Heliyon,
Год журнала:
2023,
Номер
10(1), С. e23370 - e23370
Опубликована: Дек. 26, 2023
Phellinus
spp.
have
historically
been
used
as
traditional
medicines
to
treat
various
diseases
owing
their
antioxidant,
antitumor,
and
antidiabetic
activities.
Polysaccharides
exhibit
activity.
In
the
present
study,
polysaccharide
contents
of
four
strains
were
compared.
igniarius
QB72
possessed
higher
production,
stronger
2,2-diphenyl-1-picrylhydrazyl
(DPPH)
radical
scavenging,
α-amylase
inhibitory
The
three
polysaccharides
sequentially
extracted
partially
purified
from
fermentation
mycelia
using
hot
water,
1
%
(NH4)2C2O4,
1.25
M
NaOH.
Hot
water
extract
exhibited
DPPH
scavenging
strong
activity
against
with
an
IC50
value
6.84
±
0.37
mg/mL.
carbohydrate
content
A1
(approximately
17457
Da)
was
approximately
88.28
%.
decreased
(3.178
0.187
mg/mL)
after
DEAE
elution.
P.
hot-water
extracts
great
potential
inhibitors
in
food
medication-assisted
additives.
Food Chemistry X,
Год журнала:
2024,
Номер
23, С. 101774 - 101774
Опубликована: Авг. 25, 2024
In
recent
years,
the
global
mushroom
industry
has
seen
remarkable
growth
due
to
its
nutritional
benefits,
increasing
market
value,
and
rising
consumer
demand.
Mushrooms
are
valued
for
their
unique
flavor,
low
sugar
salt,
rich
Vitamin
D
content.
India
as
well
across
globe,
cultivation
is
becoming
increasingly
popular
among
new
entrepreneurs,
leveraging
diverse
agro-climatic
conditions
substantial
agricultural
waste.
Various
government
policies
also
fostering
research
development
in
this
sector.
To
extend
shelf
life
preserve
quality,
various
preservation
techniques
employed,
including
drying,
freezing,
canning,
high-pressure
processing
modified
atmosphere
packaging.
Furthermore,
cutting-edge
technologies
such
nuclear
magnetic
resonance
spectroscopy
improving
post-harvest
processing,
helping
maintain
sensory
properties
Automation
transforming
by
enhancing
efficiency
scalability.
This
review
examines
innovative
methods
driving
advancements
production
quality
worldwide.
Fitoterapia,
Год журнала:
2023,
Номер
172, С. 105681 - 105681
Опубликована: Сен. 23, 2023
Resistance
to
apoptosis
stands
as
a
roadblock
the
successful
pharmacological
execution
of
anticancer
drug
effect.
A
comprehensive
insight
into
apoptotic
signaling
pathways
and
an
understanding
mechanisms
resistance
are
crucial
unveil
new
targets.
At
this
juncture,
researchers
heading
towards
natural
sources
in
particular,
mushroom
their
potential
drugs
leads
being
reliable
source
potent
bioactive
compounds.
Given
continuous
increase
cancer
cases,
efficacy
mushrooms
has
inevitably
become
fascinating
object
due
higher
safety
margin
multitarget.
This
review
aimed
collect
summarize
all
available
scientific
data
on
with
from
extracts
molecules
order
suggest
attributes
via
mitochondrion
-mediated
intrinsic
mechanism.
Compiled
revealed
that
components
including
polysaccharides,
sterols
terpenoids
well
prepared
using
15
different
solvents
53
species
could
be
effective
supportive
treatment
20
various
cancers.
The
underlying
therapeutic
studied
explored
through
diverse
complementary
investigations:
vitro
assays,
pre-clinical
studies
clinical
randomized
controlled
trials.
processes
mainly
involved
were
ROS
production,
mitochondrial
membrane
dysfunction,
action
caspase
3,
9,
XIAP,
cIAP,
p53,
Bax,
Bcl-2.
In
summary,
study
provides
facts
pertaining
beneficial
effect
active
compounds
against
types
is
shedding
light
targeted
pathways.
