Bacillus amyloliquefaciens Probiotics Mix Supplementation in a Broiler Leaky Gut Model DOI Creative Commons
Darwin Horyanto, Yadav S. Bajagai, Advait Kayal

и другие.

Microorganisms, Год журнала: 2024, Номер 12(2), С. 419 - 419

Опубликована: Фев. 19, 2024

The supplementation of antimicrobial growth promoters (AGPs) has been banned in many countries because the emergence antimicrobial-resistant pathogens poultry products and environment. Probiotics have broadly studied demonstrated as a promising AGP substitute. Our study is centred on effects multi-strain Bacillus-based probiotic product broiler production performance gut microbial profile dexamethasone-induced leaky challenge. Two hundred fifty-six chicks were hatched randomly assigned into four groups (wheat-soybean meal basal diet (BD) = non-supplemented control (C), BD supplemented with dexamethasone week 4 (CD), containing from day one (P), during challenge (PD)). caecal, gizzard, jejunal lumen mucosa swab microbiota by 16S rRNA gene sequencing. Bacillus significantly improved altered caecal (p ≤ 0.05), but no significant impact was observed other sections.

Язык: Английский

Probiotics: mechanism of action, health benefits and their application in food industries DOI Creative Commons
Anam Latif, Aamir Shehzad, Sobia Niazi

и другие.

Frontiers in Microbiology, Год журнала: 2023, Номер 14

Опубликована: Авг. 17, 2023

Probiotics, like lactic acid bacteria, are non-pathogenic microbes that exert health benefits to the host when administered in adequate quantity. Currently, research is being conducted on molecular events and applications of probiotics. The suggested mechanisms by which probiotics their action include; competitive exclusion pathogens for adhesion sites, improvement intestinal mucosal barrier, gut immunomodulation, neurotransmitter synthesis. This review emphasizes recent advances emerging food industry. Due capability modulate microbiota attenuate immune system, could be used as an adjuvant hypertension, hypercholesterolemia, cancer, gastrointestinal diseases. Considering functional properties, dairy, beverage, baking industries. After developing latest techniques researchers, can now survive within harsh processing conditions withstand GI stresses quite effectively. Thus, potential efficiently utilized a commercial scale

Язык: Английский

Процитировано

204
Anti-Inflammatory and Antioxidative Phytogenic Substances against Secret Killers in Poultry: Current Status and Prospects DOI Creative Commons
Shereen Basiouni, Guillermo Téllez–Isaías, Juan D. Latorre

и другие.

Veterinary Sciences, Год журнала: 2023, Номер 10(1), С. 55 - 55

Опубликована: Янв. 14, 2023

Chronic stress is recognized as a secret killer in poultry. It associated with systemic inflammation due to cytokine release, dysbiosis, and the so-called leaky gut syndrome, which mainly results from oxidative reactions that damage barrier function of cells lining wall. Poultry, especially genetically selected broiler breeds, frequently suffer these chronic symptoms when exposed multiple stressors their growing environments. Since inflammatory damages are multi-stage long-term processes, overshooting immune down-stream effects also negatively affect animal's microbiota, finally impair its performance commercial value. Means counteract poultry other animals are, therefore, highly welcome. Many phytogenic substances, including flavonoids phenolic compounds, known exert anti-inflammatory antioxidant effects. In this review, firstly, main poultry, such heat stress, mycotoxins, dysbiosis diets contain oxidized lipids trigger inflammation, discussed, along key transcription factors involved related signal transduction pathways. Secondly, most promising substances current applications ameliorate highlighted.

Язык: Английский

Процитировано

48
Probiotics and Food Bioactives: Unraveling Their Impact on Gut Microbiome, Inflammation, and Metabolic Health DOI
Alice Njolke Mafe, Great Iruoghene Edo, Patrick Othuke Akpoghelie

и другие.

Probiotics and Antimicrobial Proteins, Год журнала: 2025, Номер unknown

Опубликована: Янв. 14, 2025

Язык: Английский

Процитировано

8
A review on probiotics and dietary bioactives: Insights on metabolic well-being, gut microbiota, and inflammatory responses DOI Creative Commons
Alice Njolke Mafe, Great Iruoghene Edo,

Osamah S. Majeed

и другие.

Food Chemistry Advances, Год журнала: 2025, Номер 6, С. 100919 - 100919

Опубликована: Фев. 11, 2025

Язык: Английский

Процитировано

4
Campylobacter jejuni in Poultry: Pathogenesis and Control Strategies DOI Creative Commons
Walid Ghazi Al Hakeem, Shahna Fathima,

Revathi Shanmugasundaram

и другие.

Microorganisms, Год журнала: 2022, Номер 10(11), С. 2134 - 2134

Опубликована: Окт. 28, 2022

C. jejuni is the leading cause of human foodborne illness associated with poultry, beef, and pork consumption. highly prevalent in commercial poultry farms, where horizontal transmission from environment considered to be primary source jejuni. As an enteric pathogen, expresses virulence factors regulated by a two-component system that mediates jejuni's ability survive host. survives reproduces avian intestinal mucus. The mucus sulfated sialylated compared modulating pathogenicity into near commensal bacteria poultry. Birds are usually infected two four weeks age remain colonized until they reach market age. A small dose (around 35 CFU/mL) sufficient for successful bird colonization. In U.S., chickens raised under antibiotic-free environments, additional strategies required reduce prevalence on broilers farms. Strict biosecurity measures can decrease more than 50% at Vaccination probiotics, prebiotics, synbiotics, organic acids, bacteriophages, bacteriocins, quorum sensing inhibitors supplementation improve gut health competitively exclude load broilers. Most mentioned showed promising results; however, not fully implemented production. Current knowledge morphology, transmission, pathogenesis available preharvest colonization addressed this review.

