Critical Reviews in Microbiology,
Год журнала:
2025,
Номер
unknown, С. 1 - 26
Опубликована: Март 20, 2025
Vaccination
plays
a
critical
role
in
public
health
by
reducing
the
incidence
and
prevalence
of
infectious
diseases.
The
efficacy
vaccine
has
numerous
determinants,
which
include
age,
sex,
genetics,
environment,
geographic
location,
nutritional
status,
maternal
antibodies,
prior
exposure
to
pathogens.
However,
little
is
known
about
gut
microbiome
how
it
can
be
targeted
through
dietary
interventions
improve
immunological
responses.
Unveiling
this
link
imperative,
particularly
post-pandemic
world,
considering
impaired
COVID-19
response
observed
dysbiotic
individuals.
Therefore,
article
aims
comprehensively
review
diet
probiotics
modulate
composition,
linked
efficacy.
Dietary
fiber
polyphenolic
compounds
derived
from
plant-based
foods
microbial
diversity
promoting
growth
short-chain
fatty
acids-producing
microbes.
On
other
hand,
animal-based
have
mixed
effects
–
whey
protein
fish
oil
promote
eubiosis
In
contrast,
lard
red
meat
adverse
effects.
Studies
further
indicate
that
probiotic
supplements
exert
varied
effects,
mostly
strain
dosage-specific.
Interlinking
diet,
microbiome,
probiotics,
vaccines
will
reveal
opportunities
for
newer
research
on
diet-induced
microbiome-manipulated
precision
vaccination
strategies
against
International Journal of Molecular Sciences,
Год журнала:
2024,
Номер
25(9), С. 4769 - 4769
Опубликована: Апрель 27, 2024
Contemporary
living
is
continuously
leading
to
poor
everyday
choices
resulting
in
the
manifestation
of
various
diseases.
The
benefits
plant-based
nutrition
are
undeniable
and
research
on
topic
rising.
Modern
man
now
aware
possibilities
that
plant
can
provide
seeking
ways
benefit
from
it.
Dietary
phenolic
compounds
among
easily
accessible
beneficial
substances
exhibit
antioxidant,
anti-inflammatory,
antitumor,
antibacterial,
antiviral,
antifungal,
antiparasitic,
analgesic,
anti-diabetic,
anti-atherogenic,
antiproliferative,
as
well
cardio-and
neuroprotective
activities.
Several
industries
exploring
incorporate
biologically
active
their
produce.
This
review
concentrated
presenting
current
information
about
dietary
contribution
maintaining
good
health.
Additionally,
this
content
will
demonstrate
importance
prosperity
natural
for
fields,
i.e.,
food
industry,
cosmetology,
biotechnology,
others.
Foods,
Год журнала:
2025,
Номер
14(3), С. 495 - 495
Опубликована: Фев. 4, 2025
Lactic
acid
bacteria
(LAB)
constitute
a
heterogeneous
group
of
isolated
from
fermented
foods,
animals,
plants,
and
mammalian
guts,
with
many
health-promoting
properties.
Probiotics
antagonistic
properties
against
human
pathogens
foodborne
have
garnered
significant
attention
the
scientific
fraternity.
A
dedicated
review
focusing
on
plant-derived
probiotic
their
has
not
been
comprehensively
reviewed.
Thus,
this
aimed
at
providing
an
overview
LAB
isolates
derived
several
unconventional
sources
such
as
fruits,
seeds,
fruit
pulp,
leaves,
roots,
vegetables,
grasses,
flowers
antibacterial,
antifungal,
antiviral
This
paper
reviewed
antimicrobial
different
genera,
Lactobacillus,
Leuconostoc,
Weissella,
Enterococcus,
Pediococcus,
Bacillus,
Fructobacillus,
postbiotics,
paraprobiotics.
Several
important
mechanisms,
including
secretion
bacteriocins,
bacteriocin-like
substances,
reuterin,
organic
acids
(lactic
acetic),
peptides,
exopolysaccharides,
hydrogen
peroxide,
attributed
to
actions
pathogens.
However,
precise
mode
action
is
poorly
understood;
hence,
further
research
should
be
conducted
reveal
detailed
mechanisms.
Finally,
discusses
summary
future
implications.
Given
significance,
compounds
can
potentially
exploited
in
food
preservation
safety
or
for
medicinal
applications
after
evaluating
safety.
Molecular Nutrition & Food Research,
Год журнала:
2023,
Номер
68(1)
Опубликована: Окт. 27, 2023
Scope
This
study
aims
to
systematically
review
observational
studies
investigating
the
relation
between
dietary
(poly)phenol
consumption
and
various
cognitive
outcomes.
Methods
results
Embase
PubMed
databases
are
searched
from
inception
April
2023
for
intake
For
quantitative
analyses,
random
effects
models,
subgroup
dose–response
analyses
performed.
A
total
of
37
included
in
systematic
review.
