Journal of Agricultural and Food Chemistry,
Год журнала:
2024,
Номер
72(9), С. 4928 - 4938
Опубликована: Фев. 23, 2024
Sliver
nanoparticles
(AgNPs)
have
attracted
tremendous
interest
as
an
alternative
to
commercially
available
antibiotics
due
their
low
microbial
resistance
and
broad-spectrum
antimicrobial
activity.
However,
AgNPs
are
highly
reactive
unstable
susceptible
fast
oxidation.
Synthesizing
stable
efficient
using
green
chemistry
principles
remains
a
major
challenge.
To
address
this
issue,
we
establish
facile
route
form
AgNP-doped
zein
nanoparticle
core–satellite
superstructures
with
ultralow
minimum
bactericidal
concentration
(MBC).
In
brief,
polyphenol
surface-functionalization
of
was
performed,
the
epigallocatechin
gallate
(EGCG)
layer
on
served
reducing-cum-stabilizing
agent.
We
used
EGCG-decorated
(ZE)
template
direct
nucleation
growth
develop
metallized
hybrid
(ZE-Ag).
The
monodispersed
(∼150
nm)
decorated
∼4.9
nm
were
synthesized
successfully.
spatial
restriction
EGCG
by
confined
only
surface
particles,
which
prevented
formation
entangled
clusters
polyphenols
concomitantly
inhibited
coalescence
oxidation
AgNPs.
Thus,
strategy
improved
effective
specific
area
AgNPs,
result,
ZE-Ag
efficiently
killed
indicator
bacteria,
Escherichia
coli
(E.
coli)
Methicillin-resistant
Staphylococcus
aureus(MRSA)
after
20
min
incubation,
MBCs
2
4
μg/mL,
respectively.
This
situation
indicated
that
as-prepared
possessed
potent
short-term
sterilization
capability.
Moreover,
simulated
wound
infection
model
also
confirmed
promising
application
composite.
work
provides
new
insights
into
synthesis
emerging
in
food
preservation,
packaging,
biomedicine,
catalysis.
Molecules,
Год журнала:
2023,
Номер
28(18), С. 6624 - 6624
Опубликована: Сен. 14, 2023
Knowing
the
beneficial
aspects
of
nanomedicine,
scientists
are
trying
to
harness
applications
nanotechnology
in
diagnosis,
treatment,
and
prevention
diseases.
There
also
potential
uses
designing
medical
tools
processes
for
new
generation
scientists.
The
main
objective
conducting
this
research
review
is
gather
widespread
nanomedicine
under
one
heading
highlight
standard
practices
field.
Comprehensive
has
been
conducted
incorporate
latest
data
related
medicine
therapeutics
derived
from
acknowledged
scientific
platforms.
Nanotechnology
used
conduct
sensitive
procedures.
showing
successful
fields
diagnostics,
disease
regenerative
medicine,
gene
therapy,
dentistry,
oncology,
aesthetics
industry,
drug
delivery,
therapeutics.
A
thorough
association
cooperation
between
physicians,
clinicians,
researchers,
technologies
will
bring
forward
a
future
where
there
more
calculated,
outlined,
technically
programed
field
nanomedicine.
Advances
being
made
overcome
challenges
associated
with
application
due
pathophysiological
basis
This
highlights
multipronged
how
proving
health
industry.
need
minimize
health,
environmental,
ethical
concerns
linked
nanotechnology.
Abstract
This
study
marks
a
pioneering
effort
in
utilizing
Vachellia
tortilis
subsp.
raddiana
(Savi)
Kyal.
&
Boatwr.,
(commonly
known
as
acacia
)
leaves
both
reducing
and
stabilizing
agent
the
green
“eco-friendly”
synthesis
of
silver
nanoparticles
(AgNPs).
The
research
aimed
to
optimize
AgNPs
process
by
investigating
influence
pH,
temperature,
extract
volume,
contact
time
on
reaction
rate
resulting
AgNPs'
morphology
well
discuss
potential
detecting
some
heavy
metals.
Various
characterization
methods,
such
UV–vis
spectroscopy,
X-ray
diffraction
(XRD),
scanning
electron
microscopy
(SEM),
infrared
spectroscopy
(IR),
Zeta
sizer,
EDAX,
transmitting
(TEM),
were
used
thoroughly
analyze
properties
synthesized
AgNPs.
XRD
results
verified
successful
production
with
crystallite
size
between
20
30
nm.
SEM
TEM
analyses
revealed
that
are
primarily
spherical
rod-shaped,
sizes
ranging
from
8
41
Significantly,
was
notably
higher
basic
conditions
(pH
10)
at
70
°C.