Язык: Английский

Процитировано

43
Effect of Bacillus Probiotics on the Immunological Responses of Nile Tilapia (Oreochromis niloticus): A Review DOI Creative Commons

Vicent Michael Shija,

Kwaku Amoah, Jia Cai

и другие.

Fishes, Год журнала: 2023, Номер 8(7), С. 366 - 366

Опубликована: Июль 13, 2023

The use of antibiotics and therapeutics for Nile tilapia has increased along with its production intensification. Probiotics have been studied as an alternative to the excessive in fish diets. Studies demonstrated that dietary Bacillus probiotic inclusion promotes faster growth disease resistance farmed species. Despite advances research, there is still uncertainty about mechanisms controlling immune response fish. In this review, we summarize discuss recent research on responses probiotics. Through immunological information including phagocytosis, lysozyme activity, respiratory antioxidant proteins, complement immune-related gene expression, researchers hope develop effective strategies successfully using probiotics Oreochromis niloticus farming.

Язык: Английский

Процитировано

33
Immunomodulatory Effects of Natural Feed Additives for Meat Chickens DOI Creative Commons
Clive J. C. Phillips, Babak Hosseintabar‐Ghasemabad, И.Ф. Горлов

и другие.

Life, Год журнала: 2023, Номер 13(6), С. 1287 - 1287

Опубликована: Май 30, 2023

Broiler chickens are increasingly kept in large numbers intensive housing conditions that stressful, potentially depleting the immune system. With prohibition of use antibiotics poultry feed spreading worldwide, it is necessary to consider role natural additives and antibiotic alternatives stimulate chickens' systems. We review literature describe phytogenic have immunomodulatory benefits broilers. initially major active ingredients from plants, particularly flavonoids, resveratrol humic acid, then herbs, spices, other plants their byproducts effects. The research reviewed demonstrates effectiveness many improving avian system therefore broiler health. However, some, perhaps all, potential reduce immunocompetence if given excessive amounts. Sometimes more effective when combination. There an urgent need determine tolerance levels optimum doses for deemed most suitable replace diet chickens. Effective replacement likely with readily available additives, such as olive oil byproducts, leaves alfalfa. It concluded function plant-derived will be possible, but further doses.

Язык: Английский

Процитировано

26
Recent progress on engineered micro/nanomaterials mediated modulation of gut microbiota for treating inflammatory bowel disease DOI

Lingling Kan,

Ziwen Zheng,

Wanyue Fu

и другие.

Journal of Controlled Release, Год журнала: 2024, Номер 370, С. 43 - 65

Опубликована: Апрель 17, 2024

Язык: Английский

Процитировано

14
Chitosan and its derivatives: A novel approach to gut microbiota modulation and immune system enhancement DOI
Great Iruoghene Edo, Alice Njolke Mafe,

Ali B. M. Ali

и другие.

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 289, С. 138633 - 138633

Опубликована: Дек. 13, 2024

Язык: Английский

Процитировано

9
Effect of Saccharomyces cerevisiae Postbiotics and Essential Oil on Growth Performance and Intestinal Health of Weanling Pigs During K88 ETEC Infection DOI
Hui Yan,

Qian Xing,

Xiarui Xiao

и другие.

Journal of Animal Science, Год журнала: 2024, Номер 102

Опубликована: Янв. 1, 2024

Abstract Enterotoxigenic Escherichia coli (ETEC) is one of the major bacterial infections, causing substantial economic losses globally in swine industry. This study aimed to investigate impact low Saccharomyces cerevisiae fermentation postbiotics (SCFP), high SCFP, essential oil (EO), or their combination on growth performance and health weanling pigs during ETEC infection. Forty-eight male were randomly allocated five groups: 1) control group (CON—basal diet, n = 16); 2) SCFP (LSC—basal diet + 1.25 g/kg 8); 3) (HSC—basal 2 4) (EO—basal 0.4 EO, 5) EO (SE—basal 8). On day 15 trial, CON divided into positive (PC) negative (NC), all pigs, except NC, challenged with ETEC. Under normal condition, dietary LSC, HSC, increased average daily gain (ADG) (P < 0.05), decreased F:G ratio 0.05) accompanied by malondialdehyde (MDA) increases catalase (CAT), total superoxide dismutase (T-SOD), antioxidant capacity (T-AOC) indicating enhanced anti-oxidative capacity, as well IL-2, IL-8, INF-γ, mitigated systemic inflammation. During infection, treatments alleviated ETEC-induced ADG reduction, diarrhea, damages intestinal permeability morphology, down-regulation tight junctions (Claudin1, ZO-1, Occludin), while HSC exhibited additional protections. All CAT, T-SOD, T-AOC, MDA serum jejunal mucosa at similar degrees 0.05). Moreover, inflammation shown IL-6, TNF-α, IL-4 IL-10 immunity IgG mucosal sIgA SE further reduced INF-γ TNF-α than LSC aligning protection against diarrhea Additionally, key gut bacteria (e.g., Terrisporobacter) related benefits identified. In sum, protected damage through regulation redox immune homeostasis. HSP offered extra disease for Our provided new insight use feed additives context animal states.

Язык: Английский

Процитировано

8