BMJ Quality & Safety,
Год журнала:
2024,
Номер
33(7), С. 470 - 478
Опубликована: Апрель 4, 2024
Mixed
methods
research
is
a
popular
approach
used
to
understand
persistent
and
complex
problems
related
quality
safety,
such
as
reasons
why
interventions
are
not
implemented
intended
or
explaining
differential
outcomes.
However,
the
rigour
of
mixed
proposals
publications
often
miss
opportunities
for
integration,
which
core
methods.
Achieving
integration
remains
challenging,
failing
integrate
reduces
benefits
approach.
Therefore,
purpose
this
article
guide
safety
researchers
in
planning
designing
study
that
facilitates
integration.
We
highlight
how
meaningful
can
be
achieved
by
centring
at
following
levels:
question,
design,
methods,
results
reporting
interpretation
levels.
A
holistic
view
through
all
these
levels
will
enable
provide
better
answers
thereby
contribute
improvement
care.
Journal of Clinical Oncology,
Год журнала:
2023,
Номер
41(28), С. 4562 - 4591
Опубликована: Авг. 15, 2023
To
provide
evidence-based
recommendations
to
health
care
providers
on
integrative
approaches
managing
anxiety
and
depression
symptoms
in
adults
living
with
cancer.The
Society
for
Integrative
Oncology
ASCO
convened
an
expert
panel
of
oncology,
medical
radiation
surgical
palliative
social
sciences,
mind-body
medicine,
nursing,
methodology,
patient
advocacy
representatives.
The
literature
search
included
systematic
reviews,
meta-analyses,
randomized
controlled
trials
published
from
1990
through
2023.
Outcomes
interest
or
as
measured
by
validated
psychometric
tools,
adverse
events.
Expert
members
used
this
evidence
informal
consensus
the
Guidelines
into
Decision
Support
methodology
develop
guideline
recommendations.The
identified
110
relevant
studies
(30
reviews
80
trials)
inform
base
guideline.Recommendations
were
made
mindfulness-based
interventions
(MBIs),
yoga,
relaxation,
music
therapy,
reflexology,
aromatherapy
(using
inhalation)
treating
during
active
treatment;
MBIs,
acupuncture,
tai
chi
and/or
qigong,
reflexology
after
cancer
treatment.
For
symptoms,
recommended
treatment,
qigong
post-treatment.Issues
patient-health
provider
communication,
disparities,
comorbid
conditions,
cost
implications,
implementation,
training
credentialing,
quality
assurance
natural
products
are
discussed.
While
several
such
MBIs
yoga
appear
effective,
limitations
including
assessment
risk
bias,
nonstandardization
therapies,
lack
diversity
study
samples,
control
conditions
well
future
research
directions
discussed.Additional
information
is
available
at
www.asco.org/survivorship-guidelines.
Journal of the American Geriatrics Society,
Год журнала:
2023,
Номер
71(7), С. 2350 - 2356
Опубликована: Фев. 25, 2023
Advance
care
planning
(ACP)
was
initially
narrowly
defined
as
documentation
of
life-sustaining
treatment
(LST).
One
initial
goal
to
curb
unwanted
LSTs
and
costs.1
Yet,
a
focus
solely
on
legal
LST
preferences
has
resulted
in
mixed
data
goal-concordant
healthcare
utilization.2-4
Fortunately,
the
conceptualization
ACP
continues
evolve,
is
now
widely
recognized
process
preparing
patients
(people)
surrogate
decision-makers
for
communication
medical
decision-making.5,
6
This
involves
complex
array
patient,
surrogate,
clinician
behaviors,
health
systems
workflows,
interventions,
communities,
policy.
