Global Impacts of Western Diet and Its Effects on Metabolism and Health: A Narrative Review

Nutrients, Год журнала: 2023, Номер 15(12), С. 2749 - 2749

Опубликована: Июнь 14, 2023

The Western diet is a modern dietary pattern characterized by high intakes of pre-packaged foods, refined grains, red meat, processed high-sugar drinks, candy, sweets, fried conventionally raised animal products, high-fat dairy and high-fructose products. present review aims to describe the effect on metabolism, inflammation, antioxidant status; impact gut microbiota mitochondrial fitness; cardiovascular health, mental cancer; sanitary cost diet. To achieve this goal, consensus critical was conducted using primary sources, such as scientific articles, secondary including bibliographic indexes, databases, web pages. Scopus, Embase, Science Direct, Sports Discuss, ResearchGate, Web were used complete assignment. MeSH-compliant keywords “Western diet”, “inflammation”, “metabolic health”, fitness”, “heart disease”, “cancer”, “oxidative stress”, “mental “metabolism” used. following exclusion criteria applied: (i) studies with inappropriate or irrelevant topics, not germane review’s focus; (ii) Ph.D. dissertations, proceedings conferences, unpublished studies. This information will allow for better comprehension nutritional behavior its an individual’s metabolism well national systems. Finally, practical applications derived from are made.

Язык: Английский

---

Ultra-processed food exposure and adverse health outcomes: umbrella review of epidemiological meta-analyses

BMJ, Год журнала: 2024, Номер unknown, С. e077310 - e077310

Опубликована: Фев. 28, 2024

Abstract Objective To evaluate the existing meta-analytic evidence of associations between exposure to ultra-processed foods, as defined by Nova food classification system, and adverse health outcomes. Design Systematic umbrella review meta-analyses. Data sources MEDLINE, PsycINFO, Embase, Cochrane Database Reviews, well manual searches reference lists from 2009 June 2023. Eligibility criteria for selecting studies reviews meta-analyses cohort, case-control, and/or cross sectional study designs. credibility evidence, pre-specified were applied, graded convincing (“class I”), highly suggestive II”), III”), weak IV”), or no V”). The quality was assessed using GRADE (Grading Recommendations, Assessment, Development, Evaluations) framework, categorised “high,” “moderate,” “low,” “very low” quality. Results search identified 45 unique pooled analyses, including 13 dose-response 32 non-dose-response (n=9 888 373). Overall, direct found foods (71%) parameters spanning mortality, cancer, mental, respiratory, cardiovascular, gastrointestinal, metabolic Based on criteria, (class I) supported greater higher risks incident cardiovascular disease related mortality (risk ratio 1.50, 95% confidence interval 1.37 1.63; GRADE=very low) type 2 diabetes (dose-response risk 1.12, 1.11 1.13; moderate), prevalent anxiety outcomes (odds 1.48, 1.59; combined common mental disorder 1.53, 1.43 low). Highly II) indicated that directly associated with all cause 1.21, 1.15 1.27; low), heart (hazard 1.66, 1.51 1.84; 1.40, 1.23 very depressive 1.22, 1.16 1.28; together sleep 1.41, 1.24 1.61; wheezing 1.27 1.55; obesity 1.55, 1.36 1.77; Of remaining 34 21 strength III-IV) V). 22 analyses rated low quality, 19 four moderate Conclusions Greater a outcomes, especially cardiometabolic, disorder, These findings provide rationale develop effectiveness population based public measures target reduce dietary improved human health. They also inform support urgent mechanistic research. registration PROSPERO CRD42023412732.

Язык: Английский

---

Low-Grade Inflammation and Ultra-Processed Foods Consumption: A Review

Nutrients, Год журнала: 2023, Номер 15(6), С. 1546 - 1546

Опубликована: Март 22, 2023

Low-grade inflammation alters the homeostasis of organism and favors onset many chronic diseases. The global growth in prevalence noncommunicable diseases recent years has been accompanied by an increase consumption ultra-processed foods (UPF). Known to be hyperpalatable, economic ready-to-eat, increased UPF already recognized as a risk factor for several Different research groups have tried investigate whether could promote low-grade thus favor development Current evidence highlights adverse health effects characteristics, not only due nutrients provided diet rich UPF, but also non-nutritive components present effect they may on gut health. This review aims summarize available possible relationship between excessive modulation inflammation, potential promoters disease.

Язык: Английский

---

Effects of ultra-processed foods on the microbiota-gut-brain axis: The bread-and-butter issue

Food Research International, Год журнала: 2023, Номер 167, С. 112730 - 112730

Опубликована: Март 21, 2023

Язык: Английский

---

Feeding gut microbes to nourish the brain: unravelling the diet–microbiota–gut–brain axis

Nature Metabolism, Год журнала: 2024, Номер 6(8), С. 1454 - 1478

Опубликована: Авг. 22, 2024

Язык: Английский

---

Ultra-processed foods and human health: An umbrella review and updated meta-analyses of observational evidence

Clinical Nutrition, Год журнала: 2024, Номер 43(6), С. 1386 - 1394

Опубликована: Апрель 18, 2024

Ultra-processed food (UPF) intake has increased sharply over the last few decades and been consistently asserted to be implicated in development of non-communicable diseases. We aimed evaluate update existing observational evidence for associations between ultra-processed consumption human health.

