Critical Reviews in Food Science and Nutrition,
Год журнала:
2022,
Номер
64(1), С. 87 - 109
Опубликована: Авг. 2, 2022
Epigallocatechin
gallate
(EGCG)
is
one
of
the
most
abundant
and
powerful
flavonoids
contained
in
green
tea.
Because
global
increase
tea
consumption,
there
has
been
a
general
interest
understanding
its
health
benefits,
including
bioactive
compounds
like
EGCG.
Indeed,
preclinical
evidence
already
indicates
that
EGCG
demonstrated
strong
antioxidant
anti-inflammatory
properties
could
be
essential
protecting
against
metabolic
syndrome.
The
current
review
explores
clinical
reporting
on
beneficial
effects
supplementation
obese
subjects
or
patients
with
diverse
complications
include
type
2
diabetes
cardiovascular
disease.
discussion
incorporates
impact
different
formulations
EGCG,
as
well
effective
doses
treatment
duration.
Importantly,
besides
highlighting
potential
use
nutraceutical,
also
discusses
crucial
related
to
pharmaceutical
development
an
agent
hinder
diseases,
bioavailability
metabolism
profile,
well-known
biological
properties.
Nutrients,
Год журнала:
2023,
Номер
15(12), С. 2749 - 2749
Опубликована: Июнь 14, 2023
The
Western
diet
is
a
modern
dietary
pattern
characterized
by
high
intakes
of
pre-packaged
foods,
refined
grains,
red
meat,
processed
high-sugar
drinks,
candy,
sweets,
fried
conventionally
raised
animal
products,
high-fat
dairy
and
high-fructose
products.
present
review
aims
to
describe
the
effect
on
metabolism,
inflammation,
antioxidant
status;
impact
gut
microbiota
mitochondrial
fitness;
cardiovascular
health,
mental
cancer;
sanitary
cost
diet.
To
achieve
this
goal,
consensus
critical
was
conducted
using
primary
sources,
such
as
scientific
articles,
secondary
including
bibliographic
indexes,
databases,
web
pages.
Scopus,
Embase,
Science
Direct,
Sports
Discuss,
ResearchGate,
Web
were
used
complete
assignment.
MeSH-compliant
keywords
“Western
diet”,
“inflammation”,
“metabolic
health”,
fitness”,
“heart
disease”,
“cancer”,
“oxidative
stress”,
“mental
“metabolism”
used.
following
exclusion
criteria
applied:
(i)
studies
with
inappropriate
or
irrelevant
topics,
not
germane
review’s
focus;
(ii)
Ph.D.
dissertations,
proceedings
conferences,
unpublished
studies.
This
information
will
allow
for
better
comprehension
nutritional
behavior
its
an
individual’s
metabolism
well
national
systems.
Finally,
practical
applications
derived
from
are
made.
Current Issues in Molecular Biology,
Год журнала:
2023,
Номер
45(8), С. 6651 - 6666
Опубликована: Авг. 12, 2023
Oxidative
stress
is
a
critical
factor
in
the
pathogenesis
and
progression
of
diabetes
its
associated
complications.
The
imbalance
between
reactive
oxygen
species
(ROS)
production
body’s
antioxidant
defence
mechanisms
leads
to
cellular
damage
dysfunction.
In
diabetes,
chronic
hyperglycaemia
mitochondrial
dysfunction
contribute
increased
ROS
production,
further
exacerbating
oxidative
stress.
This
burden
adversely
affects
various
aspects
including
impaired
beta-cell
function
insulin
resistance,
leading
disrupted
glucose
regulation.
Additionally,
stress-induced
blood
vessels
endothelial
development
diabetic
vascular
complications
such
as
retinopathy,
nephropathy,
cardiovascular
diseases.
Moreover,
organs
tissues
throughout
body,
kidneys,
nerves,
eyes,
are
vulnerable
stress,
resulting
neuropathy,
retinopathy.
Strategies
mitigate
include
therapy,
lifestyle
modifications,
effective
management
hyperglycaemia.
However,
research
necessary
comprehensively
understand
underlying
evaluate
efficacy
interventions
preventing
treating
By
addressing
it
might
be
possible
alleviate
improve
patient
outcomes.
Nutrients,
Год журнала:
2021,
Номер
13(6), С. 1951 - 1951
Опубликована: Июнь 6, 2021
It
has
been
established,
worldwide,
that
non-communicable
diseases
such
as
obesity,
diabetes,
metabolic
syndrome,
and
cardiovascular
events
account
for
a
high
percentage
of
morbidity
mortality
in
contemporary
societies.
Several
modifiable
risk
factors,
sedentary
activities,
sleep
deprivation,
smoking,
unhealthy
dietary
habits
have
contributed
to
this
increase.
Healthy
nutrition
terms
adherence
the
Mediterranean
diet
(MD),
rich
fruits,
legumes,
vegetables,
olive
oil,
herbs,
spices,
fiber
intake
may
contribute
decrease
pandemic.
The
beneficial
effects
MD
can
be
mainly
attributed
its
numerous
components
anti-inflammatory
antioxidant
properties.
Moreover,
further
improvement
reproductive
health,
modify
neurodegenerative
diseases,
protect
against
depression
psychosocial
maladjustment.
There
is
also
evidence
highlighting
impact
healthy
female
people
on
composition
gut
microbiota
future
overall
health
their
offspring.
therefore
important
highlight
metabolic,
reproductive,
mental
while
shaping
generations.
enhanced
by
increased
physical
activity
context
well-balanced
lifestyle.
