Applied Food Research, Год журнала: 2024, Номер 4(2), С. 100492 - 100492
Опубликована: Сен. 6, 2024
Язык: Английский
EBioMedicine, Год журнала: 2024, Номер 103, С. 105118 - 105118
Опубликована: Апрель 13, 2024
BackgroundMicroplastic (MP) pollution has emerged as a significant environmental concern worldwide. While extensive research focused on their presence in marine organisms and ecosystems, potential impact human health, particularly the circulatory system, remains understudied. This project aimed to identify quantify mass concentrations, polymer types, physical properties of MPs thrombi surgically retrieved from both arterial venous systems at three anatomically distinct sites, namely, cerebral arteries brain, coronary heart, deep veins lower extremities. Furthermore, this study investigate association between levels disease severity.MethodsThrombus samples were collected 30 patients who underwent thrombectomy procedures due ischaemic stroke (IS), myocardial infarction (MI), or vein thrombosis (DVT). Pyrolysis–gas chromatography spectrometry (Py-GC/MS) was employed concentrations MPs. Laser direct infrared (LDIR) spectroscopy scanning electron microscopy (SEM) used analyse Demographic clinical information also examined. A rigorous quality control system eliminate contamination.FindingsMPs detected by Py-GC/MS 80% (24/30) obtained with IS, MI, DVT, median 61.75 μg/g, 141.80 69.62 respectively. Among 10 target types MP polymers, polyamide 66 (PA66), polyvinyl chloride (PVC), polyethylene (PE) identified. Further analyses suggested that higher may be associated greater severity (adjusted β = 7.72, 95% CI: 2.01–13.43, p < 0.05). The level D-dimer MP-detected group significantly than MP-undetected (8.3 ± 1.5 μg/L vs 6.6 0.5 μg/L, 0.001). Additionally, LDIR analysis showed PE dominant among 15 identified MPs, accounting for 53.6% all mean diameter 35.6 μm. shapes polymers using SEM found heterogeneous.InterpretationThis presents qualitative quantitative evidence thrombotic diseases through use multimodal detection methods. Higher increased severity. Future larger sample size is urgently needed sources exposure validate observed trends study.FundingThis funded SUMC Scientific Research Initiation Grant (SRIG, No. 009-510858038), Postdoctoral (No. 202205230031-3), 2020 Li Ka Shing Foundation Cross-Disciplinary 2020LKSFG02C).
Язык: Английский
Процитировано
36
Food Chemistry X, Год журнала: 2025, Номер 25, С. 102186 - 102186
Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
3
Journal of Hazardous Materials, Год журнала: 2024, Номер 469, С. 133963 - 133963
Опубликована: Март 6, 2024
Язык: Английский
Процитировано
17
The Science of The Total Environment, Год журнала: 2024, Номер 929, С. 172680 - 172680
Опубликована: Апрель 23, 2024
Язык: Английский
Процитировано
15
Russian Chemical Reviews, Год журнала: 2025, Номер 94(3), С. RCR5155 - RCR5155
Опубликована: Март 1, 2025
The presence of microplastics (MPs) in the environment is a highly relevant and aggravating environmental problem, which concern not only for specialists various fields but also everyone who cares about future Earth. ever-increasing production polymers expanding use plastic products enlarged MP concentrations Earth's ecosystem. need to control accumulation spread MPs caused by current crisis where no microplastic-free areas have remained on number studies dealing with existing potential threat living organisms from consumption increasing every year. aim this review systematize available information occurrence briefly describe main types polymer materials acting as sources mechanisms formation transport environment. hazardous behaviour analyzed considering their impact physiology aquatic soil organisms. Special emphasis demonstrating adverse effect emissions 3D printing materials. An overview methods capture given facilitate analysis development more reliable removal disposal. As result review, we assess long-term human health consequences exposure. Understanding formation, lifecycle environment, ways interaction will controlling design implementation effective techniques remediation prevent ecological consequences. <br>The bibliography includes 244 references.
Язык: Английский
Процитировано
2
Aquatic Toxicology, Год журнала: 2024, Номер 272, С. 106944 - 106944
Опубликована: Май 9, 2024
Язык: Английский
Процитировано
8
Journal of the European Academy of Dermatology and Venereology, Год журнала: 2025, Номер unknown
Опубликована: Янв. 21, 2025
Abstract Hazards to human and planetary health are present at every stage of the plastic life cycle, yet production is projected triple by 2060. This review focuses on three key areas: cycle plastic, impact microplastics their associated chemicals, along with recommendations reduce use. In dermatology, micro‐ nanoplastics especially problematic as they in over 90% personal care products. They have been detected utero, absorbed through skin found lungs gastrointestinal tract. Numerous vitro animal studies substantiated negative but gaps remain regards effect health. spite this limitation, we evidence date offer evidence‐based which can production, enhance outcomes promote environmental justice.
Язык: Английский
Процитировано
1
Emerging contaminants, Год журнала: 2024, Номер unknown, С. 100417 - 100417
Опубликована: Сен. 1, 2024
Язык: Английский
Процитировано
4
Environment International, Год журнала: 2024, Номер 193, С. 109109 - 109109
Опубликована: Ноя. 1, 2024
Micro/Nano plastics (MNPs) pollutants are widespread in the environment, raising significant concerns about their biosafety. Emerging studies indicate that urinary system is a primary accumulation site for MNPs, leading to severe tissue and functional damage. This review aims summarize recent research on potential hazards MNPs may pose system, highlighting mechanisms of toxicity current state knowledge. Studies have shown enter human body through drinking water, food chain, inhalation, skin contact. They penetrate bloodstream via digestive, respiratory, systems, subsequently dispersing various organs, including system. The might induce cellular oxidative stress, inflammation, apoptosis, autophagy, "intestine-kidney axis", other possible toxic mechanisms. These processes could disrupt kidney metabolic functions promote fibrosis, thereby potentially increasing risk diseases. Despite ongoing research, understanding MNPs' impact remains limited. Therefore, this provides comprehensive overview highlights key challenges, outlines future directions. It offers theoretical basis development effective protective measures policies.
Язык: Английский
Процитировано
4
Toxics, Год журнала: 2024, Номер 12(7), С. 463 - 463
Опубликована: Июнь 26, 2024
In order to visualize the content and development patterns of microplastic biodegradation research, American Chemical Society (ACS), Elsevier, Springer Link, for Microbiology (ASM) were searched years 2012-2022 using Citespace VOSvivewer bibliometrics visual analysis. The processes mechanisms microplastics reviewed on this basis. results showed a sharp increase in number publications between 2012 2022, peaking 2020-2021, with 62 more than previous decade. University Chinese Academy Sciences (UCAS), Northwest A&F (NWAFU), Agricultural (CAAS) are top three research institutions field. Researchers mainly located China, United States America (USA), India. Furthermore, field is primarily concerned screening functional microorganisms, determination enzymes, analysis mechanisms. These studies have revealed that existing microorganisms bacteria, predominantly Proteobacteria Firmicutes; fungi, Ascomycota; some intestinal microorganisms. main enzymes secreted process hydrolase, oxidative, depolymerization enzymes. Microorganisms degrade through colonization, biofilm retention, bioenzymatic degradation. elucidated current status problems microbial degradation microplastics, provide direction further molecular mechanism
Язык: Английский
Процитировано
3