Obesity, cancer risk, and time-restricted eating DOI Creative Commons
Manasi Das, Nicholas J. G. Webster

Cancer and Metastasis Reviews, Год журнала: 2022, Номер 41(3), С. 697 - 717

Опубликована: Авг. 19, 2022

Obesity and the associated metabolic syndrome is considered a pandemic whose prevalence steadily increasing in many countries worldwide. It complex, dynamic, multifactorial disorder that presages development of several metabolic, cardiovascular, neurodegenerative diseases, increases risk cancer. In patients with newly diagnosed cancer, obesity worsens prognosis, recurrence decreasing survival. The multiple negative effects on cancer outcomes are substantial, great clinical importance. Strategies for weight control have potential utility both prevention efforts enhancing outcomes. Presently, time-restricted eating (TRE) popular dietary intervention involves limiting consumption calories to specific window time without any proscribed caloric restriction or alteration composition. As such, TRE sustainable long-term behavioral modification, when compared other interventions, has shown health benefits animals humans. preliminary data regarding feeding growth animal models promising but studies humans lacking. Interestingly, short-term randomized trials favorable reduce factors; however, yet investigate reductions incidence general population. Few been conducted populations, number underway examine effect biology recurrence. Given simplicity, feasibility, improvements elicited by obese men women, may be useful survivors; implementation setting will require greater in-depth investigation.

Язык: Английский

Time-Restricted Eating and Its Metabolic Benefits DOI Creative Commons

Sneha Mishra,

Patress Persons,

Andrea M. Lorenzo

и другие.

Journal of Clinical Medicine, Год журнала: 2023, Номер 12(22), С. 7007 - 7007

Опубликована: Ноя. 9, 2023

Newer management strategies are being evaluated to treat obesity, which continues increase worldwide. After 12 h of fasting, the body switches from glucose fat metabolism, regulating protein synthesis and autophagy. These cellular responses central metabolic benefits time-restricted eating (TRE), independent calorie restriction weight loss, they have heightened interest in TRE regimens. Controversy remains, however, regarding We reviewed current literature concluded that is equivalent for loss has positive effects patients with diseases such as nonalcoholic fatty liver disease, cancer, cardiovascular disease.

Язык: Английский

Процитировано

15
Metabolic impact of intermittent energy restriction and periodic fasting in patients with type 2 diabetes: a systematic review DOI Creative Commons
Elske L. van den Burg, Petra G. van Peet, Marjolein P. Schoonakker

и другие.

Nutrition Reviews, Год журнала: 2023, Номер 81(10), С. 1329 - 1350

Опубликована: Фев. 4, 2023

Abstract Context The effectiveness of intermittent energy restriction (IER) and periodic fasting (PF) in the management type 2 diabetes (T2D) remains a subject discussion. Objective aim this systematic review is to summarize current knowledge effects IER PF patients with T2D on markers metabolic control need for glucose-lowering medication. Data Sources PubMed, Embase, Emcare, Web Science, Cochrane Library, CENTRAL, Academic Search Premier, Science Direct, Google Scholar, Wiley Online LWW Health Library were searched eligible articles March 20, 2018 (last update performed November 11, 2022). Studies that evaluated or diets adult included. Extraction This reported according PRISMA guidelines. Risk bias was assessed through risk tool. search identified 692 unique records. Thirteen original studies Analysis A qualitative synthesis results constructed because differed widely terms dietary interventions, study design, duration. Glycated hemoglobin (HbA1c) declined response 5 10 studies, glucose 7 studies. In 4 dosage medication could be reduced during PF. Two long-term (≥1 year after ending intervention). benefits HbA1c generally not sustained over long term. There are limited number interventions T2D. Most judged have at least some bias. Conclusion suggest can improve regulation T2D, short Moreover, these may allow reduction Systematic Review Registration PROSPERO registration no. CRD42018104627.

Язык: Английский

Процитировано

14
Time-Restricted Eating Improves Quality of Life Measures in Overweight Humans DOI Open Access

Ainslee Crose,

Alison Alvear,

Stephanie Singroy

и другие.

Nutrients, Год журнала: 2021, Номер 13(5), С. 1430 - 1430

Опубликована: Апрель 23, 2021

Time-restricted eating (TRE) reduces weight in humans, but its effects on quality of life have not been well characterized. By performing a secondary analysis randomized clinical trial, we examined the TRE (12-week intervention, 8 h window) vs. non-TRE (unrestricted eating) (QoL) measures. Twenty subjects with overweight and prolonged window (mean (SD): 15.4 (0.9)) were to either 12 weeks (8 window: (n = 11)) or 9). QoL data collected 36-item Short Form Survey (SF-36) pre- post-intervention. Given two-way ANOVA model post-hoc t-test analysis, group improved limitations due emotional health post-intervention: +97.0 (10.0)) baseline: +66.7 (42.2) (p 0.02) perceived change over last year end intervention: +68.2 (16.2) +52.3 (23.6) 0.001) relative baseline. The TRE: (10.0) non-TRE: +55.6 (44.1) 0.05) (TRE: +44.4 (31.6) 0.04) at post-intervention < 0.025). In conclusion, does adversely affect may be associated modest improvements baseline unrestricted eating; these findings support future studies examining compliance durability.

Язык: Английский

Процитировано

28
Assessing temporal eating pattern in free living humans through the myCircadianClock app DOI
Emily N. C. Manoogian, Julie Wei-Shatzel, Satchidananda Panda

и другие.

International Journal of Obesity, Год журнала: 2022, Номер 46(4), С. 696 - 706

Опубликована: Янв. 8, 2022

Язык: Английский

Процитировано

21
Obesity, cancer risk, and time-restricted eating DOI Creative Commons
Manasi Das, Nicholas J. G. Webster

Cancer and Metastasis Reviews, Год журнала: 2022, Номер 41(3), С. 697 - 717

Опубликована: Авг. 19, 2022

Obesity and the associated metabolic syndrome is considered a pandemic whose prevalence steadily increasing in many countries worldwide. It complex, dynamic, multifactorial disorder that presages development of several metabolic, cardiovascular, neurodegenerative diseases, increases risk cancer. In patients with newly diagnosed cancer, obesity worsens prognosis, recurrence decreasing survival. The multiple negative effects on cancer outcomes are substantial, great clinical importance. Strategies for weight control have potential utility both prevention efforts enhancing outcomes. Presently, time-restricted eating (TRE) popular dietary intervention involves limiting consumption calories to specific window time without any proscribed caloric restriction or alteration composition. As such, TRE sustainable long-term behavioral modification, when compared other interventions, has shown health benefits animals humans. preliminary data regarding feeding growth animal models promising but studies humans lacking. Interestingly, short-term randomized trials favorable reduce factors; however, yet investigate reductions incidence general population. Few been conducted populations, number underway examine effect biology recurrence. Given simplicity, feasibility, improvements elicited by obese men women, may be useful survivors; implementation setting will require greater in-depth investigation.

Язык: Английский

Процитировано

21