Among
(poly)phenols,
a
higher
flavonoids
is
associated
with
better
function
lower
odds
decline
(although
some
exceptions).
meta‐analysis
shows
an
overall
inverse
association
impairment
reduced
incidence
dementia
or
related
disorders
(relative
risk
(RR)
=
0.83,
95%
confidence
interval
(CI):
0.76,
0.89),
anthocyanins
(RR
0.73,
CI:
0.60,
flavones
0.77,
0.63,
0.94),
flavan‐3‐ols
0.86,
0.82,
0.91),
flavonols
0.88,
0.80,
0.96).
Data
on
other
(poly)phenolic
compounds
(i.e.,
phenolic
acids)
promising
but
too
preliminary.
Conclusion
Habitual
inclusion
diet
may
play
preventive
role
against
disorders.
Food Bioscience,
Год журнала:
2023,
Номер
57, С. 103539 - 103539
Опубликована: Дек. 26, 2023
Benign
prostatic
hyperplasia
(BPH)
and
cancer
are
aging-associated
urological
conditions
in
men.
While
significant
advances
have
been
made
relation
to
treatment,
poor
response,
treatment
resistance
adverse
side-effects
limit
currently
available
therapies.
The
possible
antiproliferative
and/or
ameliorative
potentials
of
Juglans
regia
reported,
however,
there
is
a
dearth
scientific
information
on
its
effect
BPH
or
cancer.
In
this
study,
in-vivo
in-vitro
studies
were
used
assess
the
benefits
fresh
walnut
fruits
extract
prostate
High-performance
liquid
chromatography
coupled
with
electro
spray
ionization
quadrupole-time-of-flight
mass
spectrometry
(HPLC-ESI-Q-TOF)
was
chemical
profile
plant
extract.
anti-proliferative
activity
tested
against
normal
cancerous
human
cell
line
by
using
iCELLigence
real-time
label-free
analysis
system.
potential
assessed
administering
at
50
100
mg/kg
body
weight
rats
testosterone
induced
BPH.
Analysis
phytochemicals
revealed
high
concentration
phenolic
acids
flavonoids,
also
showing
time-
dose-dependent
cells,
reversed
biochemical
histomorphological
changes
testosterone-induced
Rheumatoid
arthritis
(RA)
is
a
complex
illness
with
both
hereditary
and
environmental
compo-nents.
Globally,
in
2019,
18
million
people
had
RA.
RA
characterised
by
persistent
inflammation
of
the
synovial
membrane
that
lines
joints,
cartilage
loss,
bone
erosion.
Phenolic
molecules
are
most
prevalent
secondary
metabolites
plants,
diverse
spectrum
biological
ac-tions
benefit
functional
meals
nutraceuticals.
These
compounds
have
received
lot
at-tention
recently
because
they
antioxidant,
anti-inflammatory,
immunomodulatory,
anti-rheumatoid
activity
modulating
tumour
necrosis
factor,
mitogen-activated
protein
kinase,
nu-clear
factor
kappa-light-chain-enhancer
activated
B
cells,
c-Jun
N-terminal
kinases,
as
well
other
preventative
properties.
This
article
discusses
dietary
polyphenols,
their
pharmacological
properties,
innovative
delivery
technologies
for
treatment
RA,
focus
on
possible
activities.
Nonetheless,
commercialization
polyphenols
may
be
achievable
only
after
confirming
safety
profile
completing
successful
clinical
trials.
Antioxidants,
Год журнала:
2024,
Номер
13(5), С. 514 - 514
Опубликована: Апрель 25, 2024
Sesame
seeds
are
important
resources
for
relieving
oxidation
stress-related
diseases.
Although
a
significant
variation
in
seeds’
antioxidant
capability
is
observed,
the
underlying
biochemical
and
molecular
basis
remains
elusive.
Thus,
this
study
aimed
to
reveal
major
seed
components
key
mechanisms
that
drive
variability
of
activity
(AOA)
using
panel
400
sesame
accessions.
The
AOA,
total
flavonoid,
phenolic
contents
varied
from
2.03
78.5%,
0.072
3.104
mg
CAE/g,
2.717
21.98
GAE/g,
respectively.
Analyses
revealed
flavonoids
acids
main
contributors
AOA
variation,
irrespective
coat
color.
LC-MS-based
polyphenol
profiling
high
(HA)
low
(LA)
uncovered
320
differentially
accumulated
compounds
(DAPs),
including
311
up-regulated
HA
seeds.
Tricin,
persicoside,
5,7,4′,5′-tetrahydro-3′,6-dimethoxyflavone,
8-methoxyapigenin,
6,7,8-tetrahydroxy-5-methoxyflavone
were
top
five
HA.
Comparative
transcriptome
analysis
at
three
developmental
stages
identified
627~2357
DEGs
unveiled
differential
regulation
flavonoid
biosynthesis,
phenylpropanoid
stilbene
biosynthesis
capacity
variation.
Major
regulated
structural
genes
transcription
factors
identified.
SINPZ0000571
(MYB),
SINPZ0401118
(NAC),
SINPZ0500871
(C3H)
most
highly
induced
TFs
Our
findings
may
enhance
quality
breeding.
