Medically Related Post-traumatic Stress in Children and Adolescents with Congenital Heart Defects

Frontiers in Pediatrics, Год журнала: 2017, Номер 5

Опубликована: Фев. 13, 2017

Children and adolescents with a congenital heart defect (ConHD) frequently undergo painful or frightening medical procedures hospitalizations. They often need multiple invasive at very young age require regular checkups during their entire life. From other pediatric populations it is known that these kind of experiences can result in acute stress reactions even posttraumatic disorder (PTSD) the long-term. PTSD also subthreshold lead to serious (psychosocial) impairment. However, limited information available about children ConHD. Therefore, aim this review provide summary current literature on ConHD describing prevalence its predictors/correlates. This indicates range 12-31% undergoing cardiac surgery develops PTSD. A 12-14% shows elevated symptoms (PTSS). These findings are comparable those hospitalized without Noteworthy, most studies used varying self-report questionnaires measure only one study semi-structured interview. Although all point same direction PTSS, systematic research necessary be able draw firm conclusions. At present, as far we know, clinics treating patients there no screening for In reviewed literature, strong consensus PTSS (preventive) psychological care urgently needed

Язык: Английский

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Post‐traumatic stress as a determinant of quality of life in pediatric solid‐organ transplant recipients

Pediatric Transplantation, Год журнала: 2021, Номер 25(4)

Опубликована: Март 26, 2021

Living with end-stage organ failure is associated an accumulation of traumatic medical events, and despite recovery after solid-organ transplantation (SOT), many children continue to exhibit lower quality life (QOL). Few studies have examined the relationship between post-traumatic stress disorder (PTSD) QOL among pediatric SOT recipients. We conducted a retrospective, cross-sectional review 61 recipients (12 heart, 30 kidney, 19 liver) evaluate association PTSD self-reported QOL. was measured by Child Trauma Screening Questionnaire (CTSQ), using PedsQL Transplant Module (PedsQL-TM) surveys. Demographics, baseline, contemporaneous factors were tested for independent association. 15.2 (12.1-17.6) years old at survey completion. Median CTSQ score 2 (1-3), highest in kidney recipients, 13% identified as high risk PTSD. 83 (70-91) significantly (r = -.68, p < .001). 89 (83-95) similarly -.64, Age time surveys presence any disability also independently PedsQL-TM, respectively. When adjusted Emotional Functioning, remained subscores -.65, symptoms are major modifiable factor self-perceived represent potentially important target post-transplant rehabilitation. Additional research needed understand root contributors potential treatments this population.

Язык: Английский

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Stem cell therapy for cardiac regeneration: key points

Cell and Organ Transplantology, Год журнала: 2024, Номер 12(1)

Опубликована: Май 30, 2024

Cardiovascular diseases are a leading cause of disability and mortality among the working population, necessitating development implementation new, more effective treatment rehabilitation methods for such patients, including use modern cellular tissue technologies. In this review, an analysis summary research results over past decades regarding effectiveness various types stem cells in heart pathology were conducted. Priority directions include search accessible safe sources cells, new their cultivation, scaffolds transplantation. Given pathogenetic mechanisms cardiovascular myocardial regeneration, particular interest clinical application is drawn to tissue-specific progenitors from myocardium replacing injured cardiomyocytes, endothelial correcting accompanying dysfunction, multipotent mesenchymal origins with low immunogenicity that exhibit trophic, anti-inflammatory, immunomodulatory, anti-apoptotic effects. Questions optimal method, dose, frequency cell administration, as well standardization criteria quality effectiveness, remain open. Additionally, combined different may serve priority strategy assessing safety therapy, especially considering paradigm repeated The successful translation obtained preclinical into further large, well-planned, placebo-controlled trials will enhance therapy diseases, which one current challenges regenerative medicine.

Язык: Английский

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Hybrid delivery of behavioral health screening and prevention intervention for pediatric heart transplant recipients and families: A randomized pilot study

Pediatric Transplantation, Год журнала: 2023, Номер 27(8)

Опубликована: Авг. 10, 2023

A significant number of pediatric heart transplant recipients and their families experience post-traumatic stress symptoms following transplantation, which can impact recipient behavioral medical health outcomes. Preventive interventions may improve outcomes, especially if be delivered at a distance to decrease barriers mental care. This pilot study examined the acceptability accessibility an evidence-informed resilience training program using video telehealth platform. secondary aim was assess preliminary efficacy intervention on perceived medication adherence, parent family functioning.

Язык: Английский

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Psychological Health of the Adolescent Transplant Recipient

Pediatric Transplantation, Год журнала: 2024, Номер 28(6)

Опубликована: Авг. 12, 2024

Solid organ transplant recipients experience a period of unique vulnerability during adolescence, when normative developmental changes intersect with health-related variables to influence psychological health.