Язык: Английский

---

Higher Ultra-Processed Food Consumption Is Associated with Greater High-Sensitivity C-Reactive Protein Concentration in Adults: Cross-Sectional Results from the Melbourne Collaborative Cohort Study

Nutrients, Год журнала: 2022, Номер 14(16), С. 3309 - 3309

Опубликована: Авг. 12, 2022

Background: Few studies have examined associations between ultra-processed food intake and biomarkers of inflammation, inconsistent results been reported in the small number that do exist. As such, further investigation is required. Methods: Cross-sectional baseline data from Melbourne Collaborative Cohort Study (MCCS) were analysed (n = 2018). We applied NOVA classification system to a frequency questionnaire (FFQ) determine (g/day). The outcome was high-sensitivity C-reactive protein concentration (hsCRP; mg/L). fitted unadjusted adjusted linear regression analyses, with sociodemographic characteristics lifestyle- health-related behaviours as covariates. Supplementary analyses for body mass index (kg/m2). Sex assessed possible effect modifier. Ultra-processed modelled 100 g increments magnitude expressed estimated relative change hsCRP accompanying 95% confidence intervals (95%CIs). Results: After adjustment, every increase associated 4.0% (95%CIs: 2.1−5.9%, p < 0.001). showed part this association independent (estimated hsCRP: 2.5%; 95%CIs: 0.8−4.3%, 0.004). No interaction observed sex intake. Conclusion: Higher cross-sectionally elevated hsCRP, which appeared occur index. Future prospective intervention are necessary confirm directionality whether causal.

Язык: Английский

---

Exploring the Interrelationships between Diabetes, Nutrition, Anxiety, and Depression: Implications for Treatment and Prevention Strategies

Nutrients, Год журнала: 2023, Номер 15(19), С. 4226 - 4226

Опубликована: Сен. 30, 2023

Across the world, diabetes, depression, and anxiety symptoms have gained widespread recognition as significant public health issues. Recent research has unveiled a mutually influential relationship between diabetes these two mental conditions, where each disorder impacts course outcomes of others. The role nutrition emerges pivotal in preventing treating anxiety, diabetes. A thorough literature review was undertaken to investigate reciprocal effects including their impact on development severity condition. Additionally, prevention management related complications at-risk individuals were assessed. Our findings show that disorders, such depression increase risk developing type 2 are associated with poorer glycemic control, increased diabetes-related complications, higher mortality rates. Conversely, is also linked an anxiety. biological, psychological, social factors contribute comorbidity conditions complex multifaceted. Therefore, integrated approach both critical for improving patient reducing overall burden disease. Nutritional interventions should be utilized reduce patients well enhance

Язык: Английский

---

Ultra-processed food consumption and human health: an umbrella review of systematic reviews with meta-analyses

Critical Reviews in Food Science and Nutrition, Год журнала: 2024, Номер unknown, С. 1 - 9

Опубликована: Фев. 16, 2024

Recently, ultra-processed foods received a lot of attention, but also criticism. Our aim was to provide an overview the existing evidence food consumption on human health. We conducted systematic search in four databases until January 5th, 2024. Systematic reviews with meta-analyses as defined by NOVA classification system were included. The certainty evaluated GRADE approach. identified 16 publications. Moderate found for all-cause mortality (Summary Risk Ratio per 50 g: 1.02; 95% confidence Interval (CI): 1.01, 1.03), cardiovascular disease incidence and (per g/d: 1.04; CI: 1.02, 1.06, 1.05; 1.08), type 2 diabetes 10%: 1.12; 1.10, 1.13) colorectal cancer 1.07). For several outcomes such inflammatory bowel diseases, obesity, metabolic syndrome, nonalcoholic fatty liver disease, mental health well nutrient quality, similar estimates observed, limited. Discussing concept, it remains unclear whether processing leads increased risks or if is only measure poor diet quality.

Язык: Английский

---

Association between junk food consumption and mental health problems in adults: a systematic review and meta-analysis

BMC Psychiatry, Год журнала: 2024, Номер 24(1)

Опубликована: Июнь 12, 2024

Abstract Background Anxiety and depression can seriously undermine mental health quality of life globally. The consumption junk foods, including ultra-processed fast unhealthy snacks, sugar-sweetened beverages, has been linked to health. aim this study is use the published literature evaluate how food may be associated with disorders in adults. Methods A systematic search was conducted up July 2023 across international databases PubMed/Medline, ISI Web Science, Scopus, Cochrane, Google Scholar, EMBASE. Data extraction assessment were performed by two independent reviewers. Heterogeneity studies assessed using I 2 statistic chi-square-based Q-test. random/fixed effect meta-analysis pool odds ratios (ORs) hazard (HRs). Results Of 1745 retrieved articles, 17 159,885 participants suitable for inclusion review (seven longitudinal, nine cross-sectional one case-control studies). Quantitative synthesis based on showed that increases having stress (OR = 1.15, 95% CI: 1.06 1.23). Moreover, pooling results cohort a 16% increment developing problems 1.16, 1.07 1.24). Conclusion Meta-analysis revealed foods an increased depression. Increased heightened psychological being experienced adult populations.

Язык: Английский

---