Scientific Reports,
Год журнала:
2025,
Номер
15(1)
Опубликована: Фев. 13, 2025
Fertilizer
application
is
a
common
agricultural
practice
that
enhances
soil
fertility
but
can
also
increase
heavy
metal
mobility
in
contaminated
soils.
This
study
used
pot
experiment
with
four
vegetables
(water
spinach,
Chinese
cabbage,
lettuce,
and
garland
chrysanthemum)
to
evaluate
the
impact
of
BC,
ZE,
their
combination
(CO)
on
Cd
Pb
levels
under
different
fertilization
schemes.
Results
showed
CO
treatment
significantly
enhanced
enzyme
activities,
increasing
urease
by
2.6–31.6%
catalase
1.37–14.24%
varying
fertilizer
conditions.
However,
sucrase
activity
increased
only
compound
fertilizers.
The
use
fertilizers
alone
raised
vegetable
shoots
0.65
mg·kg⁻¹
12.76
mg·kg⁻¹,
respectively,
while
amendment
effectively
mitigated
these
increases.
BCR
sequential
extraction
indicated
BC
shifted
into
more
stable
fractions,
reducing
bioavailability.
Specifically,
reduced
accumulation
24.8–49.7%,
showing
particular
efficacy
levels.
These
findings
highlight
particularly
combination,
offer
an
effective
strategy
for
remediating
metal-contaminated
soils
systems,
especially
when
chemical
are
used.
International Journal of Environmental Research and Public Health,
Год журнала:
2024,
Номер
21(4), С. 468 - 468
Опубликована: Апрель 11, 2024
Background:
Exposure
to
environmental
pollutants
such
as
metals
and
Per-
Polyfluoroalkyl
Substances
(PFAS)
has
become
common
increasingly
associated
with
a
decrease
in
the
estimated
Glomerular
Filtration
Rate
(eGFR),
which
is
marker
often
used
measure
chronic
kidney
disease
(CKD).
However,
there
are
limited
studies
involving
use
of
both
eGFR
urine
albumin
creatinine
ratio
(uACR),
more
comprehensive
markers
determine
presence
CKD
complexity
pollutant
exposures
response
interactions,
especially
for
combined
PFAS,
not
been
comprehensively
elucidated.
Objective:
This
study
aims
assess
individual
effects
perfluorooctanoic
acid
(PFOA),
perfluorooctanesulfonic
(PFOS),
Cadmium
(Cd),
Mercury
(Hg),
Lead
(Pb)
exposure
on
using
data
from
National
Health
Nutritional
Examination
Survey
(NHANES)
2017–2018.
Methods:
We
employed
bivariate
logistic
regression
Bayesian
Kernel
Machine
Regression
(BKMR)
our
analysis
data.
Results:
Logistic
results
revealed
positive
association
between
PFOA
CKD.
Our
BKMR
non-linear
bi-phasic
relationship
metal
In
univariate
exposure–response
function
plot,
Cd
Hg
exhibited
U
N-shaped
interaction,
indicated
non-additive
low
high
addition,
two
mixture
that
had
U-shaped
at
different
quantiles
Pb,
Hg,
PFOA,
PFOS,
indicating
levels
CKD,
implying
complex
biological
interaction.
Hg’s
interaction
plot
demonstrated
across
all
Cd,
75th
quantile
Pb
50th
PFOS.
Furthermore,
PIP
underscored
Cd’s
consistent
(PIP
=
1.000)
followed
by
0.9984),
then
PFOS
closely
related
0.7880
0.7604,
respectively,
finally
0.6940),
contributing
least
among
five
though
significant.
Conclusions:
findings
pollutants,
particularly
These
highlight
need
public
health
interventions
strategies
mitigate
cumulative
effect
PFAS
elucidate
significance
utilizing
advanced
statistical
methods
tools
understand
impact
human
health.
Further
research
needed
mechanistic
pathways
metal-induced
injury
longitudinal
required
ascertain
long-term
these
exposures.
F1000Research,
Год журнала:
2025,
Номер
14, С. 134 - 134
Опубликована: Янв. 27, 2025
Heavy
metal
contamination
has
gradually
become
a
very
much
important
significant
global
issue
due
to
its
continual
existence
in
the
environment
and
bioaccumulation
ecosystems,
posing
deleterious
risks
human
health.
This
review
aims
investigate
sources,
pathways,
toxicological
impacts
of
heavy
metals
such
as
cadmium,
lead,
mercury,
arsenic,
elucidating
their
health
consequences
plausible
mitigation
strategies.
Furthermore,
explores
dual
origins
contamination;
natural
geological
processes
anthropogenic
activities
industrial
emissions,
mining,
agricultural
practices.
These
sip
into
soil,
water,
food
chains,
leading
bioaccumulation,
bio-magnification
causing
risks,
including
cardiovascular
diseases,
neurological
disorders,
reproductive
toxicity.
