International Journal of Molecular Sciences,
Год журнала:
2023,
Номер
24(10), С. 8738 - 8738
Опубликована: Май 14, 2023
The
development
of
multifunctional
dressing
materials
with
beneficial
properties
for
wound
healing
has
become
a
recent
focus
research.
Many
studies
are
being
conducted
to
incorporate
active
substances
into
dressings
positively
impact
processes.
Researchers
have
investigated
various
natural
additives,
including
plant
extracts
and
apiproducts
such
as
royal
jelly,
enhance
the
dressings.
In
this
study,
polyvinylpyrrolidone
(PVP)-based
hydrogel
modified
jelly
were
developed
analyzed
their
sorption
ability,
wettability,
surface
morphology,
degradation,
mechanical
properties.
results
showed
that
crosslinking
agent
content
had
an
on
physicochemical
hydrogels
potential
use
innovative
materials.
This
study
swelling
behavior,
containing
jelly.
majority
tested
gradual
increase
in
ratio
time.
pH
incubated
fluids
varied
depending
type
fluid
used,
distilled
water
having
greatest
decrease
due
release
organic
acids
from
samples
relatively
homogeneous
surface,
no
dependence
between
composition
morphology
was
observed.
Natural
additives
like
can
modify
hydrogels,
increasing
elongation
percentage
while
decreasing
tensile
strength.
These
findings
suggest
possible
future
applications
fields
requiring
high
flexibility
elasticity.
Materials,
Год журнала:
2024,
Номер
17(2), С. 278 - 278
Опубликована: Янв. 5, 2024
Effective
wound
treatment
has
become
one
of
the
most
important
challenges
for
healthcare
as
it
continues
to
be
leading
causes
death
worldwide.
Therefore,
care
technologies
significantly
evolved
in
order
provide
a
holistic
approach
based
on
various
designs
functional
dressings.
Among
them,
hydrogels
have
been
widely
used
due
their
biocompatibility
and
similarity
extracellular
matrix.
The
hydrogel
formula
offers
control
an
optimal
moisture
level
its
ability
absorb
excess
fluid
from
or
release
needed.
Additionally,
can
successfully
integrated
with
plethora
biologically
active
components
(e.g.,
nanoparticles,
pharmaceuticals,
natural
extracts,
peptides),
thus
enhancing
performance
resulting
composite
healing
applications.
In
this
review,
the-state-of-the-art
discoveries
related
stimuli-responsive
hydrogel-based
dressings
summarized,
taking
into
account
antimicrobial,
anti-inflammatory,
antioxidant,
hemostatic
properties,
well
other
effects
re-epithelialization,
vascularization,
restoration
tissue)
use.
ACS Applied Bio Materials,
Год журнала:
2024,
Номер
7(5), С. 2660 - 2676
Опубликована: Май 9, 2024
Wound
healing,
particularly
for
chronic
wounds,
presents
a
considerable
difficulty
due
to
differences
in
biochemical
and
cellular
processes
that
occur
different
types
of
wounds.
Recent
technological
breakthroughs
have
notably
advanced
the
understanding
diagnostic
therapeutic
approaches
wound
healing.
The
evolution
care
has
seen
transition
from
traditional
textile
dressings
variety
alternatives,
including
self-healing
hydrogels,
hydrofibers,
foams,
hydrocolloids,
environment
responsive
dressings,
growth
factor-based
therapy,
bioengineered
skin
substitutes,
stem
cell
gene
therapy.
Technological
advancements,
such
as
3D
printing
electronic
(e-skin)
contribute
customization
Despite
these
effectively
managing
wounds
remains
challenging.
This
necessitates
development
treatments
consider
performance,
risk–benefit
balance,
cost-effectiveness.
review
discusses
innovative
strategies
healing
Incorporating
biomarkers
into
coupled
with
corresponding
biosensors
drug
delivery
formulations,
enables
theranostic
approach
treatment
Furthermore,
integrating
power
sources
user
interfaces
like
near-field
communication,
radio
frequency
identification,
Bluetooth
enhances
real-time
monitoring
on-demand
delivery.
It
also
provides
thorough
evaluation
advantages,
patient
compliance,
costs,
durability
emphasizing
smart
formulations
their
preparation
methods.
Gels,
Год журнала:
2024,
Номер
10(9), С. 547 - 547
Опубликована: Авг. 23, 2024
Regenerative
hydrogels
from
natural
polymers
have
come
forth
as
auspicious
materials
for
use
in
regenerative
medicine,
with
interest
attributed
to
their
intrinsic
biodegradability,
biocompatibility,
and
ability
reassemble
the
extracellular
matrix.
This
review
covers
latest
advances
used
wound
healing,
focusing
on
chemical
composition,
cross-linking
mechanisms,
functional
properties.
Key
carbohydrate
polymers,
including
alginate,
chitosan,
hyaluronic
acid,
polysaccharide
gums,
agarose,
carrageenan,
xanthan
gum,
are
discussed
terms
of
sources,
structures
specific
properties
suitable
applications.
The
further
explores
categorization
based
ionic
charge,
response
physiological
stimuli
(i.e.,
pH,
temperature)
particularized
roles
tissue
self-healing.
Various
methods
enhance
mechanical
biological
performance
these
also
examined.
By
highlighting
recent
innovations
ongoing
challenges,
this
article
intends
give
a
detailed
understanding
potential
revolutionize
medicine
improve
patient
healing
outcomes.
