A bibliometrics study on the status quo and hot topics of pathogenesis of psoriasis based on Web of Science

Skin Research and Technology, Год журнала: 2024, Номер 30(1)

Опубликована: Янв. 1, 2024

Abstract Background Psoriasis is an immune‐mediated chronic inflammatory skin disease. Great progress has been made in the pathogenesis of psoriasis recent years, but there no bibliometric study on psoriasis. The purpose this was to use bibliometrics method analyze research overview and hot spots 10 so as further understand development trend frontier field. Methods core literatures were searched Web Science database, analyzed by VOSviewer, CiteSpace, Bibliometrix terms annual publication volume, country, institution, author, journal, keywords, on. Results A total 3570 included. China United States main countries field, Rockefeller University institution. Krueger JG, had highest number publications greatest influence, Boehncke (2015) most cited local literature. J INVEST DERMATOL takes top spot Dermatol articles citation frequency. hotspots are follows: (1) interaction between innate adaptive immunity related loop dominated Th17 cells IL‐23/IL‐17 axis still key mechanisms psoriasis; (2) molecular genetic studies represented Long Non‐Coding RNA (LncRNA); (3) integrated multi‐omics techniques gut microbiota; (4) Exploring comorbidity mechanism Metabolic Syndrome (MetS). Conclusion This a summary current status psoriasis, which will provide some reference for scholars studying

Язык: Английский

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The causal relationship between serum metabolites and the risk of psoriasis: a Mendelian randomization and meta-analysis study

Frontiers in Immunology, Год журнала: 2024, Номер 15

Опубликована: Март 11, 2024

Objective To explore the influence of serum metabolites on risk psoriasis. Methods In initial stage, we applied Mendelian randomization to evaluate association between 1,400 and Causal effects were primarily assessed through Inverse-Variance Weighted method Wald Ratio’s odds ratios, 95% confidence intervals. False Discovery Rate was used for multiple comparison corrections. Sensitivity analyses conducted using Cochran’s Q Test, MR-PRESSO. MR-Steiger Test employed check reverse causality. validation sought other sources psoriasis GWAS data verify results meta-analysis combine effect sizes obtain robust causal relationships. addition, also metabolic pathway enrichment analysis known that have a relationship with in both stages. Results identified 112 causally associated psoriasis, including 32 metabolite ratios 80 (69 11 unknown). 24 (16 known, 1 unknown, 7 ratios) confirmed onset. Meta-analysis showed overall combined consistent main direction Of 16 metabolites, most attributed lipid metabolism, 5 as factors 8 protective Peptidic Gamma-glutamylvaline levels had negative while exogenous Catechol sulfate amino acid 3-methylglutaconate positive disease The two stages are mainly enriched following pathways: Glutathione Alpha Linolenic Acid Linoleic Metabolism, Biosynthesis unsaturated fatty acids, Arachidonic Glycerophospholipid metabolism. Conclusion Circulating may potential risk, targeting specific benefit diagnosis, assessment, treatment.

Язык: Английский

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A bibliometric analysis of global research on microbial immune microenvironment in melanoma from 2012 to 2022

Skin Research and Technology, Год журнала: 2024, Номер 30(8)

Опубликована: Авг. 1, 2024

Abstract Background Melanoma is an aggressive malignancy primarily impacting the skin, mucous membranes, and pigment epithelium. The tumor microbial microenvironment encompasses both microorganisms inhabiting vicinity environmental factors influencing their interactions. Emerging evidence highlights pivotal role of immune in melanoma. Methods We conducted extensive review scholarly works published from 2012 to 2022, utilizing Web Science Core Collection. Subsequently, we employed analytical tools such as VOSviewer, CiteSpace, R programming language scrutinize prevailing research patterns within this domain. Results A sum 513 articles were pinpointed, with notable input coming United States China. Harvard University stood out top‐contributing institution, while journal received most citations. Current sphere chiefly focuses on two principal domains: gut microbiota PD‐L1 pathway concerning melanoma treatment. Conclusion study offers analysis overview worldwide landscape a focus microbes It underscores promising prospects for harnessing microenvironment's potential These findings furnish valuable insights guidance advancing scientific inquiry refining clinical approaches dynamic field.