rooted
what
quality
life
means
people.4,
5,
7
However,
antiquated
narrow
definitions
one-time
checkbox
or
code
status
persist,
resulting
heterogeneous
research,
clinical,
policy
initiatives.2,
4
To
address
this
heterogeneity,
modified
Delphi
panel
2017
"a
that
supports
adults
at
any
age
stage
understanding
sharing
their
personal
values,
goals,
regarding
future
care."7
As
field
evolved,
definition
focused
"future
decisions"
proven
be
too
it
does
not
include
preparation
surrogates
decision-making
over
course
public
perceptions
ACP.8-10
The
use
non-standardized
potentially
inappropriate
outcomes
research
also
makes
difficult
evaluate
ACP's
effectiveness.4,
11
Goal-concordant
been
considered
"gold
standard,"
but
there
lack
validated
standardized
measures.12-15
Because
patient
may
change,
reliance
retrospective
chart
review
assess
concordance
inaccurate,13,
14
growing
consensus
should
one
key
research.6
Additionally,
unlikely
affect
some
such
life,
which
impacted
by
other
factors
symptom
burden,
available
support,
so
forth,
utilization,
patient-centered
affected
access,
systemic
injustice,
issues.12,
16
Furthermore,
unique
needs
historically
marginalized
populations
are
well
represented
prior
identification.
Rates
much
lower
(<20%)
among
racially
ethnically
minoritized
those
with
limited
literacy.17-19
Disparities
persist
lesbian,
gay,
bisexual,
transgender,
queer,
intersexual,
asexual,
homeless,
incarcerated
populations.20,
21
Reasons
access
healthcare,
experiential
discrimination,
well-founded
mistrust,22,
23
culturally
diverse
views
autonomy
decision-making,24,
25
making
preferable
many
begin
discussions
communities.
Diverse
interdisciplinary
clinicians
community-based
experts,
have
included
efforts
define
outcomes.
We
propose
new
framework
reflects
updated
conceptualizes
part
continuum
planning.
overarching
construct
under
"Care
Planning
Umbrella"
focuses
decision-making,5
brings
meaning
purpose
fundamental
cornerstone.
Underneath
broader
umbrella
multiple
steps,
people,
clinical
community
decisions—some
in-the-moment
advance.
Care
shaped
person's
(or
surrogate's)
life;
these
constructs
dynamic
evolve
time.28
It
an
individual's
readiness,
control
decision-making,
illness
understanding,
prognostic
awareness,
acceptable/unacceptable
tradeoffs.5
All
influenced
family
caregiver
social
norms,
accessible
resources,
current
Umbrella
spans
people
move
between
healthy/chronic
illness,
serious
end
life.
They
face
different
types
decisions
(e.g.,
diabetes
medication
regimen
chronically
ill,
chemotherapy
seriously
hospice
life),
receive
settings
community,
outpatient,
acute
care,
long-term
hospice).5,
29
must
tailored
course,
they
facing,
based
person
time.
For
example,
although
designation
integration
into
appropriate
every
stage,
appropriateness
integrating
awareness
tradeoffs
will
vary
(Figure
1).30,
31
At
all
stages,
treatment,
chemotherapy,
end-of-life
procedures)
advance
setting
preferences).
Over
lines
advanced
fluid.3,
30,
even
early
strong
enduring
about
experiences
beliefs.
Those
individuals
given
opportunity
discuss
document
while
educating
them
change
time
revisited.
onus
our
disentangle
complexity
(i.e.,
planning)
caregivers
desire
studies
show
decreases
distress.4
Based
recent
consensus,
more
clinically
meaningful
from
perspective
burden
distress;
feeling
heard
understood;
satisfaction
communication,
decision-making.4,
In
addition,
implementation
science
human
engineering
can
used
help
achieve
its
next
step
evolutionary
process.
Implementation
offers
tools
understand
processes,
including
determining
strategies
meet
families.32
System-level
strategic
approaches
consider
organizational
preferred
examination
individual
components
interventions
clinicians).2,
4,
33-35
recently
Consolidated
Framework
Research
(CFIR)
well-established
implementing
evidence-based
real-world
settings.36,
37
CFIR
provides
guide
systematically
identifying
determine
whether
programs
succeed
fail.
recognizes
barriers
arise
level
identify
overcome
barriers.
