Frontiers in Nutrition,
Год журнала:
2022,
Номер
9
Опубликована: Ноя. 17, 2022
Asparagopsis
taxiformis
is
a
significant
source
of
phenolics.
Owing
to
the
incessant
demand
green
extraction
procedures
for
phenolics
from
A.
taxiformis,
ultrasound-assisted
(UAE)
using
deep
eutectic
solvents
(DESs)
was
optimized.
Among
tested
DESs,
betaine-levulinic
acid
afforded
highest
total
phenolic
content
(TPC).
Moreover,
optimal
conditions
elucidated
single-factor
and
response
surface
methodologies
comprised
52.41°C
ultrasonic
temperature,
46.48%
water
DES,
26.99
ml/g
liquid-to-solid
ratio.
The
corresponding
TPC
(56.27
mg
GAE/100
g
DW)
antioxidant
ability
fitted
predicted
values.
UAE
superior
abilities
with
DESs
than
traditional
solvents.
Using
UHPLC-MS,
seven
acids,
18
flavonoids,
two
bromophenols
were
identified
quantified.
DES-UAE
compound
number
(26)
sum
contents.
These
results
disclose
high
efficiency
provide
basis
higher-value
application
this
species.
Fortschritte der Chemie Organischer Naturstoffe/Fortschritte der Chemie organischer Naturstoffe/Progress in the chemistry of organic natural products,
Год журнала:
2023,
Номер
unknown, С. 1 - 546
Marine Drugs,
Год журнала:
2021,
Номер
19(7), С. 358 - 358
Опубликована: Июнь 23, 2021
Macroalgae,
or
seaweeds,
are
a
rich
source
of
components
which
may
exert
beneficial
effects
on
the
mammalian
gut
microbiota
through
enhancement
bacterial
diversity
and
abundance.
An
imbalance
bacteria
has
been
linked
to
development
disorders
such
as
inflammatory
bowel
disease,
immunodeficiency,
hypertension,
type-2-diabetes,
obesity,
cancer.
This
review
outlines
current
knowledge
from
in
vitro
vivo
studies
concerning
potential
therapeutic
application
seaweed-derived
polysaccharides,
polyphenols
peptides
modulate
diet.
Polysaccharides
fucoidan,
laminarin,
alginate,
ulvan
porphyran
unique
seaweeds.
Several
have
shown
their
act
prebiotics
positively
microbiota.
Prebiotics
enhance
populations
often
production
short
chain
fatty
acids,
energy
for
gastrointestinal
epithelial
cells,
provide
protection
against
pathogens,
influence
immunomodulation,
induce
apoptosis
colon
cancer
cells.
The
oral
bioaccessibility
bioavailability
seaweed
is
also
discussed,
including
advantages
limitations
static
dynamic
models
versus
ex
methods.
Seaweed
bioactives
show
use
prevention
and,
some
instances,
treatment
human
disease.
However,
it
necessary
confirm
these
potential,
large-scale
clinical
trials.
Where
possible,
we
cited
information
Microbial Biotechnology,
Год журнала:
2021,
Номер
15(3), С. 773 - 792
Опубликована: Сен. 27, 2021
Poly-
and
perfluorinated
chemicals,
including
alkyl
substances
(PFAS),
are
pervasive
in
today's
society,
with
a
negative
impact
on
human
ecosystem
health
continually
emerging.
These
chemicals
now
subject
to
strict
government
regulations,
leading
costly
environmental
remediation
efforts.
Commercial
polyfluorinated
compounds
have
been
called
'forever
chemicals'
due
their
strong
resistance
biological
chemical
degradation.
Environmental
cleanup
by
bioremediation
is
not
considered
practical
currently.
Implementation
of
will
require
uncovering
understanding
the
rare
microbial
successes
degrading
these
compounds.
This
review
discusses
underlying
reasons
why
degradation
heavily
fluorinated
rare.
Fluorinated
chlorinated
very
different
respect
chemistry
physiology.
