Polymers,
Год журнала:
2023,
Номер
15(8), С. 1902 - 1902
Опубликована: Апрель 15, 2023
The
number
of
cancer
patients
is
rapidly
increasing
worldwide.
Among
the
leading
causes
human
death,
can
be
regarded
as
one
major
threats
to
humans.
Although
many
new
treatment
procedures
such
chemotherapy,
radiotherapy,
and
surgical
methods
are
nowadays
being
developed
used
for
testing
purposes,
results
show
limited
efficiency
high
toxicity,
even
if
they
have
potential
damage
cells
in
process.
In
contrast,
magnetic
hyperthermia
a
field
that
originated
from
use
nanomaterials,
which,
due
their
properties
other
characteristics,
clinical
trials
solutions
treatment.
Magnetic
nanomaterials
increase
temperature
nanoparticles
located
tumor
tissue
by
applying
an
alternating
field.
A
very
simple,
inexpensive,
environmentally
friendly
method
fabrication
various
types
functional
nanostructures
adding
additives
spinning
solution
electrospinning
process,
which
overcome
limitations
this
challenging
Here,
we
review
recently
electrospun
nanofiber
mats
support
therapy,
targeted
drug
delivery,
diagnostic
therapeutic
tools,
techniques
ACS Applied Materials & Interfaces,
Год журнала:
2022,
Номер
14(29), С. 33555 - 33566
Опубликована: Июль 18, 2022
Functional
colloidal
nanoparticles
capable
of
converting
between
various
energy
types
are
finding
an
increasing
number
applications.
One
the
relevant
examples
concerns
light-to-heat-converting
that
may
be
useful
for
localized
photothermal
therapy
cancers.
Unfortunately,
quantitative
comparison
and
ranking
nanoheaters
not
straightforward
as
materials
different
compositions
structures
have
photophysical
chemical
properties
interact
differently
with
biological
environment.
In
terms
properties,
most
information
to
rank
these
is
light-to-heat
conversion
efficiency,
which,
along
on
absorption
capacity
material,
can
used
directly
compare
materials.
this
work,
we
evaluate
17
belonging
groups
(plasmonic,
semiconductor,
lanthanide-doped
nanocrystals,
carbon
metal
oxides).
We
conclude
efficiency
alone
meaningful
enough
many
similar
efficiencies─in
range
80-99%─while
they
significantly
differ
in
their
extinction
coefficient.
therefore
constructed
qualitative
based
external
which
takes
into
account
conventionally
defined
its
capacity.
This
demonstrated
differences
samples
more
meaningfully.
Among
studied
systems,
top-ranking
were
black
porous
silicon
CuS
nanocrystals.
These
results
allow
us
select
favorable
photo-based
theranostics
set
a
new
standard
characterization
nanoheaters.
Materials Advances,
Год журнала:
2022,
Номер
3(20), С. 7425 - 7444
Опубликована: Янв. 1, 2022
Magnetic
nanoparticles
(MNPs)
show
tremendous
possibilities
in
the
field
of
biomedicine,
especially
as
therapeutic
agents
for
use
over
a
prolonged
duration.
Nanomaterials,
Год журнала:
2023,
Номер
13(8), С. 1342 - 1342
Опубликована: Апрель 12, 2023
The
design
of
core-shell
nanocomposites
composed
an
iron
oxide
core
and
a
silica
shell
offers
promising
applications
in
the
nanomedicine
field,
especially
for
developing
efficient
theranostic
systems
which
may
be
useful
cancer
treatments.
This
review
article
addresses
different
ways
to
build
oxide@silica
nanoparticles
it
reviews
their
properties
developments
hyperthermia
therapies
(magnetically
or
light-induced),
combined
with
drug
delivery
MRI
imaging.
It
also
highlights
various
challenges
encountered,
such
as
issues
associated
vivo
injection
terms
NP–cell
interactions
control
heat
dissipation
from
NP
external
environment
at
macro
nanoscale.
Arabian Journal of Chemistry,
Год журнала:
2023,
Номер
16(4), С. 104583 - 104583
Опубликована: Янв. 16, 2023
Resistance
to
antimicrobial
drugs
is
an
impending
healthcare
problem
of
growing
significance.
In
the
post-antibiotic
era,
there
a
huge
push
develop
new
tools
for
effectively
treating
bacterial
infections.