These
underscore
effectiveness
source
for
sustainable
synthesis.
also
examined
ability
detect
various
metal
ions
colorimetrically,
including
Hg
2+
,
Cu
Pb
Co
.
UV–Vis
proved
useful
this
purpose.
color
shifts
brownish-yellow
pale
yellow,
colorless,
red,
reddish
yellow
when
ions,
respectively.
change
an
alteration
absorbance
band,
vanishing
shifting
423
352
nm,
438
429
nm
showed
high
sensitivity,
detection
limits
1.322
×
10
–5
M,
1.37
–7
1.63
1.34
–4
M
highlights
using
eco-friendly
their
environmental
sensors
metals,
showcasing
strong
capabilities
colorimetric
Frontiers in Pharmacology,
Год журнала:
2024,
Номер
15
Опубликована: Авг. 8, 2024
Silver
nanoparticles
(AgNPs)
have
gained
significant
attention
in
biomedical
applications
due
to
their
unique
physicochemical
properties.
This
review
focuses
on
the
roles
of
AgNPs
antimicrobial
activity,
anticancer
therapy,
and
wound
healing,
highlighting
potential
address
critical
health
challenges.
Frontiers in Microbiology,
Год журнала:
2024,
Номер
15
Опубликована: Июль 31, 2024
Nanoparticles
play
a
crucial
role
in
the
field
of
nanotechnology,
offering
different
properties
due
to
their
surface
area
attributed
small
size.
Among
them,
silver
nanoparticles
(AgNPs)
have
attracted
significant
attention
antimicrobial
properties,
with
applications
that
date
back
from
ancient
medicinal
practices
contemporary
commercial
products
containing
ions
or
nanoparticles.
AgNPs
possess
broad-spectrum
biocidal
potential
against
bacteria,
fungi,
viruses,
and
Mycobacterium,
addition
exhibiting
synergistic
effects
when
combined
certain
antibiotics.
The
mechanisms
underlying
its
action
include
generation
oxygen-reactive
species,
damage
DNA,
rupture
bacterial
cell
membranes
inhibition
protein
synthesis.
Recent
studies
highlighted
effectiveness
various
clinically
relevant
strains
through
combat
antibiotic-resistant
pathogens.
This
review
investigates
proteomic
by
which
exert
effects,
special
focus
on
activity
planktonic
bacteria
biofilms.
Furthermore,
it
discusses
biomedical
non-preparation
antibiotic
formulations,
also
addressing
issue
resistance
RSC Advances,
Год журнала:
2025,
Номер
15(5), С. 3858 - 3903
Опубликована: Янв. 1, 2025
A
sustainable
and
viable
alternative
for
conventional
chemical
physical
approaches
is
the
green
production
of
silver
nanoparticles
(SNPs)
using
plant
extracts.
Biosensors,
Год журнала:
2023,
Номер
13(6), С. 622 - 622
Опубликована: Июнь 5, 2023
Electrochemistry
is
a
genuinely
interdisciplinary
science
that
may
be
used
in
various
physical,
chemical,
and
biological
domains.
Moreover,
using
biosensors
to
quantify
or
biochemical
processes
critical
medical,
biological,
biotechnological
applications.
Nowadays,
there
are
several
electrochemical
for
healthcare
applications,
such
as
the
determination
of
glucose,
lactate,
catecholamines,
nucleic
acid,
uric
so
on.
Enzyme-based
analytical
techniques
rely
on
detecting
co-substrate
or,
more
precisely,
products
catalyzed
reaction.
The
glucose
oxidase
enzyme
generally
enzyme-based
measure
tears,
blood,
etc.
among
all
nanomaterials,
carbon-based
nanomaterials
have
been
utilized
thanks
unique
properties
carbon.
sensitivity
can
up
pM
levels
nanobiosensor,
these
sensors
very
selective,
enzymes
specific
their
substrates.
Furthermore,
frequently
fast
reaction
times,
allowing
real-time
monitoring
analyses.
These
biosensors,
however,
drawbacks.
Changes
temperature,
pH,
other
environmental
factors
influence
stability
activity
enzymes,
affecting
reliability
repeatability
readings.
Additionally,
cost
immobilization
onto
appropriate
transducer
surfaces
might
prohibitively
expensive,
impeding
large-scale
commercialization
widespread
use
biosensors.
This
review
discusses
design,
detection,
nanobiosensors,
recent
applications
studies
evaluated
tabulated.