Plants,
Год журнала:
2023,
Номер
12(6), С. 1217 - 1217
Опубликована: Март 7, 2023
Polyphenol
has
been
used
in
treatment
for
some
health
disorders
due
to
their
diverse
promoting
properties.
These
compounds
can
reduce
the
impacts
of
oxidation
on
human
body,
prevent
organs
and
cell
structure
against
deterioration
protect
functional
integrity.
The
abilities
are
attributed
high
bioactivity
imparting
them
antioxidative,
antihypertensive,
immunomodulatory,
antimicrobial,
antiviral
activity,
as
well
anticancer
application
polyphenols
such
flavonoids,
catechin,
tannins,
phenolic
acids
food
industry
bio-preservative
substances
foods
beverages
exert
a
superb
activity
inhibition
oxidative
stress
via
different
types
mechanisms.
In
this
review,
detailed
classification
polyphenolic
compunds
important
with
special
focus
addressed.
Additionally,
ability
inhibit
SARS-CoV-2
could
be
alternative
therapy
treat
COVID
patients.
Inclusions
various
have
demonstrated
extend
shelf
life
they
positive
(antioxidative,
anticancer).
virus
reported.
Considering
natural
occurrence
GRAS
status
highly
recommended
food.
Molecules,
Год журнала:
2022,
Номер
27(19), С. 6280 - 6280
Опубликована: Сен. 23, 2022
Polyphenols
(PPs)
are
a
large
group
of
phytochemicals
containing
phenolic
rings
with
two
or
more
hydroxyl
groups.
They
possess
powerful
antioxidant
properties,
multiple
therapeutic
effects,
and
possible
health
benefits
in
vivo
vitro,
as
well
reported
clinical
studies.
Considering
their
free-radical
scavenging
anti-inflammatory
these
substances
can
be
used
to
treat
different
kinds
conditions
associated
metabolic
disorders.
Many
symptoms
syndrome
(MtS),
including
obesity,
dyslipidemia,
atherosclerosis,
elevated
blood
sugar,
accelerating
aging,
liver
intoxication,
hypertension,
cancer
neurodegenerative
disorders,
substantially
relieved
by
dietary
PPs.
The
present
study
explores
the
bioprotective
properties
underlying
mechanisms
A
detailed
understanding
natural
compounds
will
open
up
new
opportunities
for
producing
unique
PP-rich
medicinal
plans,
ultimately
affirming
benefits.
Antioxidants,
Год журнала:
2023,
Номер
12(4), С. 860 - 860
Опубликована: Апрель 2, 2023
It
is
more
effective
to
maintain
good
health
than
regain
it
after
losing
it.
This
work
focuses
on
the
biochemical
defense
mechanisms
against
free
radicals
and
their
role
in
building
maintaining
antioxidant
shields,
aiming
show
how
balance,
as
much
possible,
situations
which
we
are
exposed
radicals.
To
achieve
this
aim,
foods,
fruits,
marine
algae
with
a
high
content
should
constitute
basis
of
nutritional
elements,
since
natural
products
known
have
significantly
greater
assimilation
efficiency.
review
also
gives
perspective
use
antioxidants
can
extend
life
food
products,
by
protecting
them
from
damage
caused
oxidation
well
additives.
Life
expectancy
has
been
on
the
rise
for
past
few
decades,
but
healthy
life
not
kept
pace,
leading
to
a
global
burden
of
age-associated
disorders.
Advancing
age
is
accompanied
by
chronic
increase
in
basal
systemic
inflammation,
termed
inflammaging,
contributing
towards
an
increased
risk
developing
diseases
old
age.
This
article
reviews
recent
literature
formulate
hypotheses
regarding
how
inflammaging
plays
crucial
role
driving
and
ill
health
older
adults.
Here,
we
discuss
non-pharmacological
intervention
strategies
(diet,
nutraceutical
supplements,
phytochemicals,
physical
activity,
microbiome-based
therapies)
targeting
restore
We
also
consider
alternative
existing
pharmacological
interventions
(Caloric
restriction
mimetics,
p38
mitogen-activated
protein
kinase
inhibitors)
explore
novel
targets
(senolytics)
aimed
at
combating
optimising
ageing
process
lifespan.
Deleted Journal,
Год журнала:
2023,
Номер
13(2), С. 529 - 540
Опубликована: Апрель 14, 2023
The
Mediterranean
diet
has
long
been
recognized
as
one
of
the
most
effective
ways
to
prevent
and
improve
cardiovascular
disease.
Extra
virgin
olive
oil
(EVOO)
is
typical
sources
fat
in
which
have
shown
noteworthy
nutritional
value
positive
impact
on
human
health.
It
worth
noting
that
EVOO
owes
its
superior
bioactive
composition.
main
component
monounsaturated
fatty
acids
(MUFAs)
form
oleic
acid.
Oleic
acid
accounts
for
up
70%-80%
EVOO.
Secondly,
contains
approximately
more
than
30
phenolic
compounds,
HT
essential
protection
against
CVDs.
In
this
review,
we
focused
potential
mechanisms
polyphenols
combat
diseases
risk
terms
oxidative
stress,
inflammation,
blood
pressure,
endothelial
function
cholesterol.
This
review
might
provide
a
reference
studies
protective
effects