consists
five,
interrelated
domains
(see
Table
1
Supplemental
figure
[Appendix
S1]):
Outer
Setting
cultural/social
racism,
policies
laws,
information
exchanges,
metrics,
reimbursement,
etc.);
Inner
system
readiness
policies,
incentives,
EMR
infrastructure);
Individuals
disease
trajectory;
cultural
backgrounds;
racism
mistrust
Capacity,
Opportunity,
Motivation
(COM-B)38);
Innovation
design
caregivers:
educational
modalities;
documentation;
navigators;
events,
medical-legal
partnerships,
etc.
staff:
training
protocols;
conversation
guides;
electronic
record
(EMR)
templates,
Process39,
40
degree
collaboration
across
leadership,
multidisciplinary
teams,
settings;
champions;
buy-in;
populations;
messaging
marketing,
improvement,
etc.).
design:
How
assembled
presented
Structural
characteristics
Relational
Connections/Communication
Culture
recipient
patients,
caregivers,
clinicians):
Capability,
(COM-B)
Model
Behavior
Change
Human
methods
applied
how
engage
processes
improve
play
role
improving
planning.41
Process
mapping
visualize
relevant
workflows
tasks
parties
clinicians,
surrogates,
members,
faith
leaders,
attorneys,
etc.)
using
multiple,
iterative
steps.
Integrating
model
ensure
complete
involved.
likely
require
maps
fully
reflect
parties,
settings,
patients'
necessary
care.
requires
broad
range
partners
extends
beyond
where
live
others
shown,
outreach
patient-or
community-facing
needed,
addition
goals
conversations.42
Future
need
representatives
nurses,
workers,
chaplains,
navigators)
experts
faith-based
attorneys).
evolved
past
several
decades
still
evolving.
get
we
reconceptualize
holistic,
ongoing
includes
both
stage.
suggest
systems-level
approach
evidenced-based
inclusion
communities
develop
support
settings.
Concept
figures:
Susan
E.
Hickman,
Rebecca
L.
Sudore;
Preparation
manuscript:
Hillary
D.
Lum,
Anne
M
Walling,
April
Savoy,
Sudore.
Thank
you
graphic
artist
Kaylee
Stewart
helping
us
communicate
ideas
visually.
work
unfunded.
Dr.
Sudore
funded
National
Institute
Aging,
Institutes
Health
(K24AG054415).
Savoy
supported
Career
Development
Award
(K01AG076971).
authors
declare
no
conflict
interest.
unfunded
content
responsibility
authors.
Appendix
S1.
Application
consolidated
Please
note:
publisher
responsible
functionality
supporting
supplied
Any
queries
(other
than
missing
content)
directed
corresponding
author
article.
Journal of Medical Internet Research,
Год журнала:
2023,
Номер
25, С. e48000 - e48000
Опубликована: Июль 25, 2023
Background
Digital
therapeutics
are
patient-facing
digital
health
interventions
that
can
significantly
alter
the
care
landscape.
Despite
being
used
to
successfully
treat
a
range
of
conditions,
their
uptake
in
systems
remains
limited.
Understanding
full
spectrum
factors
is
essential
identify
ways
which
policy
makers
and
providers
facilitate
adoption
effective
within
system,
as
well
steps
developers
take
assist
deployment
products.
Objective
In
this
review,
we
aimed
map
most
frequently
discussed
determine
integration
into
practical
use
by
patients
professionals.
Methods
A
scoping
review
was
conducted
MEDLINE,
Web
Science,
Cochrane
Database
Systematic
Reviews,
Google
Scholar.
Relevant
data
were
extracted
synthesized
using
thematic
analysis.
Results
We
identified
35,541
academic
221
gray
literature
reports,
with
244
(0.69%)
included
covering
35
countries.
Overall,
85
impact
pooled
5
categories:
patient
characteristics,
properties
therapeutics,
characteristics
professionals,
outcomes.
The
need
for
regulatory
framework
stated
factor
at
level.
Demographic
formed
iterated
patient-related
factor,
whereas
literacy
considered
important
Among
interoperability
across
broader
system
emphasized.
Finally,
ability
expand
access
outcome
measure.
Conclusions
developed
offers
multistakeholder
approach
recognizing
pathway
provides
an
analytical
tool
assess
system’s
readiness
therapeutics.
