024, Номер 15(3), С. 318 - 325

Опубликована: Март 15, 2024

The bidirectional association between type 2 diabetes mellitus (T2DM) and periodontitis is now well established, resulting in periodontal disease being considered as the 6th major complication of (DM) after car-diovascular disease, eye neuropathy, nephropathy, peripheral vascular disease. DM can worsen virulence invasiveness pathogenic oral microbial flora aggravating local inflammation infection those with On other hand, chemical immunological mediators released into circulation part systemic insulin resistance worsening T2DM. Periodontitis if undiagnosed or left untreated also result eventual tooth loss. A study by Xu et al World Journal Diabetes examined predictive factors associated Chinese patients prevalence was found to be 75.7% this study. Based on logistic regression analysis, for higher risk were low brushing frequency [odds ratio (OR) = 4.3], high triglycerides (TG; OR 3.31), total cholesterol (TC; 2.87), glycated hemoglobin (HbA1c; 2.55), age (OR 1.05) while education level protective 0.53). However, most influential variables HbA1c followed age, TC, TG, level, frequency, sex random forest model (this showed sensitivity predicting risk). good understanding predictors T2DM important prevention, early detection susceptible patients, intervention improve health enable long-term glycaemic control observed .

Язык: Английский

---

Associations between different triglyceride glucose index-related obesity indices and periodontitis: results from NHANES 2009–2014

Lipids in Health and Disease, Год журнала: 2024, Номер 23(1)

Опубликована: Июль 5, 2024

Abstract Background This study aimed to explore the associations between triglyceride glucose (TyG) index-related obesity indices and periodontitis within American population. Methods cross-sectional investigation utilized data from National Health Nutrition Examination Survey (NHANES) for 2009–2014. The association TyG–waist-to-height ratio (TyG-WHtR), TyG–weight-adjusted-waist index (TyG-WWI), TyG–waist circumference (TyG-WC), or TyG–body mass (TyG-BMI) was investigated utilizing multivariable logistic regression model, subgroup, dose-response curve analyses. Results enrolled 4,808 adult participants. Except TyG-BMI, which did not exhibit a relationship with periodontitis, TyG-WHtR, [odds (OR) (95% confidence interval (CI))] = 2.83 [1.58–5.10], P 0.002], TyG-WWI [OR CI) 7.50 (3.06–18.34), < 0.001], TyG-WC 2.12 (1.23–3.64), 0.011] were all associated periodontitis. Participants in highest quartile displayed an elevated risk of relative their counterparts lowest quartile, as evidenced 1.72 (1.26–2.33), 0.001] 1.50 (1.13–1.99), 0.009] full adjustment model. Subgroup analyses suggested more pronounced positive these participants who 60 years old, had BMI ≥ 25, have diabetes. indicated linear responses associations. Conclusions identified significant stable TyG-WWI, implies robust correlation high insulin resistance susceptibility

Язык: Английский

---

Sleep and periodontal health

Periodontology 2000, Год журнала: 2024, Номер unknown

Опубликована: Сен. 4, 2024

Abstract Sleep is fundamental for health and well‐being. An adequate amount quality of sleep a cardinal component healthy lifestyle at the basis prevention many non‐communicable chronic diseases. Recent evidence suggests that disorders, particularly obstructive apnea, represent an emerging risk factor periodontal health. This review article provides critical appraisal existing literature concerning association between duration, quality, disorders in general, apnea with diseases, including gingivitis periodontitis. The putative mechanisms underlying these associations are described as well potential clinical implications diagnosis treatment.

Язык: Английский

---

Revolutionizing Oral Care: Reactive Oxygen Species (ROS)-Regulating Biomaterials for Combating Infection and Inflammation

Redox Biology, Год журнала: 2024, Номер 79, С. 103451 - 103451

Опубликована: Ноя. 30, 2024

Язык: Английский

---

Oral and systemic health: is there a “new” link with COVID-19?

Clinical Oral Investigations, Год журнала: 2023, Номер 27(S1), С. 3 - 13

Опубликована: Апрель 20, 2023

Abstract Objectives The objective of the present narrative review was to evaluate evidence a possible association between periodontitis and COVID-19, its biological plausibility, using as models potential associations with cardiovascular diseases, diabetes, some respiratory diseases. Methods A recent systematic used main reference explore different including following two focussed questions: PECOS question, aimed epidemiological evidence, PICOS designed derived from intervention studies. In addition that other relevant scientific documents, consensus papers, were carefully selected appraised. Findings Convincing found support plausibility behind those is based on four factors: (1) bacteraemia oral bacteria periodontal pathogens, (2) increased systemic inflammation, (3) common genetic factors, (4) environmental risk factors. Limited initial available an COVID-19 complications. Among proposed factors explain suggested association, combination previously mentioned plus additional related SARS-CoV-2 characteristics pathogenicity, has been suggested. Conclusions Initial suggests may be associated more severe higher death due COVID-19. Clinical relevance Due severity for efforts should made improve health, promotion healthy habits, such hygiene.

Язык: Английский

---