Язык: Английский

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Advances in stem cells treatment of diabetic wounds: A bibliometric analysis via CiteSpace

Skin Research and Technology, Год журнала: 2024, Номер 30(4)

Опубликована: Апрель 1, 2024

Abstract Diabetes is a chronic medical condition that may induce complications such as poor wound healing. Stem cell therapies have shown promise in treating diabetic wounds with pre‐clinical and clinical studies. However, little bibliometric analysis has been carried out on stem cells the treatment of wounds. In this study, we retrieved relevant papers published from January 1, 2003, to December 31, 2023, Chinese English databases. CiteSpace software was used analyze authors, institutions, keywords by standard indicators. Our findings indicated publications kept increasing. The most prolific author Qian Cai ( n = 7) Mohammad Bayat 16) databases, respectively. Institutions distribution showed institutions conducted publications, institution People's Liberation Army General Hospital 9) Shahid Beheshti University Medical Sciences 17) highest centrality keyword databases “wound healing” (0.54) “in vitro” (0.13), There were 8 11 efficient convincing clusters produced log‐likelihood ratio strongest burst “exosome” (strength 3.57) “endothelial progenitor cells” 7.87) These direction for future research

Язык: Английский

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A bibliometric analysis and visualization of acupuncture and moxibustion therapy for herpes zoster and postherpetic neuralgia

Skin Research and Technology, Год журнала: 2024, Номер 30(6)

Опубликована: Июнь 1, 2024

Abstract Objective To identify major contributors, current research status, and to forecast trends future development prospects on acupuncture moxibustion therapy for herpes zoster (HZ) postherpetic neuralgia (PHN). Methods A systematic search was conducted the China National Knowledge Infrastructure (CNKI), Weipu, WanFang databases, Web of Science Core Collection (WoSCC), PubMed, Scopus databases. The strategy included relevant terms HZ, PHN, acupuncture, moxibustion. reference type limited articles or reviews, with a publication date from January 1, 2014 December 31, 2023. Data analysis performed using CiteSpace software, focusing author, institution, source, keyword distributions, temporal trends. Results total 1612 publications were identified both Chinese English revealed rising trend in numbers database, significant increase observed 2020. In activity exhibited two peaks 2019 Guohua Lin Jingchun Zeng most prolific authors respectively. Chengdu University TCM Zhejiang Medicine active institutions. “herpes zoster” as frequent while “postherpetic neuralgia,” “acupuncture,” “management” prominent database. study also several therapeutic approaches, including fire needle electroacupuncture, which have shown efficacy treating HZ PHN. Animal studies provided insights into mechanisms these therapies, suggesting potential modulation neuroinflammatory markers intracellular signaling pathways. Conclusion bibliometric underscores growing interest It highlights contributions key institutions pinpointing areas research. advocates necessity large‐scale, multi‐center clinical trials further basic mechanical optimize therapies. Moreover, it emphasizes importance international collaboration strengthen evidence base expand global impact this traditional treatment modality.

Язык: Английский

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Global research trends in cutaneous neurofibromas: A bibliometric analysis from 2003 to 2022

Skin Research and Technology, Год журнала: 2024, Номер 30(2)

Опубликована: Янв. 26, 2024

Neurofibromatosis type 1 (NF1) is a common inherited disorder characterized by cutaneous neurofibromas and other features. It still challenge in managing inoperable patients the complex nature of disease. Bibliometric analyses for (cNF) could offer insights into impactful research collaborations, guiding future efforts to improve patient care outcomes.

Язык: Английский

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Identification of novel disulfidptosis‐related lncRNA signatures to predict the prognosis and immune microenvironment of skin cutaneous melanoma patients

Skin Research and Technology, Год журнала: 2024, Номер 30(7)

Опубликована: Июнь 25, 2024

Abstract Background Skin cutaneous melanoma (SKCM) is an aggressive form of malignant with poor prognosis and high mortality rates. Disulfidptosis a newly discovered cell death regulatory mechanism caused by the abnormal accumulation disulfides. This unique pathway guiding significant new research to understand cancer progression for targeted treatment. However, correlation between disulfidptosis long non‐coding RNAs (lncRNAs) in SKCM remains unknown at present. Methods The Cancer Genome Atlas database furnished lncRNA expression data clinical information patients. Pearson Cox regression analyses identified disulfidptosis‐related lncRNAs associated prognosis. ROC curves nomogram validated model. TME, immune infiltration, GSEA analysis, checkpoint gene profiling, drug sensitivity were assessed low‐risk groups. Consistent clustering categorized patients personalized treatment guidance. Results A total twelve development prediction models. area under curve (AUC) values provided reliable discrimination evaluate prognostic potential TME played crucial role tumorigenesis, prognosis, risk scores closely related infiltration. Meanwhile, combination chemotherapy, therapy, immunotherapy was recommended based on efficacy analyses. Conclusion We model that could be used predict help guide chemotherapy plans.

