Frontiers in Neuroscience,
Год журнала:
2024,
Номер
18
Опубликована: Март 15, 2024
Introduction
Acupuncture
analgesia
(AA)
is
widely
used
in
clinical
practice.
The
autonomic
nervous
system
(ANS)
may
be
an
important
pathway
for
acupuncture
signal
transduction.
However,
real-time
changes
function
during
AA
and
the
effect
of
“needle
sensation”
remain
unclear.
Methods
We
established
a
human
pain
model
healthy
adults
randomly
assigned
128
participants
to
model,
sham
acupuncture,
groups
1:1:2
ratio.
Heart
rate
variability
(HRV),
including
total
power
(TP),
low-frequency
(LF),
high-frequency
(HF),
ratio
LF
HF
(LF/HF),
standard
deviation
normal-normal
intervals
(SDNN),
root
mean
square
successive
interval
differences
(RMSSD),
were
assess
function.
visual
analog
scale
(VAS)
efficiency
analgesic
acupuncture.
Massachusetts
General
Hospital
sensation
(MASS)
was
indicate
intensity
needle
sensation.
Anxiety
levels
also
measured.
Finally,
correlation
MASS
with
HRV,
VAS,
anxiety
analyzed.
Results
VAS
decreased
after
10
min
needling
5
withdrawal
group
compared
those
(
p
=
0.038,
0.020).
efficacy
rates
82.0,
50.0,
61.3%
groups,
respectively.
These
represent
significant
between
<
0.001
each
case).
No
observed
groups.
HF,
TP,
SDNN,
RMSSD
all
increased
0.045,
0.041,
0.002,
0.006,
respectively).
0.632,
0.542,
0.093,
0.222,
LF/HF
did
not
differ
among
three
A
positive
2
,
4
TP
5,
levels.
Conclusion
associated
enhanced
vagal
activity.
positively
correlated
sympathetic
nerve
activities.
effective
means
regulating
function,
modulator.
Frontiers in Immunology,
Год журнала:
2023,
Номер
14
Опубликована: Апрель 6, 2023
The
system
physiology
approaches
that
emerge
in
western
countries
recent
years
echo
the
holistic
view
of
ancient
Traditional
Chinese
Medicine
(TCM)
practices
deal
with
root,
rather
than
only
symptoms
diseases.
Particularly,
TCM
practices,
including
acupuncture,
emphasize
mobilization
self-healing
mechanisms
to
bring
back
body
homeostasis.
Acupuncture
has
been
practiced
for
over
two
thousand
modulate
via
stimulation
at
specific
regions
(acupoints).
With
development
various
research
on
acupuncture
therapy,
its
regulatory
effect
immune
gradually
recognized,
especially
immunological
diseases,
infectious
and
allergic
In
this
study,
we
reviewed
immunomodulatory
mechanism
systematically
integrates
existing
respectively
elucidate
modulatory
innate
system,
adaptive
well-known
neuroanatomical
mechanisms,
intact
somatosensory-autonomic
reflex
pathway.
advances
made
systems
studies,
now
have
a
great
opportunity
gain
insight
into
how
modulates
immunity,
subsequently
improves
efficacy.
Frontiers in Endocrinology,
Год журнала:
2023,
Номер
14
Опубликована: Май 16, 2023
Polycystic
ovary
syndrome
(PCOS)
is
a
reproductive
endocrine
disease
characterized
by
menstrual
disorders,
infertility,
and
obesity,
often
accompanied
insulin
resistance
metabolic
disorders.
The
pathogenesis
of
PCOS
relatively
complex
has
certain
relationship
with
increase
androgen
luteinizing
hormone
(LH)
the
main
cause
series
symptoms.
Traditional
Chinese
medicine
(TCM)
obvious
advantages
significant
curative
effects
in
treatment
this
disease.
It
can
effectively
reduce
level
patients,
regulate
lipid
metabolism,
ovulation
rate
pregnancy
fewer
side
effects.
This
article
reviews
efficacy
safety
herbs
other
TCM
(such
as
acupuncture)
its
complications
recent
years,
well
effect
mechanism
on
cellular
endocrine,
order
to
provide
new
clinical
idea
for
PCOS.
Frontiers in Neuroscience,
Год журнала:
2024,
Номер
18
Опубликована: Май 3, 2024
Deqi
is
an
important
prerequisite
for
acupuncture
to
achieve
optimal
efficacy.
Chinese
medicine
has
long
been
concerned
with
the
relationship
between
and
clinical
efficacy
of
acupuncture.