Additionally,
addition
indigenous
case
studies
from
Nigeria,
lead
poisoning
Zamfara
State
Great
Kwa
River
Cross
Rivers
underscores
disproportionate
impact
pollution
developing
nations.
reveal
socio-economic
environmental
dimensions
issue,
providing
contextual
understanding
region-specific
vulnerabilities
outcomes.
To
address
these
problems,
evaluates
already
existing
strategies,
chelation
therapy
phytoremediation,
while
proposing
sustainable,
cost-effective
solutions
for
reducing
exposure
mitigating
impacts.
It
emphasizes
importance
integrative
approaches
involving
policy,
community
engagement,
technological
innovations
fight
effectively.
In
conclusion,
this
seminar
contributes
toxicity,
giving
showcasing
insights
sources
implications
contamination.
By
integrating
theoretical
perspectives
with
practical
solutions,
provides
robust
framework
informing
policy
makers
advancing
sustainable
management
practices.
International Journal of Environmental Research and Public Health,
Год журнала:
2022,
Номер
19(13), С. 7905 - 7905
Опубликована: Июнь 28, 2022
Assessment
of
indoor
air
quality
is
especially
important,
since
people
spend
substantial
amounts
time
indoors,
either
at
home
or
work.
This
study
analyzes
concentrations
selected
heavy
metals
in
40
dust
samples
obtained
from
houses
the
highly-industrialized
Asaluyeh
city,
south
Iran
spring
and
summer
seasons
(20
each).
Furthermore,
health
risk
due
to
exposure
pollution
investigated
for
both
children
adults,
a
city
with
several
oil
refineries
petrochemical
industries.
The
chemical
analysis
revealed
that
followed
order
Cr
>
Ni
Pb
As
Co
Cd.
A
significant
difference
was
observed
potential
toxic
elements
(PTEs)
such
as
Cr,
Ni,
mean
(±stdev)
levels
were
60.2
±
9.1
mg
kg−1,
5.6
2.7
kg−1
16.4
1.9
respectively,
while
significantly
lower
(17.6
9.7
3.0
1.7
13.5
2.4
respectively).
Although
hazard
index
(HI)
values,
which
denote
possibility
non-carcinogenic
household
metals,
generally
low
adults
(HI
<
1),
carcinogenic
risks
arsenic
chromium
found
be
above
safe
limit
1
×
10−4
through
ingestion
pathway,
indicating
high
cancer
Asaluyeh,
summer.
Toxics,
Год журнала:
2022,
Номер
10(8), С. 472 - 472
Опубликована: Авг. 13, 2022
Dietary
assessment
reports
and
population
surveillance
programs
show
that
chronic
exposure
to
low
levels
of
environmental
cadmium
(Cd)
is
inevitable
for
most
people,
adversely
impacts
the
health
children
adults.
Based
on
a
risk
model
considers
an
increase
in
excretion
β2-microglobulin
(β2M)
above
300
μg/g
creatinine
be
“critical”
toxicity
endpoint,
tolerable
intake
level
Cd
was
set
at
0.83
µg/kg
body
weight/day,
urinary
rate
5.24
µg/g
considered
threshold
level.
The
aim
this
review
draw
attention
many
other
endpoints
are
both
clinically
relevant
more
appropriate
derive
limits
than
β2M
endpoint.
In
present
review,
we
focus
reduction
glomerular
filtration
diminished
fecundity
because
low-dose
Cd,
reflected
by
its
as
0.5
creatinine,
have
been
associated
with
dose-dependent
increases
these
pathological
symptoms.
Some
protective
effects
nutritionally
essential
elements
selenium
zinc
highlighted.
Cd-induced
mitochondrial
dysfunction
discussed
potential
mechanism
underlying
gonadal
toxicities
infertility.
Journal of Applied Toxicology,
Год журнала:
2023,
Номер
44(1), С. 129 - 147
Опубликована: Авг. 16, 2023
Abstract
Cadmium
(Cd)
is
a
ubiquitous
heavy
metal
toxicant
with
no
biological
function
in
the
human
body.
Considerably,
because
of
its
long
half‐life
and
very
low
excretion
rate,
Cd
inclined
to
accumulate
cause
deleterious
effects
on
various
body
organs
(e.g.,
liver,
kidney,
ovary)
humans
animals.
Ovaries
are
most
vulnerable
targets
toxicity.
has
been
shown
induce
oxidative
stress,
follicular
atresia,
hormonal
imbalance,
impairment
oocyte
growth
development.
Moreover,
toxicity
associated
increasing
incidences
menstrual
disorders,
pregnancy
loss,
preterm
births,
delayed
puberty,
female
infertility.
Therefore,
it
crucial
understand
how
poisoning
impacts
specific
ovarian
processes
for
development
preventive
interventions
enhance
fertility.
The
current
review
attempts
collate
recent
findings
Cd‐induced
apoptosis,
steroid
synthesis
inhibition,
teratogenic
toxicity,
along
their
possible
mechanisms
tissue
different
animal
species.
Additionally,
also
summarizes
studies
related
use
many
antioxidants,
medicinal
herbs,
other
compounds
as
remedial
approaches
managing