Язык: Английский

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m6A‐ and m5C‐ modified lncRNAs orchestrate the prognosis in cutaneous melanoma and m6A‐ modified LINC00893 regulates cutaneous melanoma cell metastasis

Skin Research and Technology, Год журнала: 2024, Номер 30(7)

Опубликована: Июль 1, 2024

Abstract Background As the most important modifications on RNA level, N6‐methyladenosine (m6A‐) and 5‐methylcytosine (m5C‐) modification could have a direct influence RNAs. Long non‐coding RNAs (lncRNAs) also be modified by methylcytosine modification. Compared with mRNAs, function of lncRNAs more potent to some extent in biological processes like tumorigenesis. Until now, rare reports been done associated cutaneous melanoma. Herein, we wonder if m6A‐ m5C‐ immune landscape prognosis melanoma, want find which directly affect malignant behaviors Methods Systematically, explored expression pattern melanoma from datasets including UCSC Xena NCBI GEO, prognostic were selected. Then, according lncRNAs, samples these divided into several subtypes. Prognostic model, nomogram survival drug sensitivity, GO, KEGG pathway analysis performed. Furthermore, among selected identified one lncRNA named LINC00893 investigated its cell lines. Results We 27 related significantly survival, made subtype based lncRNAs. Among two subtypes, found differences cells infiltration between LASSO algorithm was used screen optimized combination ZNF252P‐AS1, MIAT, FAM13A‐AS1, LINC‐PINT, LINC00893, AGAP2‐AS1, OIP5‐AS1, SEMA6A‐AS1. that there significant correlation different risk groups predicted RS model actual prognosis. The independent factors constructed. Besides, sensitivity chemotherapeutic agents, GO In groups, total 14 molecules distributions obtained, included AZD6482, AZD7762, AZD8055, camptothecin, dasatinib, erlotinib, gefitinib, gemcitabine, GSK269962A, nilotinib, rapamycin, sorafenib. A 55 17 signaling pathways screened. At last, noticed had relatively lower tissue lines compared adjacent tissues epidermal melanocyte, down‐regulation promote behavior A875 MV3. lines, m6A‐related YTHDF3 METTL3 LINC00893. Conclusion an prediction lncRNAs’ role prognosis, tumor microenvironment, infiltration, clinicopathological features. is potentially regulated m6A modification, serve as tumor‐suppressor play inhibitory metastasis.

Язык: Английский

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Exploring the landscape of extracellular vesicle application for skin and plastic surgery: A bibliometric analysis from 2003 to 2023

Skin Research and Technology, Год журнала: 2024, Номер 30(8)

Опубликована: Июль 31, 2024

Abstract Background Exosomes and other secretory membrane vesicles, collectively referred to as extracellular vesicles (EVs), have garnered increasing attention in research due their biological characteristics. Notably, studies shown promising results regarding the role of stem cell‐derived (SC‐EVs) skin plastic surgery applications. This study aims elucidate current trends SC‐EVs within context offer insights for future directions advancing this critical field. Methods A comprehensive search was conducted relevant on spanning from 2003 2023, utilizing Web Science database. Subsequently, data analysis performed using VOSviewer CiteSpace. Results total 1089 were identified, with a noticeable annual increase publications SC‐EVs' application surgery. China emerged leading contributor field, Shanghai Jiao Tong University being notable institution. Stem Cell Research & Therapy International Journal Molecular Sciences top journals publishing articles. Author Fu Xiaobing Chinese People's Liberation Army General Hospital had highest publication count area. Keyword co‐occurrence revealed six distinct clusters, “exosomes” most prevalent keyword recent years. Wound healing rejuvenation primary focuses hotspots Conclusion review offers into global surrounding Analysis journals, institutions, references, keywords provides valuable guidance researchers determining directions.

Язык: Английский

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A bibliometric and visual analysis of the research status and hotspots of seborrheic dermatitis based on web of science

Skin Research and Technology, Год журнала: 2024, Номер 30(9)

Опубликована: Сен. 1, 2024

Abstract Background Seborrheic dermatitis (SD) is a common chronic inflammatory skin disease. In recent years, significant progress has been made in the field of SD, but there no bibliometric research yet. This study aims to use methods analyze current status and hot topics understand further trends future development prospects this field. Methods Retrieve core literature on SD from Web Science database conduct detailed analysis using CiteSpace VOSviewer software based factors such as publication volume, countries (regions), institutions, journals, authors, highly‐cited papers, keywords. Results From 1996 2024, total 1436 publications were included analysis. The number shown an increasing trend year by year. USA leading country research. University California System primary institution. International Journal Dermatology journal with highest publications. author Yang Won Lee publications, while article “Seborrheic Dermatitis” (2004) Gupta, A.K. cited most. dermatitis” most frequently occurring keyword. main hotspots frontiers are follows: (1) relationship between other diseases popular topic; (2) Malassezia inflammation SD; (3) Focusing antifungal anti‐inflammatory treatments for frontier direction Conclusion summary research, which helps clinical doctors researchers quickly insights valuable information provides reference decision‐making finding directions.

Язык: Английский

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