Implementation Science Communications,
Год журнала:
2023,
Номер
4(1)
Опубликована: Май 5, 2023
Healthcare
services
can
be
re-traumatising
for
trauma
survivors
where
they
trigger
memories
of
past
distressing
events
and
exert
limits
to
a
survivor's
sense
autonomy,
choice,
control.
The
benefits
receiving
trauma-informed
healthcare
are
well
established;
however,
factors
that
promote
or
impede
the
implementation
care
not
yet
characterised
understood.
aim
this
review
was
systematically
identify
synthesise
evidence
regarding
reduce
TIC
in
settings.This
systematic
followed
Preferred
Reporting
Items
Systematic
Reviews
Meta-analyses
(PRISMA)
2.0
guidelines.
Scopus,
MEDLINE,
Proquest,
PsycINFO
grey
literature
were
searched
original
research
evaluations
published
between
January
2000
April
2021
reporting
barriers
and/or
facilitating
setting.
Two
reviewers
independently
assessed
quality
each
included
study
using
Mixed
Methods
Appraisal
Tool
(MMAT)
Checklist.Twenty-seven
studies
included,
22
which
USA.
Implementation
occurred
range
health
settings,
predominantly
mental
services.
facilitators
implementing
categorised
as
follows:
intervention
characteristics
(perceived
relevance
setting
target
population),
influences
external
organisation
(e.g.
interagency
collaboration
actions
other
agencies)
within
leadership
engagement,
financial
staffing
resources
policy
procedure
changes
flexibility
protocols).
Other
related
processes
flexible
accessible
training,
service
user
feedback
collection
initiative
outcomes)
finally
individuals
system
such
resistance
change.This
identifies
key
should
targeted
implementation.
Continued
will
helpful
characterising
what
looks
like
when
it
is
delivered
well,
providing
validated
frameworks
organisational
uptake
benefit
survivors.The
protocol
registered
on
PROSPERO
database
(CRD42021242891).
Frontiers in Public Health,
Год журнала:
2023,
Номер
11
Опубликована: Апрель 13, 2023
Physical
activity
is
important
for
children’s
health.
However,
evidence
suggests
that
many
children
and
adults
do
not
meet
international
physical
recommendations.
Current
school-based
interventions
have
had
limited
effect
on
alternative
approaches
are
needed.
Context,
which
includes
school
setting,
ethos,
staff,
sociodemographic
factors,
a
key
largely
ignored
contributing
factor
to
intervention
effectiveness,
impacting
in
several
interacting
ways.
Conceptualization
programs
focus
tightly-constructed
content
ignores
the
context
program
will
be
delivered,
thereby
limiting
effectiveness.
We
propose
move
away
from
uniform
maximize
internal
validity
toward
flexible
approach
enables
schools
tailor
their
specific
context.
Evaluation
designs
of
context-specific
should
explicitly
consider
This
challenging
cluster
randomized
controlled
trial
designs.
Thus,
such
as
natural
experiment
stepped-wedge
warrant
further
consideration.
Primary
outcome
A
collective
average
minutes
moderate-to-vigorous
intensity
may
always
most
appropriate
choice.
wider
range
outcomes
improve
health
long-term.
In
this
paper,
we
argue
greater
consideration
design
analysis
help
overcome
existing
limitations
effective
thus
progress
field.
While
evaluation
untested,
hope
stimulate
debate
issues
future
development
implementation.
SSM - Health Systems,
Год журнала:
2024,
Номер
2, С. 100010 - 100010
Опубликована: Март 24, 2024
Health
systems
across
the
world
experience
pervasive
gaps
in
speed
with
which
high
quality
evidence
is
generated,
implemented
and
refined.
A
Learning
System
(LHS)
approach
that
blends
research
health
care
operations
to
eliminate
or
reduce
delays.
This
paper
builds
on
existing
LHS
frameworks
deepen
our
practical
understanding
of
research-health
interface
provide
actionable
insights
how
realize
a
practice.
We
present
an
action
framework
describes
are
linked
enacted
comprehensive
advance
population
equity.
seeking
implement
can
use
this
identify
capabilities
necessary
enact
learning
elements,
including
key
questions
methods,
ensure
systematic
achieving
equity-centered
quadruple
aim
metrics.
