Prevalence and Amounts of Common Ingredients Found in Energy Drinks and Shots DOI Open Access
Andrew R. Jagim, Patrick S. Harty, Abdelrahman Barakat

и другие.

Nutrients, Год журнала: 2022, Номер 14(2), С. 314 - 314

Опубликована: Янв. 13, 2022

Energy drinks are one of the most popular packaged beverage products consumed within United States (US). considered a functional beverage, category that also includes sports and nutraceutical beverages.The focus current study was to examine nutrition fact panels top selling commercially available energy drink shot US characterize common ingredient profiles help establish standard definition profile shots for consumers, health care practitioners, researchers.The 75 were identified compiled from multiple commercial retail websites as September 2021. For purpose this study, an must have met following criteria: (A) marketed drink; (B) purported improve energy, focus, or alertness; (C) not sold dietary supplement (no panels); (D) manufactured pre-packaged ready-to-drink beverage; (E) contains at least three (1) caffeine, (2) B-vitamins, (3) sugar, (4) taurine, (5) creatine, (6) quercetin, (7) guarana, (8) ginseng, (9) coenzyme Q10, (10) branched chain amino acids. similar criteria be included: shot; supplement; with small volume (<3.5 mL); ingredients stated above.Twenty fifty-five included in analysis. The number per product (mean ± SD) 18.2 5.7, 15 containing proprietary blends undisclosed amounts. relative prevalence average amounts follows: caffeine (100%; 174.4 81.1 mg), vitamin B6 (72%; 366.9 648.1 percent daily value (%DV)), B3 (67%; 121.44 69.9% DV), B12 5244.5 10,474.6% B5 (37.3%; 113.6 76.6% taurine undisclosed).Our findings suggest high B-vitamins these products, many formulations well above recommended B-vitamins.

Язык: Английский

Role of the gut microbiota in anticancer therapy: from molecular mechanisms to clinical applications DOI Creative Commons
Lin-Yong Zhao,

Jia-Xin Mei,

Gang Yu

и другие.

Signal Transduction and Targeted Therapy, Год журнала: 2023, Номер 8(1)

Опубликована: Май 13, 2023

Abstract In the past period, due to rapid development of next-generation sequencing technology, accumulating evidence has clarified complex role human microbiota in cancer and therapeutic response. More importantly, available seems indicate that modulating composition gut improve efficacy anti-cancer drugs may be feasible. However, intricate complexities exist, a deep comprehensive understanding how interacts with is critical realize its full potential treatment. The purpose this review summarize initial clues on molecular mechanisms regarding mutual effects between development, highlight relationship microbes immunotherapy, chemotherapy, radiation therapy surgery, which provide insights into formulation individualized strategies for management. addition, current emerging microbial interventions as well their clinical applications are summarized. Although many challenges remain now, great importance cannot overstated strategies, it necessary explore holistic approach incorporates modulation cancer.

Язык: Английский

Процитировано

150

The relationship between nutrition and the immune system DOI Creative Commons
Camelia Munteanu, Betty Schwartz

Frontiers in Nutrition, Год журнала: 2022, Номер 9

Опубликована: Дек. 8, 2022

Nutrition plays an essential role in the regulation of optimal immunological response, by providing adequate nutrients sufficient concentrations to immune cells. There are a large number micronutrients, such as minerals, and vitamins, well some macronutrients amino acids, cholesterol fatty acids demonstrated exert very important specific impact on appropriate activity. This review aims summarize at extent amount data accrued date related modulation function certain micro emphasize their importance maintaining human health. Thus, among many, relevant case point examples brought discussed: (1) The vitamin A/all-trans-retinoic-acids (ATRA) acute promyelocytic leukemia, being this utilized efficient therapeutic agent via effective (2) involvement C fight against tumor cells increase active NK (3) stimulation apoptosis, suppression cancer cell proliferation, delayed development mediated calcitriol/vitamin D means immunity (4) use selenium cofactor reach more response COVID vaccination (5). crucial regulate function, which is be sensitive variations macronutrient concentration. Other reviewed well.

Язык: Английский

Процитировано

112

Intermediate role of gut microbiota in vitamin B nutrition and its influences on human health DOI Creative Commons
Zhijie Wan,

Jianheng Zheng,

Zhigang Zhu

и другие.

Frontiers in Nutrition, Год журнала: 2022, Номер 9

Опубликована: Дек. 13, 2022

Vitamin B consists of a group water-soluble micronutrients that are mainly derived from the daily diet. They serve as cofactors, mediating multiple metabolic pathways in humans. As an integrated part human health, gut microbiota could produce, consume, and even compete for vitamin with host. The interplay between host might be crucial factor affecting absorbing processes B. On other hand, supplementation or deficiency impact growth specific bacteria, resulting changes composition function microbiota. Together, systemically contribute to health. In this review, we summarized interactions tried reveal underlying mechanism so can have better understanding its role

Язык: Английский

Процитировано

95

B Vitamins and Their Roles in Gut Health DOI Creative Commons
Khandkar Shaharina Hossain, Sathya Amarasena, Shyamchand Mayengbam

и другие.

Microorganisms, Год журнала: 2022, Номер 10(6), С. 1168 - 1168

Опубликована: Июнь 7, 2022

B vitamins act as coenzymes in a myriad of cellular reactions. These include energy production, methyl donor generation, neurotransmitter synthesis, and immune functions. Due to the ubiquitous roles these vitamins, their deficiencies significantly affect host's metabolism. Recently, novel homeostasis gut microbial ecology intestinal health continue be unravelled. This review focuses on functional biosynthesis how influence growth proliferation microbiota. We have identified bacteria that can produce biosynthetic mechanisms are presented. The effects vitamin morphology, inflammation, its disorders also discussed.

