Frontiers in Bioengineering and Biotechnology, Год журнала: 2023, Номер 11
Опубликована: Апрель 6, 2023
As an interdisciplinary field, drug delivery relies on the developments of modern science and technology. Correspondingly, how to upgrade traditional dosage forms for a more efficacious, safer, convenient poses continuous challenge researchers.
Язык: Английский
Journal of Functional Biomaterials, Год журнала: 2022, Номер 13(4), С. 289 - 289
Опубликована: Дек. 9, 2022
Electrospinning is an advanced technology for the preparation of drug-carrying nanofibers that has demonstrated great advantages in biomedical field. Electrospun nanofiber membranes are widely used field drug administration due to their such as large specific surface area and similarity extracellular matrix. Different electrospinning technologies can be prepare different structures, those with a monolithic structure, core–shell Janus or porous structure. It also possible controlled-release functions, sustained release, delayed biphasic targeted release. This paper elaborates on drug-loaded using various concludes mechanisms behind controlled release drugs.
Язык: Английский
Процитировано
104
Polymers, Год журнала: 2022, Номер 14(22), С. 4947 - 4947
Опубликована: Ноя. 16, 2022
The aim of this study was to develop a novel ultrathin fibrous membrane with core-sheath structure as an antioxidant food packaging membrane. prepared by coaxial electrospinning, and the release active substances regulated its special structure. Ferulic acid (FA) incorporated into electrospun zein/polyethylene oxide fibers ensure their synergistic properties. We found that had good morphology smooth surface. internal stable, three materials we used were compatible. For different loading positions, it observed core layer ferulic-acid-loaded sustained action, while sheath pre-burst action. Finally, apples selected for using membranes simulate practical applications. effective in reducing water loss apple quality loss, well extending shelf life. According these experiments, FA-loaded zein/PEO electrospinning fiber can be will also undergo more improvements future.
Язык: Английский
Процитировано
100
Polymers, Год журнала: 2022, Номер 14(20), С. 4311 - 4311
Опубликована: Окт. 13, 2022
Since the third scientific and technological revolution, electronic information technology has developed rapidly, piezoelectric materials that can convert mechanical energy into electrical have become a research hotspot. Among them, polymers are widely used in various fields such as water treatment, biomedicine, flexible sensors due to their good flexibility weak toxicity. However, compared with ceramic materials, properties of poor, so it is very important improve polymers. Electrospinning by adjusting electrospinning parameters control piezoelectrically active phase transition In addition, prepared nanofibrous membrane also substrate for supporting functional particles, which effectively doping particles. This paper reviews electrospun polymer membranes, especially polyvinylidene fluoride (PVDF)-based membranes (NFs). Additionally, this introduces methods increasing from perspective structure species. Finally, applications NFs biology, energy, photocatalysis discussed, future directions development prospected.
Язык: Английский
Процитировано
94
Polymers, Год журнала: 2023, Номер 15(4), С. 921 - 921
Опубликована: Фев. 12, 2023
Electrospun porous nanofibers have gained a lot of interest recently in various fields because their adjustable structure, high specific surface area, and large number active sites, which can further enhance the performance materials. This paper provides an overview common polymers, preparation, applications electrospun nanofibers. Firstly, polymers commonly used to construct structures main pore-forming methods by electrospinning, namely template method phase separation method, are introduced. Secondly, recent air purification, water treatment, energy storage, biomedicine, food packaging, sensor, sound wave absorption, flame retardant, heat insulation reviewed. Finally, challenges possible research directions for future study discussed.
Язык: Английский
Процитировано
79
Polymers, Год журнала: 2022, Номер 14(19), С. 3990 - 3990
Опубликована: Сен. 23, 2022
Electrospun porous nanofibers have large specific surface areas and abundant active centers, which can effectively improve the properties of nanofibers. In field photocatalysis, electrospun increase contact area loaded photocatalytic particles with light, shorten electron transfer path, activity. this paper, main pore−forming mechanisms nanofiber are summarized as breath figures, phase separation (vapor−induced separation, non−solvent−induced thermally induced separation) post−processing (selective removal). Then, application loading in degradation pollutants (such organic, inorganic, bacteria) water is introduced, its future development prospected. Although structures beneficial improving performance nanofibers, they reduce their mechanical properties. Therefore, strategies for also briefly discussed.
Язык: Английский
Процитировано
77
Biomolecules, Год журнала: 2023, Номер 13(1), С. 184 - 184
Опубликована: Янв. 16, 2023
Herbal medicine has a long history of medical efficacy with low toxicity, side effects and good biocompatibility. However, the bioavailability extract raw herbs bioactive compounds is poor because their water solubility. In order to overcome solubility issues, electrospinning technology can offer delivery alternative resolve them. The electrospun fibers have advantages high specific surface area, porosity, excellent mechanical strength flexible structures. At same time, various natural synthetic polymer-bound mimic extracellular matrix applications in different fields. this paper, development polymers used for incorporating herbal into nanofibers are reviewed. Finally, recent progress these biomedical (drug delivery, wound dressing, tissue engineering) food fields along future prospects discussed.
Язык: Английский
Процитировано
60
Journal of Pharmaceutical Sciences, Год журнала: 2023, Номер 112(11), С. 2719 - 2723
Опубликована: Авг. 27, 2023
Язык: Английский
Процитировано
51
Biomaterials Advances, Год журнала: 2023, Номер 150, С. 213404 - 213404
Опубликована: Март 31, 2023
Язык: Английский
Процитировано
44
Frontiers in Bioengineering and Biotechnology, Год журнала: 2024, Номер 12
Опубликована: Фев. 5, 2024
Diabetic wounds are a significant subset of chronic characterized by elevated levels inflammatory cytokines, matrix metalloproteinases (MMPs), and reactive oxygen species (ROS). They also associated with impaired angiogenesis, persistent infection, high likelihood hospitalization, leading to substantial economic burden for patients. In severe cases, amputation or even mortality may occur. foot ulcers (DFUs) common complication diabetes, up 25% diabetic patients being at risk developing over their lifetime, more than 70% ultimately requiring amputation. Electrospun scaffolds exhibit structural similarity the extracellular (ECM), promoting adhesion, growth, migration fibroblasts, thereby facilitating formation new skin tissue wound site. The composition size electrospun can be easily adjusted, enabling controlled drug release through fiber structure modifications. porous nature these facilitates gas exchange absorption exudate. Furthermore, surface readily modified impart specific functionalities, making electrospinning nanofiber highly promising treatment wounds. This article provides concise overview healing process in normal pathological mechanisms underlying wounds, including complications such as ulcers. It explores advantages treatment. Additionally, it summarizes findings from various studies on use different types reviews methods loading onto scaffolds. These advancements broaden horizon effectively treating
Язык: Английский
Процитировано
38
RSC Advances, Год журнала: 2024, Номер 14(5), С. 3359 - 3378
Опубликована: Янв. 1, 2024
Electrostatic spinning as a technique for producing nanoscale fibers has recently attracted increasing attention due to its simplicity, versatility, and loadability.
Язык: Английский
Процитировано
37