New Zealand Journal of Botany,
Год журнала:
2024,
Номер
unknown, С. 1 - 85
Опубликована: Июль 22, 2024
Ganoderma,
a
genus
of
mushrooms
known
for
its
long
history
medicinal
use,
has
gained
increasing
attention
in
recent
years
due
to
potential
health
benefits.
This
review
delves
into
the
bioactive
compounds
found
Ganoderma
and
elucidates
intricate
mechanisms
underlying
immunomodulatory
anti-tumour
activities.
The
diverse
health-promoting
effects
can
be
attributed
decadent
array
compounds,
notably
polysaccharides,
triterpenoids,
which
play
pivotal
role.
ability
mushroom
modulate
immune
system,
enhancing
activity
cells,
such
as
natural
killer
cells
macrophages,
is
central
focus.
Furthermore,
we
explore
how
exerts
through
induction
apoptosis,
inhibition
angiogenesis,
interference
with
various
signalling
pathways
critical
cancer
cell
growth
metastasis.
As
research
this
area
continues
evolve,
comprehensive
understanding
supplement
role
promoting
well-being
emerging,
offering
promising
avenues
further
investigation
application
healthcare.
Journal of Fungi,
Год журнала:
2024,
Номер
10(6), С. 394 - 394
Опубликована: Май 31, 2024
This
review
evaluates
the
therapeutic
effects
of
polysaccharides
derived
from
mushroom
species
that
have
medicinal
and
edible
properties.
The
fungal
were
recently
studied,
focusing
on
their
modulation
gut
microbiota
impact
various
diseases.
study
covers
both
clinical
preclinical
studies,
detailing
results
highlighting
significant
influence
these
modulation.
It
discusses
potential
health
benefits
incorporating
into
diet
for
managing
chronic
diseases
such
as
diabetes,
neurodegenerative
disorders,
cancer.
Furthermore,
emphasizes
interaction
between
microbiota,
underscoring
role
in
modulating
microbial
community.
presents
a
systematic
analysis
findings,
demonstrating
substantial
composition
function,
which
may
contribute
to
conditions.
We
conclude
by
play
crucial
mediating
effects,
offering
promising
avenue
further
research
applications
disease
prevention
treatment.
International Journal of Analytical Chemistry,
Год журнала:
2023,
Номер
2023, С. 1 - 20
Опубликована: Сен. 22, 2023
Secondary
metabolites
are
hidden
gems
in
mushrooms.
Understanding
these
secondary
metabolites'
biological
and
pharmacological
effects
can
be
aided
by
identifying
them.
The
purpose
of
this
work
was
to
profile
the
mycochemical
components
extracts
Auricularia
auricula
judae,
Microporus
xanthopus,
Termitomyces
umkowaani,
Trametes
elegans,
versicolor
comprehend
their
capabilities.
Mushroom
samples
were
collected
from
Kenya's
Arabuko-Sokoke
Kakamega
National
Reserved
Forests
identified
using
morphological
molecular
techniques.
Chloroform,
70%
ethanol,
hot
water
solvents
used
extract
components.
Gas
chromatography
mass
spectrometry
(GC-MS)
analyze
chloroform,
all
species
examined.
A
total
51
compounds
isolated
classified
as
carboxylic
acids,
esters,
phenols,
fatty
alcohol,
epoxides,
aldehydes,
isoprenoid
lipids,
steroids.
Tetracosamethyl-cyclododecasiloxane
(18.90%),
oleic
acid
(72.90%),
phenol,
2,
6-bis
(1,
1-dimethylethyl)-4-methyl-,
methylcarbamate
(26.56%)
found
high
concentrations
A.
auricular
M.
T.
versicolor,
respectively.
Fatty
acids
make
up
majority
elegans
chloroform
umkowaani
ethanol
extract,
Particularly,
play
crucial
roles
anti-inflammatory,
hypocholesterolemic,
anticancer,
antibiofilm
formation
activities.
These
bioactive
elements
indicate
that
five
wild
mushrooms
may
reliable
sources
for
therapeutic
development.
Therefore,
additional
research
is
required
usefulness
chemicals
many
functional
areas
improve
present
understanding
macrofungi.
