Journal of Nanomaterials,
Год журнала:
2024,
Номер
2024, С. 1 - 23
Опубликована: Янв. 8, 2024
Chronic
wounds,
which
include
venous
leg
ulcers,
diabetic
foot
and
pressure
are
a
global
health
issue
that
affects
between
1%
2%
of
the
developed
world’s
population.
wound
healing
necessitates
extensive
medical
intervention
at
costly
healthcare
expenses.
Wound
care
management
is
mainly
dependent
on
discovery
new
appropriate
chronic
dressing
materials,
it
remains
focus
research
in
care.
Biocompatible
metallic
nanoparticle-loaded
offers
novel
opportunity
for
effectively
overcoming
inherent
drawbacks
traditional
particularly
nonhealing
wounds
due
to
their
clinical
complexity,
example,
infections,
irritation,
trauma,
persistence
foreign
body
or
bacterial
proteins,
ischemia.
In
this
review,
we
will
primarily
advancements
nanoparticle-based
antibacterial
antioxidant
materials
(e.g.,
hydrogels,
electrospun
scaffolds,
sponges,
films)
treatment
overcome
limitations
dressings.
Skin
cancer
has
emerged
as
the
fifth
most
commonly
reported
in
world,
causing
a
burden
on
global
health
and
economy.
The
enormously
rising
environmental
changes,
industrialization,
genetic
modification
have
further
exacerbated
skin
statistics.
Current
treatment
modalities
such
surgery,
radiotherapy,
conventional
chemotherapy,
targeted
therapy,
immunotherapy
are
facing
several
issues
related
to
cost,
toxicity,
bioavailability
thereby
leading
declined
anti-skin
therapeutic
efficacy
poor
patient
compliance.
In
context
of
overcoming
this
limitation,
nanotechnological
advancements
been
witnessed
so
far.
Among
various
nanomaterials,
nanoparticles
endowed
exorbitant
advantages
by
acting
both
agents
drug
carriers
for
remarkable
cancer.
small
size
large
surface
area
volume
ratio
escalate
tumor
uptake
through
their
leaky
vasculature
resulting
enhanced
efficacy.
context,
present
review
provides
up
date
information
about
different
types
pathology
cancer,
followed
current
associated
drawbacks.
Furthermore,
it
meticulously
discusses
role
numerous
inorganic,
polymer,
lipid-based
therapy
with
subsequent
descriptions
patents
clinical
trials.
Photodiagnosis and Photodynamic Therapy,
Год журнала:
2024,
Номер
45, С. 103959 - 103959
Опубликована: Янв. 21, 2024
Breast
cancer
(BC)
remains
an
enigmatic
fatal
modality
ubiquitously
prevalent
in
different
parts
of
the
world.
Contemporary
medicines
face
severe
challenges
remediating
and
healing
breast
cancer.
Due
to
its
spatial
specificity
nominal
invasive
therapeutic
regime,
photothermal
therapy
(PTT)
has
attracted
much
scientific
attention
down
lane.
PTT
utilizes
a
near-infrared
(NIR)
light
source
irradiate
tumor
target
intravenously
or
non-invasively,
which
is
converted
into
heat
energy
over
optical
fibre.
Dynamic
progress
nanomaterial
synthesis
was
achieved
with
specialized
visual,
physicochemical,
biological,
pharmacological
features
make
up
for
inadequacies
expand
horizon
PTT.
Numerous
nanomaterials
have
substantial
NIR
absorption
can
function
as
efficient
transducers.
It
achievable
limit
wavelength
range
absorbance
peak
specific
by
manipulating
their
synthesis,
enhancing
precision
quality
Along
same
lines,
various
are
conjugated
wide
surface-modifying
chemicals,
including
polymers
antibodies,
may
modify
persistence
diminish
toxicity
concerns.
In
this
article,
we
tend
put
forth
insights
fundamental
conceptualizations
on
pre-existing
advances
upon
conjugation
biocompatible
working
synergy
combat
cancer,
encompassing
several
strategies
like
immunotherapy,
chemotherapy,
photodynamic
therapy,
radiotherapy
coupled
Additionally,
role
mechanisms
nanoparticles,
well
possible
alternatives
PTT,
summarized
distinctive
integral
aspect
article.