However,
underlying
mechanisms
are
complex
there
a
lack
systematic
summaries
objective
quantitative
studies
.
Acupuncture
can
purpose
treating
diseases
by
regulating
interaction
local
neighboring
acupoints,
brain
centers,
target
organs.
At
change
their
tissue
structure,
temperature,
blood
perfusion,
energy
metabolism,
electrophysiological
indicators.
central
level,
activate
regions
thalamus,
parahippocampal
gyrus,
postcentral
insular,
middle
temporal
cingulate
etc.
It
also
extensive
effects
on
limbic-paralimbic-neocortical-network
default
mode
network.
The
vary
depending
techniques
points
chosen.
In
addition,
's
mechanism
action
involves
correcting
abnormalities
in
multi-targeted
multi-layered.
biological
closely
related
centers.
This
study
will
help
explore
from
local-central-target-organ
perspective
provide
information
future
decision-making.
BMC Complementary Medicine and Therapies,
Год журнала:
2024,
Номер
24(1)
Опубликована: Авг. 21, 2024
Insomnia
disorder
(ID)
is
one
of
the
most
common
sleep
problems,
usually
accompanied
by
anxiety
and
depression
symptoms.
Functional
magnetic
resonance
imaging
(fMRI)
study
suggests
that
both
poor
quality
negative
emotion
are
linked
to
dysregulation
brain
network
related
processing
in
ID
patients.
Acupuncture
therapy
has
been
proven
effective
improving
mood
patients,
but
involved
neurobiological
mechanism
remains
unclear.
We
aimed
investigate
modulation
effect
acupuncture
on
resting-state
functional
connectivity
(rsFC)
emotional
(EN)
patients
experiencing
insomnia.
A
total
30
healthy
controls
(HCs)
60
were
enrolled
this
study.
Sixty
randomly
assigned
real
sham
groups
attended
fMRI
scans
before
after
4
weeks
treatment.
HCs
completed
an
MRI/fMRI
scan
at
baseline.
The
rsFC
values
within
EN
calculated,
Hamilton
Anxiety
Scale
(HAMA),
Depression
(HAMD),
Pittsburgh
Sleep
Quality
Index
(PSQI),
Hyperarousal
(HAS),
actigraphy
data
collected
for
clinical
efficacy
evaluation.
Resting-state
FC
analysis
showed
abnormalities
centered
thalamus
dorsolateral
prefrontal
cortex
compared
HCs.
After
treatment,
anterior
cingulate
cortex,
hippocampus,
amygdala
increased
with
group
(p
<
0.05,
FDR
corrected).
In
group,
value
was
decreased
between
left
treatment
trend
correlation
found
right
hippocampus
positively
correlated
HAMA
scores
across
all
negatively
efficiency
group.
Our
findings
could
produce
a
positive
modulating
which
may
illustrate
central
underlying
insomnia
regulation.
http://www.chictr.org.cn
.,
ChiCTR1800015282,
20/03/2018.
Abstract
Lack
of
liver
regenerative
capacity
is
the
primary
cause
hepatic
failure
and
even
mortality
in
patients
undergoing
hepatectomy,
with
no
effective
intervention
strategies
currently
available.
Therefore,
identifying
efficacious
interventions
to
enhance
regeneration
pivotal
for
optimizing
clinical
outcomes.
Recent
studies
have
demonstrated
that
vagotomy
exerts
an
inhibitory
effect
on
following
partial
thereby
substantiating
role
played
by
vagus
nerve
process
regeneration.
In
recent
years,
electroacupuncture
(EA)
has
emerged
as
a
non‐invasive
technique
stimulating
nerve.
However,
EA
remains
uncertain.
this
study,
70%
hepatectomy
(PH)
mouse
model
utilized
investigate
effects
acute
elucidate
its
underlying
molecular
mechanisms.
It
observed
at
ST36
acutely
activated
cholinergic
neurons
dorsal
motor
nucleus
(DMV),
resulting
increased
release
acetylcholine
from
vagal
endings
subsequent
activation
IL‐6
signaling
macrophages.
Ultimately,
these
events
promoted
hepatocyte
proliferation
facilitated
These
findings
provide
insights
into
fundamental
brain‐liver
axis
mechanism
through
which
promotes
regeneration,
offering
novel
therapeutic
approach
post‐hepatectomy
disorders.
Scientific Reports,
Год журнала:
2024,
Номер
14(1)
Опубликована: Апрель 10, 2024
Abstract
To
maintain
current
cognitive
function
and
access
greater
reserves,
nonpharmacological
interventions
may
be
a
viable
alternative
for
older
adults
with
or
without
impairment.