Язык: Английский

Процитировано

90

Exploring the Immune-Boosting Functions of Vitamins and Minerals as Nutritional Food Bioactive Compounds: A Comprehensive Review DOI Creative Commons
Saikat Mitra,

Shyamjit Paul,

Sumon Roy

и другие.

Molecules, Год журнала: 2022, Номер 27(2), С. 555 - 555

Опубликована: Янв. 16, 2022

Food components have long been recognized to play a fundamental role in the growth and development of human body, conferring protective functionalities against foreign matter that can be severe public health problems. Micronutrients such as vitamins minerals are essential individuals must meet their daily requirements through dietary sources. act immunomodulators protect host immune response, thus preventing evasion by pathogenic organisms. Several experimental investigations undertaken appraise immunomodulatory functions minerals. Based on these findings, this review describes immune-boosting micronutrients mechanisms action which mediated. Deficiencies plasma concentrations lead reduction performance system functioning, representing key contributor unfavorable immunological states. This provides descriptive overview characteristics utilization (vitamins minerals) preventative strategies designed reduce morbidity mortality among patients suffering from invasions or autoimmune disorders.

Язык: Английский

Процитировано

84

Antioxidant, anti-inflammatory and immunomodulatory roles of vitamins in COVID-19 therapy DOI
Aurelia Magdalena Pisoschi,

Aneta Pop,

Florin Iordache

и другие.

European Journal of Medicinal Chemistry, Год журнала: 2022, Номер 232, С. 114175 - 114175

Опубликована: Фев. 4, 2022

Язык: Английский

Процитировано

75

The importance of thiamine (vitamin B1) in humans DOI Open Access
Małgorzata Mrowicka,

Jerzy Mrowicki,

Grzegorz Dragan

и другие.

Bioscience Reports, Год журнала: 2023, Номер 43(10)

Опубликована: Июнь 30, 2023

Thiamine (thiamin, B1) is a vitamin necessary for proper cell function. It exists in free form as thiamine, or mono-, di- triphosphate. plays special role the body coenzyme metabolism of carbohydrates, fats and proteins. In addition, it participates cellular respiration oxidation fatty acids: malnourished people, high doses glucose result acute thiamine deficiency. also energy production mitochondria protein synthesis. needed to ensure functioning central peripheral nervous system, where involved neurotransmitter Its deficiency leads mitochondrial dysfunction, lactate pyruvate accumulation, consequently focal thalamic degeneration, manifested Wernicke's encephalopathy Wernicke-Korsakoff syndrome. can lead severe even fatal neurologic cardiovascular complications, including heart failure, neuropathy leading ataxia paralysis, confusion, delirium. The most common risk factor alcohol abuse. This paper presents current knowledge biological functions its antioxidant properties, effects body.

Язык: Английский

Процитировано

66

Small molecules as cancer targeting ligands: Shifting the paradigm DOI
Navjeet Kaur, Pankaj Popli,

Neha Tiwary

и другие.

Journal of Controlled Release, Год журнала: 2023, Номер 355, С. 417 - 433

Опубликована: Фев. 11, 2023

Язык: Английский

Процитировано

51

Gut Microbiota and Breast Cancer: The Dual Role of Microbes DOI Open Access
Ana I. Álvarez‐Mercado,

Ana del Valle Cano,

Mariana F. Fernández

и другие.

Cancers, Год журнала: 2023, Номер 15(2), С. 443 - 443

Опубликована: Янв. 10, 2023

Breast cancer is the most frequently diagnosed and also one of leading causes mortality among women. The genetic environmental factors known to date do not fully explain risk developing this disease. In recent years, numerous studies have highlighted dual role gut microbiota in preservation host health development different pathologies, them. Our capable producing metabolites that protect homeostasis but can produce molecules with deleterious effects, which, turn, may trigger inflammation carcinogenesis, even affect immunotherapy. purpose review describe mechanisms by which cause general, breast particular, compile clinical trials address alterations or changes women cancer.

Язык: Английский

Процитировано

49

Harnessing Gut Microbiota for Biomimetic Innovations in Health and Biotechnology DOI Creative Commons
Ana Isabel Beltrán-Velasco, Vicente Javier Clemente‐Suárez

Biomimetics, Год журнала: 2025, Номер 10(2), С. 73 - 73

Опубликована: Янв. 24, 2025

The gut microbiota is a complex and dynamic ecosystem that plays fundamental role in human health by regulating immunity, metabolism, the gut–brain axis. Beyond its critical physiological functions, it has emerged as rich source of inspiration for biomimetic innovations healthcare biotechnology. This review explores transformative potential microbiota-based biomimetics, focusing on key biological mechanisms such resilience, self-regulation, quorum sensing. These have inspired development innovative applications, including personalized probiotics, synbiotics, artificial microbiomes, bioinspired biosensors, bioremediation systems. Such technologies aim to emulate optimize intricate functions microbial ecosystems, addressing challenges environmental sustainability. integration advanced technologies, intelligence, bioengineering, multi-omics approaches, further accelerated biomimetics. tools enable precision therapies tailored individual profiles, enhance efficacy diagnostic systems, facilitate design environmentally sustainable solutions, waste-to-energy systems platforms. Emerging areas innovation, gut-on-chip models synthetic biology, offer unprecedented opportunities studying applying principles controlled environments. Despite these advancements, remain. replication complexity environments, ethical concerns regarding genetically engineered microorganisms, equitable access are hurdles must be addressed. underscores importance interdisciplinary collaboration public awareness overcoming barriers ensuring responsible solutions. By leveraging biomimetics represents promising frontier approach revolutionize therapeutic strategies, redefine tools, address global challenges, paving way more personalized, efficient, future medicine

Язык: Английский

Процитировано

2