Deleted Journal,
Год журнала:
2024,
Номер
1(1), С. 41 - 46
Опубликована: Янв. 1, 2024
Abstract
Objective:
To
study
implementation
of
mental
health
services
delivery
with
depression
as
tracer
condition
through
Health
and
Wellness
Centres
(HWCs)
under
Ayushman
Bharat
programme
in
India.
Materials
Methods:
Mixed
methods
approach.
The
outcomes
acceptability,
appropriateness
feasibility
were
measured
analysed.
Results:
found
a
low
level
medium
acceptability
for
using
HWCs
platform
the
management
patients
depression.
Increased
availability
trained
human
resources,
improved
infrastructure
drug
availability,
integration
other
programmes
coordination
higher
centres
referral
follow-up
are
suggested
key
interventions
to
enhance
care.
Conclusion:
There
is
need
innovative
model
care
that
places
an
emphasis
on
implement
strategies
maximise
HWCs.
Annual Review of Clinical Psychology,
Год журнала:
2024,
Номер
20(1), С. 21 - 47
Опубликована: Фев. 5, 2024
To
build
a
coherent
knowledge
base
about
what
psychological
intervention
strategies
work,
develop
interventions
that
have
positive
societal
impact,
and
maintain
increase
this
impact
over
time,
it
is
necessary
to
replace
the
classical
treatment
package
research
paradigm.
The
multiphase
optimization
strategy
(MOST)
an
alternative
paradigm
integrates
ideas
from
behavioral
science,
engineering,
implementation
economics,
decision
science.
MOST
enables
of
strategically
balance
effectiveness,
affordability,
scalability,
efficiency.
In
review
we
provide
overview
MOST,
discuss
several
experimental
designs
can
be
used
in
optimization,
consider
how
investigator
use
results
select
components
for
inclusion
optimized
intervention,
application
list
future
issues
rapidly
evolving
field.
We
highlight
feasibility
adopting
new
as
well
its
potential
hasten
progress
JMIR Mental Health,
Год журнала:
2025,
Номер
12, С. e65246 - e65246
Опубликована: Янв. 20, 2025
Background
Digital
mental
health
interventions
(DMHIs)
to
monitor
and
improve
the
of
people
with
psychosis
or
bipolar
disorder
show
promise;
however,
user
engagement
is
variable,
integrated
clinical
use
low.
Objective
This
prospectively
registered
systematic
review
examined
barriers
facilitators
clinician
patient
DMHIs,
inform
implementation
within
real-world
settings.
Methods
A
search
7
databases
identified
empirical
studies
reporting
qualitative
quantitative
data
about
factors
affecting
staff
DMHIs
aiming
physical
disorder.
The
Consolidated
Framework
for
Implementation
Research
was
used
synthesize
on
facilitators,
following
a
best-fit
framework
synthesis
approach.
Results
included
175
papers
(150
studies;
11,446
participants)
describing
randomized
controlled
trials;
surveys;
interviews;
usability,
cohort,
case
studies.
Samples
schizophrenia
spectrum
(98/150,
65.3%
studies),
(62/150,
41.3%
clinicians
(26/150,
17.3%
studies).
Key
were
strong
recognition
DMHIs’
relative
advantages,
clear
link
between
intervention
focus
specific
needs,
simple,
low-effort
digital
interface,
human-supported
delivery,
device
provision
where
needed.
Although
thought
patients
would
lose,
damage,
sell
devices,
reviewed
found
only
11%
loss.
Barriers
complexity,
perceived
risks,
motivation,
discomfort
self-reflection,
poverty,
symptoms
psychosis,
poor
compatibility
existing
workflows,
fears
that
replace
traditional
face-to-face
care,
infrastructure
limitations,
limited
financial
support
delivery.
Conclusions
Identified
highlight
key
considerations
DMHI
development
implementation.
As
broader
implications,
sustainable
business
models
are
needed
ensure
evidence-based
maintained
deployed.
Trial
Registration
PROSPERO
CRD42021282871;
https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=282871