This
study
aimed
to
compare
different
enhancing
global
cognition,
including
mind–body
exercise,
physical
non-invasive
brain
stimulation,
training
intervention
(CTI),
acutherapy
(ACU),
meditation,
music
therapy,
by
applying
network
meta-analysis
(NMA).
Sixty-one
randomized
controlled
trials
evaluating
the
efficacy
of
on
cognition
in
mild
decline
were
selected.
An
NMA
was
conducted
interventions.
The
revealed
that
exercise
(standardized
mean
difference,
1.384;
95%
confidence
interval,
0.777–1.992);
ACU
(1.283;
0.478–2.088);
meditation
(0.910;
0.097–1.724);
stimulation
(1.242;
0.254–2.230);
CTI
(1.269;
0.736–1.802);
(0.977;
0.212–1.742),
showed
positive
effects
compared
passive
controls.
There
no
significant
differences
between
efficacies
other
Nonpharmacological
potentially
enhance
through
various
pathways,
such
as
memorizing
movements
plasticity
reducing
stress
adult
population.
Additional
studies
are
needed
clarify
impact
variables,
methods
psychological
variables.
Journal of Multidisciplinary Healthcare,
Год журнала:
2024,
Номер
Volume 17, С. 3459 - 3473
Опубликована: Июль 1, 2024
Abstract:
Cardiovascular
diseases
(CVDs)
are
increasingly
prevalent
in
clinical
settings.
With
the
continuous
improvement
of
people's
living
standards,
gradual
acceleration
pace
life,
and
deterioration
environment
recent
years,
incidence
CVDs
is
increasing
annually.
The
prevalence
among
individuals
aged
50
above
notably
elevated,
posing
a
significant
risk
to
patients'
well-being
lives.
At
this
juncture,
numerous
treatment
choices
available
for
managing
CVDs,
with
traditional
Chinese
medicine
(TCM)
therapy
standing
out
as
practical,
safe,
reliable
option.
Over
there
has
been
growing
acknowledgement
both
medical
professionals
patients.
expanding
integration
TCM
various
conditions,
use
gained
attention
within
community,
potentially
emerging
an
efficacious
approach
addressing
cardiovascular
diseases.
This
article
conducts
comprehensive
review
approach,
particularly
acupuncture,
supplementary
highlighting
its
ability
effectively
lower
blood
pressure,
decrease
coronary
artery
events,
mitigate
arrhythmias,
enhance
cardiac
function
when
used
alongside
conventional
medication.
underscores
promise
acupuncture
enhancing
health,
although
variations
research
methodologies
necessitate
standardized
applications.
Keywords:
diseases,
medicine,
Olanzapine-induced
weight
gain
and
disruptions
in
lipid
metabolism
represent
multifactorial
processes
that
compromise
treatment
adherence
schizophrenia
contribute
to
substantial
clinical
challenges.
While
acupuncture
has
been
reported
promote
loss,
the
neural
substrates
mediating
its
metabolic
effects
olanzapine-induced
models
remain
largely
undefined.
In
this
study,
we
evaluated
efficacy
of
electroacupuncture
(EA)
at
Zusanli
(ST36)
acupoint
ameliorating
obesity
dyslipidemia,
investigated
underlying
liver-brain
regulatory
mechanisms.
We
further
assessed
EA
through
Reverse
Transcription
Polymerase
Chain
Reaction
(RT-PCR),
ELISA,
lipidomics
analysis.
Comprehensive
evaluations
were
conducted
using
three-dimensional
fine
behavioral
analysis
cages.
Additionally,
ultrasound
functional
imaging
(fUS),
retrograde
tracing
with
pseudorabies
virus
152
(PRV152),
c-Fos
mapping
techniques
employed
investigate
interactions.
ST36
effectively
reduced
body
weight,
reversed
adipocyte
hypertrophy
hepatocyte
damage,
restored
disturbances
free
fatty
acids
(FFA)
liver
metabolism.
These
also
involved
restoration
respiratory
exchange
rate
(RER)
during
dark
cycle.
explored
potential
mechanisms,
successfully
demonstrated
stimulation
significantly
deactivated
Agouti-related
protein
(AGRP)-expressing
neurons
lateral
septal
nucleus
(LS),
accumbens
(NAc),
pallidum,
suggesting
AGRP+
these
brain
regions
are
interaction
treatment.
findings
highlight
critical
role
metabolism-regulating
acupuncture-mediated
axis
provide
insights
into
mechanisms
information
integration
from
liver.