Moreover,
end
product
biodegradation,
fluoride,
much
more
toxic
than
chloride.
It
imperative
understand
limitations,
elucidate
physiological
mechanisms
defluorination,
order
better
discover,
study,
engineer
bacteria
that
can
efficiently
degrade
Marine Drugs,
Год журнала:
2021,
Номер
19(5), С. 245 - 245
Опубликована: Апрель 26, 2021
Seaweeds
are
a
potential
source
of
bioactive
compounds
that
useful
for
biotechnological
applications
and
can
be
employed
in
different
industrial
areas
order
to
replace
synthetic
with
components
natural
origin.
Diverse
studies
demonstrate
there
is
solid
ground
the
exploitation
seaweed
prevent
illness
ensure
better
healthier
lifestyle.
Among
algal
molecules,
phenolic
produced
as
secondary
metabolites
beneficial
effects
on
plants,
also
human
beings
animals,
due
their
inherent
properties,
which
exert
antioxidant,
antiviral,
antimicrobial
activities.
The
use
pharmaceutical,
nutraceutical,
cosmetics,
food
industries
may
provide
outcomes
could
enhance
health.
Through
production
healthy
foods
drugs,
from
seaweeds
help
treatment
diseases.
This
review
aims
highlight
importance
seaweeds,
scope
nature
impact
these
have
animal
health
through
nutraceutical
pharmaceutical
products.
Molecules,
Год журнала:
2022,
Номер
27(4), С. 1449 - 1449
Опубликована: Фев. 21, 2022
Since
the
middle
of
last
century,
marine
organisms
have
been
identified
as
producers
chemically
and
biologically
diverse
secondary
metabolites
which
exerted
various
biological
activities
including
anticancer,
anti-inflammatory,
antioxidant,
antimicrobial,
antifouling
others.
This
review
primarily
focuses
on
phenolic
compounds
their
derivatives
with
potent
anticancer
activity,
isolated
and/or
modified
in
decade.
Reports
elucidation
structures
well
biosynthetic
studies
total
synthesis
are
also
covered.
Presented
inhibited
cancer
cells
proliferation
or
migration,
at
sub-micromolar
nanomolar
concentrations
(lamellarins
D
(37),
M
(38),
K
(39),
aspergiolide
B
(41),
fradimycin
(62),
makulavamine
J
(66),
mayamycin
(69),
N-acetyl-N-demethylmayamycin
(70)
norhierridin
(75)).
In
addition,
they
exhibited
properties
by
a
mechanism
induction
apoptosis
inhibition
cell
migration
invasive
potential.
Finally,
phlorotannins
1-7
bromophenols
12-29
represent
most
researched
compounds,
former
recognized
protective
agents
against
UVB
gamma
radiation-induced
skin
damages.
were
assorted
into
six
main
classes:
phlorotannins,
bromophenols,
flavonoids,
coumarins,
terpenophenolics,
quinones
hydroquinones.
The
that
could
not
be
attributed
to
any
above-mentioned
classes
grouped
separate
class
named
miscellaneous
compounds.
Marine Drugs,
Год журнала:
2023,
Номер
21(6), С. 323 - 323
Опубликована: Май 26, 2023
Polyphenols
are
compounds
found
in
various
plants
and
foods,
known
for
their
antioxidant
anti-inflammatory
properties.
Recently,
researchers
have
been
exploring
the
therapeutic
potential
of
marine
polyphenols
other
minor
nutrients
that
algae,
fish
crustaceans.
These
unique
chemical
structures
exhibit
diverse
biological
properties,
including
anti-inflammatory,
antioxidant,
antimicrobial
antitumor
action.
Due
to
these
being
investigated
as
possible
agents
treatment
a
wide
variety
conditions,
such
cardiovascular
disease,
diabetes,
neurodegenerative
diseases
cancer.
This
review
focuses
on
applications
human
health,
also,
phenolic
classes,
extraction
methods,
purification
techniques
future
compounds.
