Predictive Modeling and Integrated Risk Assessment of Postoperative Mortality and Pneumonia in Traumatic Brain Injury Patients through Clustering and Machine Learning: Retrospective Study DOI Creative Commons
Jong Ho Kim,

Kyung-Min Chung,

Jaejun Lee

и другие.

Biomedicines, Год журнала: 2023, Номер 11(11), С. 2880 - 2880

Опубликована: Окт. 24, 2023

This study harnessed machine learning to forecast postoperative mortality (POM) and pneumonia (PPN) among surgical traumatic brain injury (TBI) patients. Our analysis centered on the following key variables: Glasgow Coma Scale (GCS), midline shift (MSB), time from emergency room arrival (TIE). Additionally, we introduced innovative clustered variables enhance predictive accuracy risk assessment. Exploring data 617 patients spanning 2012 2022, observed that 22.9% encountered mortality, while 30.0% faced (PPN). Sensitivity for POM PPN prediction, before incorporating clustering, was in ranges of 0.43-0.82 0.54-0.76 Following sensitivity values were 0.47-0.76 0.61-0.77 Accuracy 0.67-0.76 0.70-0.81 prior clustering 0.42-0.73 0.55-0.73 after clustering. Clusters characterized by low GCS, small MSB, short TIE exhibited a 3.2-fold higher compared clusters with high TIE. In summary, leveraging offers novel avenue predicting TBI Assessing amalgamated impact characteristics provides valuable insights clinical decision making.

Язык: Английский

Impact of preoperative inflammatory biomarkers on postoperative pneumonia and one-month pulmonary imaging changes after surgery for non-small cell lung cancer DOI Creative Commons

Yingding Ruan,

Wenjun Cao,

Jianwei Han

и другие.

Frontiers in Oncology, Год журнала: 2025, Номер 15

Опубликована: Март 18, 2025

This study examined the effectiveness of preoperative inflammatory markers in predicting occurrence postoperative pneumonia (POP) and clinical outcomes based on chest computed tomography (CT) images patients who underwent surgical resection for non-small cell lung cancer (NSCLC). retrospective included NSCLC surgery at The First People's Hospital Jiande between January 2019 October 2023. Data demographic characteristics, biomarkers, approach duration, outcomes, CT findings 1 month postoperatively were collected analyzed. POP after was assessed using propensity score matching. Among 568 patients, 72 (12.7%) had POP. After matching, 252 (POP group: 66; non-POP 186) analysis. systemic immune-inflammation index (SII) platelet-to-lymphocyte ratio (PLR) significantly higher group than (433.53 vs. 323.75, P = 0.001; 126.42 103.64, < 0.001). length hospital stay percentage improved clinically (11 days 9 days, 0.008; 77.3% 59.7%, 0.033). Multivariate analysis showed that PLR lymphocyte-to-monocyte (LMR) independent predictors (AUC 0.780 0.730, both However, there no significant differences radiographic among stratified by risk LMR accurately predict with NSCLC. Nonetheless, these ratios may not resection.

Язык: Английский

Процитировано

0
Nomogram prediction model of postoperative pneumonia in patients with lung cancer: A retrospective cohort study DOI Creative Commons

Fan Jin,

Wei Liu, Xi Qiao

и другие.

Frontiers in Oncology, Год журнала: 2023, Номер 13

Опубликована: Фев. 23, 2023

The prediction model of postoperative pneumonia (POP) after lung cancer surgery is still scarce.Retrospective analysis patients with who underwent at Fourth Hospital Hebei Medical University from September 2019 to March 2020 was performed. All were randomly divided into two groups, training cohort and validation the ratio 7:3. nomogram formulated based on results multivariable logistic regression clinically important factors associated POP. Concordance index (C-index), receiver operating characteristic (ROC) curve, calibration Hosmer-Lemeshow goodness-of-fit test decision curve (DCA) used evaluate predictive performance nomogram.A total 1252 enrolled, including 877 cases in 375 cohort. POP found 201 (22.9%) 89 (23.7%) cohorts, respectively. consisted six variables, smoking, diabetes mellitus, history preoperative chemotherapy, thoracotomy, ASA grade time. C-index AUC 0.717 (95%CI:0.677-0.758) 0.726 (95%CI:0.661-0.790) curves showed had good agreement. result DCA that clinical benefits.This proposed could predict risk advance, which can help clinician make reasonable preventive treatment measures.

