Environmental Research, Год журнала: 2023, Номер 233, С. 116506 - 116506
Опубликована: Июнь 25, 2023
Язык: Английский
Molecular Cancer, Год журнала: 2023, Номер 22(1)
Опубликована: Июнь 21, 2023
Abstract Cancer is a grievous disease whose treatment requires more efficient, non-invasive therapy, associated with minimal side effects. Gold nanoparticles possessing greatly impressive optical properties have been forerunner in bioengineered cancer therapy. This theranostic system has gained immense popularity and finds its application the field of molecular detection, biological imaging, cell targeting, etc. The photothermal property nanoparticles, especially gold nanorods, causes absorption light incident by source, transforms it into heat, resulting tumor destruction. review describes different features summarizes advance research done for precisely nanorods combating various cancers including breast, lung, colon, oral, prostate, pancreatic cancer.
Язык: Английский
Процитировано
160
Molecular Cancer, Год журнала: 2023, Номер 22(1)
Опубликована: Окт. 6, 2023
Abstract Skin cancer is a global threat to the healthcare system and estimated incline tremendously in next 20 years, if not diagnosed at an early stage. Even though it curable stage, novel drug identification, clinical success, resistance another major challenge. To bridge gap bring effective treatment, important understand etiology of skin carcinoma, mechanism cell proliferation, factors affecting growth, resistance. The current article focusses on understanding structural diversity cancers, treatments available till date including phytocompounds, chemotherapy, radiotherapy, photothermal therapy, surgery, combination molecular targets associated with growth metastasis, special emphasis nanotechnology-based approaches for downregulating deleterious disease. A detailed analysis respect types nanoparticles their scope overcoming multidrug as well trials has been discussed. Graphical
Язык: Английский
Процитировано
105
International Journal of Biological Macromolecules, Год журнала: 2023, Номер 253, С. 127143 - 127143
Опубликована: Окт. 2, 2023
Язык: Английский
Процитировано
98
Signal Transduction and Targeted Therapy, Год журнала: 2024, Номер 9(1)
Опубликована: Авг. 12, 2024
Cancer remains a significant risk to human health. Nanomedicine is new multidisciplinary field that garnering lot of interest and investigation. shows great potential for cancer diagnosis treatment. Specifically engineered nanoparticles can be employed as contrast agents in diagnostics enable high sensitivity high-resolution tumor detection by imaging examinations. Novel approaches labeling are also made possible the use nanoprobes nanobiosensors. The achievement targeted medication delivery therapy accomplished through rational design manufacture nanodrug carriers. Nanoparticles have capability effectively transport medications or gene fragments tissues via passive active targeting processes, thus enhancing treatment outcomes while minimizing harm healthy tissues. Simultaneously, context radiation sensitization photothermal enhance therapeutic efficacy malignant tumors. This review presents literature overview summary how nanotechnology used According oncological diseases originating from different systems body combining pathophysiological features cancers at sites, we most recent developments applications. Finally, briefly discuss prospects challenges cancer.
Язык: Английский
Процитировано
81
European Polymer Journal, Год журнала: 2023, Номер 187, С. 111898 - 111898
Опубликована: Фев. 13, 2023
Язык: Английский
Процитировано
63
Photodiagnosis and Photodynamic Therapy, Год журнала: 2024, Номер 45, С. 103959 - 103959
Опубликована: Янв. 21, 2024
Breast cancer (BC) remains an enigmatic fatal modality ubiquitously prevalent in different parts of the world. Contemporary medicines face severe challenges remediating and healing breast cancer. Due to its spatial specificity nominal invasive therapeutic regime, photothermal therapy (PTT) has attracted much scientific attention down lane. PTT utilizes a near-infrared (NIR) light source irradiate tumor target intravenously or non-invasively, which is converted into heat energy over optical fibre. Dynamic progress nanomaterial synthesis was achieved with specialized visual, physicochemical, biological, pharmacological features make up for inadequacies expand horizon PTT. Numerous nanomaterials have substantial NIR absorption can function as efficient transducers. It achievable limit wavelength range absorbance peak specific by manipulating their synthesis, enhancing precision quality Along same lines, various are conjugated wide surface-modifying chemicals, including polymers antibodies, may modify persistence diminish toxicity concerns. In this article, we tend put forth insights fundamental conceptualizations on pre-existing advances upon conjugation biocompatible working synergy combat cancer, encompassing several strategies like immunotherapy, chemotherapy, photodynamic therapy, radiotherapy coupled Additionally, role mechanisms nanoparticles, well possible alternatives PTT, summarized distinctive integral aspect article.
Язык: Английский
Процитировано
55
International Journal of Pharmaceutics, Год журнала: 2023, Номер 643, С. 123276 - 123276
Опубликована: Июль 27, 2023
Язык: Английский
Процитировано
50
European Polymer Journal, Год журнала: 2023, Номер 193, С. 112111 - 112111
Опубликована: Май 5, 2023
Язык: Английский
Процитировано
43
Molecular Cancer, Год журнала: 2023, Номер 22(1)
Опубликована: Май 25, 2023
The advent of nanotechnology has opened new possibilities for bioimaging. Metal nanoparticles (such as gold, silver, iron, copper, etc.) hold tremendous potential and offer enormous opportunities imaging diagnostics due to their broad optical characteristics, ease manufacturing technique, simple surface modification. arginine-glycine-aspartate (RGD) peptide is a three-amino acid sequence that seems have considerably greater ability adhere integrin adhesion molecules exclusively express on tumour cells. RGD peptides act the efficient tailoring ligand with variety benefits including non-toxicity, precision, rapid clearance, etc. This review focuses possibility non-invasive cancer using metal assistance.
Язык: Английский
Процитировано
42
Materials Today Chemistry, Год журнала: 2024, Номер 35, С. 101894 - 101894
Опубликована: Янв. 1, 2024
Язык: Английский
Процитировано
34