Язык: Английский

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Ethical and practical dilemmas in cardiac transplantation in infants: a literature review

European Journal of Pediatrics, Год журнала: 2021, Номер 180(8), С. 2359 - 2365

Опубликована: Май 6, 2021

Язык: Английский

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Associations between executive functioning, personality, and posttraumatic stress symptoms in adolescent solid organ transplant recipients

Pediatric Transplantation, Год журнала: 2021, Номер 26(2)

Опубликована: Ноя. 1, 2021

Pediatric solid organ transplant recipients are susceptible to posttraumatic stress symptoms (PTSS), given the presence of a life-threatening chronic medical condition and potential for complications. However, little is known about what individual characteristics associated with an increased risk PTSS among youth who received transplant. The aim current study was evaluate its associations executive functioning (EF) personality (i.e., neuroticism conscientiousness) adolescents transplants.Fifty-three (Mage = 16.40, SD 1.60) kidney, heart, or liver completed self-report measures personality, whereas caregivers caregiver-proxy report adolescent EF.Twenty-two percent reported clinically significant levels PTSS. Higher EF difficulties levels, lower conscientiousness were significantly higher (rs -.34 .64). Simple slope analyses revealed that both high impairment demonstrated highest (t 3.47; p < .001).Most in present did not PTSS; however, those greater may be particularly vulnerable following transplantation. Following transplantation, providers should assess factors developing Identification at critical, strong between certain outcomes (e.g., medication nonadherence) these youth.

Язык: Английский

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Implementation and analysis of clinic administered behavioural health screen in an outpatient paediatric cardiology clinic

Cardiology in the Young, Год журнала: 2024, Номер unknown, С. 1 - 8

Опубликована: Окт. 4, 2024

Abstract Previous studies investigating behavioural health screening processes have focused on selected diagnoses within paediatric cardiology and a smaller number of potential concerns. We developed administered brief survey in our heart centre to assess the presence wider variety concerns connect patients with resources. A cohort 305 aged 2–29 years ( M = 11.97 years; SD 6.00 50.49% female), representing indications for clinic visit, or parent, completed 14 common Behavioural were included based practice patterns psychology. Respondents indicated if they currently receiving services interested follow-up. Surveys during check collected by staff. provider attempted reach all those who interest phone. Approximately 45% sample endorsed one more 30.16% at least concern but not already connected services. Only 27.17% this group requested Most commonly anxiety, sleep problems, depressed/irritable mood, somatic complaints. Survey results converge existing literature indicate that are among youth seen most appropriate Screening programmes can help meet need challenges remain. Clinical implications future directions discussed.

Язык: Английский

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Risk Factors of Post‐Traumatic Stress in Pediatric Solid Organ Transplant Recipients

Pediatric Transplantation, Год журнала: 2024, Номер 28(7)

Опубликована: Сен. 15, 2024

ABSTRACT Background Life with end‐stage organ failure is accompanied by an accumulation of traumatic medical or surgical experiences. Despite recovery after solid transplantation (SOT), many children and adolescents develop post‐traumatic stress symptoms (PTSS). PTSS remain underappreciated as a major comorbidity in SOT programs, despite their association decreased quality life. Methods We conducted retrospective, cross‐sectional study 86 pediatric recipients (17 heart, 44 kidney, 25 liver) to evaluate potential determinants PTSS. Trauma were measured the Child Screening Questionnaire (CTSQ). Demographic, baseline, contemporaneous factors tested for independent CTSQ scores. Results The median post‐transplant score was 2 (IQR 1–4), 22% identified high risk (score ≥5) PTSD. Higher scores independently associated number ICU days within previous 12 months, medications (complexity), involvement foster care primary model ( R [adj.] = 0.26). addition Family Impact Module improved overall 0.33), wherein higher family functioning lower An exploratory analysis pre‐transplant patients n 34) found 1–6), suggesting that are onset before transplant persist afterward. Conclusions highly prevalent population. Risk include recent adverse experiences complexity, whereas stability may be protective. Additional research needed improve early ascertainment support at developing throughout journey.

Язык: Английский

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Unveiling the Psychosocial Impact: Pediatric Organ Transplantation and Posttraumatic Stress Disorders: A Systematic Review.

Experimental and Clinical Transplantation, Год журнала: 2024, Номер 22(Suppl 5)

Опубликована: Окт. 1, 2024

This systematic review delves into the intricate relationship between pediatric organ transplantation and posttraumatic stress disorder, shedding light on interventions crucial for addressing psychosocial well-being of young transplant recipients. multifaceted nature disorder in context examined effects mental health We aimed to studies among patients who have had or were waiting systematically analyze results these studies.

Язык: Английский

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