Язык: Английский

Процитировано

9
Associated Factors of Pneumonia in Individuals with Chronic Obstructive Pulmonary Disease (COPD) Apart from the Use of Inhaled Corticosteroids DOI Creative Commons

Rosario Lineros,

Lourdes Fernández-Delgado,

Antonio Pereira Vega

и другие.

Biomedicines, Год журнала: 2023, Номер 11(5), С. 1243 - 1243

Опубликована: Апрель 22, 2023

Inhaled corticosteroids (ICSs) are widely used in chronic obstructive pulmonary disease (COPD) and combination with long-acting β2 agonists (LABAs) to reduce exacerbations improve patient lung function quality of life. However, ICSs have been associated an increased risk pneumonia individuals COPD, although the magnitude this remains unclear. Therefore, it is difficult make informed clinical decisions that balance benefits adverse effects people COPD. There may be other causes patients these not always considered studies on risks using We consider very useful clarify aspects assessing influence incidence their role treatment This issue has important implications for current practice evaluation management since COPD benefit from specific ICS-based strategies. Many potential can act synergistically, so they included more than one section.

Язык: Английский

Процитировано

9
Diagnostic value of systematic bronchial aspirate on postoperative pneumonia after pulmonary resection surgery for lung cancer: a monocentre retrospective study DOI Creative Commons
Olivier Georges, Osama Abou‐Arab,

Malek Ben Rahal

и другие.

Interdisciplinary CardioVascular and Thoracic Surgery, Год журнала: 2024, Номер 38(2)

Опубликована: Фев. 1, 2024

Abstract OBJECTIVES Intraoperative bacterial airway colonization seems to be associated with an increased risk of postoperative pneumonia (POP). It can easily assessed by performing a bronchial aspirate (BA). The objective this study is assess the diagnostic performance BA predict POP. METHODS We conducted single-centre retrospective observational over period 10 years, from 1 January 2011 30 December 2020. population included patients admitted for scheduled pulmonary resection surgery lung cancer. Patients were classified into 2 populations depending on whether or not they developed Uni- and multivariable analyses performed identify factors developing was represented its sensitivity, specificity positive negative predictive values. RESULTS A total 1006 in study. found that independently greater POP odds ratio 6.57 [4.165–10.865]; P &lt; 0.001. Its 95%, sensitivity 31%, value 66% 81%. CONCLUSIONS intraoperative independent factor after cancer surgery. Further trials are required validate systematic implementation as early tool

Язык: Английский

Процитировано

2
Impact of preoperative inflammatory indices and postoperative pneumonia on postoperative atrial fibrillation in patients with non-small cell lung cancer: a retrospective study DOI Creative Commons

Yingding Ruan,

Jianwei Han,

Aiming Yang

и другие.

BMC Pulmonary Medicine, Год журнала: 2024, Номер 24(1)