Photodynamic
therapy
involves
use
photosensitizer
that
activated
by
light
appropriate
wavelength
in
presence
oxygen.
This
results
generation
singlet
oxygen
molecules
can
kill
target
cells,
including
cancerous
cells
and
microbial
cells.
shown
be
effective
against
parasites,
viruses,
algae,
bacteria.
To
achieve
high
activity,
sufficient
concentration
should
enter
Generally,
photosensitizers
tend
aggregate
aqueous
environments
resulting
weakening
photochemical
activity
lowering
their
uptake
into
Nanocarrier
systems
are
efficient
targeting
improve
therapeutic
efficiency
enhancing
internalization
review
aims
highlight
basic
principles
photodynamic
with
special
emphasis
on
nanosystems
delivering
improving
therapy.
Materials Horizons,
Год журнала:
2023,
Номер
10(11), С. 4757 - 4775
Опубликована: Янв. 1, 2023
Magnetic
nanoparticles
offer
versatile
opportunities
for
anti-cancer
therapy,
stemming
from
a
single
metal
element,
iron,
naturally
processed
by
the
human
body.
Applications
range
magnetic
hyperthermia
to
emerging
fields
of
photothermal
therapy
and
ferroptosis
induction.
Coordination Chemistry Reviews,
Год журнала:
2024,
Номер
507, С. 215751 - 215751
Опубликована: Март 2, 2024
Upon
photo-stimulation,
some
materials
such
as
semiconductors
can
result
in
the
generation
of
heat
through
photothermal
effect.
The
generated
be
used
nanomedicine
for
example
cancer
therapy.
response
to
photostimulation
and
resulting
photothermia
modulated
addition
defects
case
semiconductors,
at
heart
this
review.
Based
on
observation
that
nanoheat
is
catalysis
biomedical
photothermia,
we
present
here
a
summary
recent
works
both
disciplines
explore
nanoengineering
local
atomic
defects,
most
reported
ones,
modulate
activity.
We
highlight
different
synthesis
methods
processes
creating
from
disciplines,
their
physicochemical
physical
fingerprints
elucidating
presence,
impact
properties
activity
nanomaterials.
In
general,
appear
act
like
traps
photogenerated
electrons
after
increasing
recombination
time,
leading
non-radiative
more
efficient
photothermia.
also
show
an
unpredictable
optimal
concertation
obtaining
high
heating
performances.
Moreover,
taking
into
account
great
achievements
field
catalysis,
translated
them
highlighted
future
perspectives
field,
scales
better
understanding
relationship
between
deficient
structure-properties-function
heating.
believe
review,
independently
discipline,
help
elucidate
aspects
activity,
inspire
engineering
new
defect-based
well
detection
methods,
bring
connections
communities
thermal
nanomedicine.
Journal of Functional Biomaterials,
Год журнала:
2024,
Номер
15(8), С. 207 - 207
Опубликована: Июль 25, 2024
Photothermal
therapy
(PTT)
can
overcome
cancer
treatment
resistance
by
enhancing
the
cell
membrane
permeability,
facilitating
drug
accumulation,
and
promoting
release
within
tumor
tissue.
Iron
oxide
nanoparticles
(IONPs)
have
emerged
as
effective
agents
for
PTT
due
to
their
unique
properties
biocompatibility.
Approved
of
anemia,
MRI
contrast
agents,
magnetic
hyperthermia
mediators,
IONPs
also
offer
excellent
light-to-heat
conversion
be
manipulated
using
external
fields
targeted
accumulation
in
specific
Optimizing
parameters
such
laser
wavelength,
power
density,
shape,
size,
iron
oxidation
state,
functionalization,
concentration
is
crucial
IONPs'
effectiveness.
In
addition
PTT,
enhance
other
modalities.
They
improve
oxygenation,
efficacy
radiotherapy
photodynamic
therapy.
trigger
ferroptosis,
a
programmed
death
pathway
mediated
iron-dependent
lipid
peroxidation.
Their
magneto-mechanical
effect
allows
them
exert
mechanical
force
on
cells
destroy
tumors,
minimizing
damage
healthy
This
review
outlines
strategies
management
photothermal
performance
efficiency
with
nanoparticles,
well
synergies
therapies.