Опубликована: Июль 23, 2024

Abstract Background This study aimed to evaluate the impact of preoperative inflammatory indices and postoperative pneumonia (POP) on atrial fibrillation (POAF) in non–small cell lung cancer (NSCLC) patients. Methods All consecutive patients who underwent pulmonary resection at our hospital (January 2016-October 2019) were enrolled. Preoperative indices, demographic data, surgical details, conditions analyzed. Univariate multivariate analyses risk factors associated with POAF also conducted. Results Among 382 included study, 32 (8.38%) developed POAF. Compared non-POAF patients, had greater incidence POP ( P = 0.09). Approximately 31 (96.9%) within three days after surgery. The group a significantly mean age (68.94 years) than did (63 0.002). Additionally, compared exhibited an increased number resected mediastinal lymph nodes < 0.001) node stations 0.001).The intraoperative blood volume 0.006), longer duration 0.022), drainage 0.003). IA/B stage IIIA/B stage( 0.001), lobectomy 0.008) wedge 0.023) those group, stays (10.54 vs. 9 days; times (7 5 0.004). Multivariate analysis revealed age, POP, as independent influencing NSCLC Conclusion not POAF, but identified factors. Advanced-stage may have susceptibility early-stage although further validation is needed. was linked stay.

Язык: Английский

Процитировано

2
The (un)lucky seven—how can we mitigate risk factors for postoperative pneumonia after lung resections? DOI Open Access
Koen Verkoulen, Iris E. W. G. Laven, Jean H. T. Daemen

и другие.

Translational Lung Cancer Research, Год журнала: 2024, Номер 13(8), С. 1763 - 1767

Опубликована: Авг. 1, 2024

Язык: Английский

Процитировано

1
External validation of the CARDOT score for predicting respiratory complications after thoracic surgery DOI Creative Commons
Tanyong Pipanmekaporn,

Pakaros Kitswat,

Prangmalee Leurcharusmee

и другие.

BMC Anesthesiology, Год журнала: 2024, Номер 24(1)

Опубликована: Авг. 30, 2024

Язык: Английский

Процитировано

1
Minimally invasive surgery, precise anesthesia and effective analgesia are crucial for walking within 1 hour after lung surgery DOI Open Access

Dan Lu,

Chao Zhou, Yiwen Zhang

и другие.

Journal of Thoracic Disease, Год журнала: 2024, Номер 16(9), С. 5792 - 5801

Опубликована: Сен. 1, 2024

The clinical effectiveness of enhanced recovery after surgery (ERAS) strategy, which emphasizes a comprehensive intervention without highlighting key points, seems to have reached bottleneck. This study focuses on surgery, anesthesia and postoperative analgesia as the three factors, observe related manifestations ERAS in patients undergoing lung with minimal throughout perioperative period.

Язык: Английский

Процитировано

1
Development and validation of a nomogram for predicting pulmonary complications in elderly patients undergoing thoracic surgery DOI Creative Commons

Jingjing Liu,

Dinghao Xue, Long Wang

и другие.

Aging Clinical and Experimental Research, Год журнала: 2024, Номер 36(1)

Опубликована: Окт. 5, 2024

Язык: Английский

Процитировано

1
The association between double-lumen tube versus bronchial blocker and postoperative pulmonary complications in patients after lung cancer surgery DOI Creative Commons
Wei Liu,

Fan Jin,

Hemei Wang

и другие.

Frontiers in Oncology, Год журнала: 2022, Номер 12

Опубликована: Сен. 27, 2022

Both double-lumen tube (DLT) and bronchial blocker (BB) are used for lung isolation in patients undergoing cancer surgery. However, the effects of different devices remain inconclusive. Present study was designed to investigate association between choice two postoperative pulmonary complications (PPCs) with cancer.In this retrospective cohort study, who underwent surgery January 1, 2020 October 31, were screened. Patients divided into groups according isolation: DLT group BB group. Primary outcome incidence a composite PPCs during in-hospital stay.A total 1721 enrolled analysis, them, 868 received 853 BB. A less common (25.1%, [214/853]) than those (37.9% [329/868] OR 0.582 95% CI 0.461-0.735 P < 0.001). Respiratory infection (14.4%, [123/853]) (30.3%, [263/868], P<0.001). The non-PPCs not statistically significant 2 groups.For cancer, use associated reduced risk when compared DLT.

Язык: Английский

Процитировано

6