Evaluating implementation of NCCN guideline-directed genetic screening recommendations for patients with pancreatic ductal adenocarcinoma DOI
Aditya Ghosh, Sheena Bhushan, Oluseyi Abidoye

et al.

Cancer Causes & Control, Journal Year: 2023, Volume and Issue: 35(4), P. 679 - 684

Published: Nov. 28, 2023

Language: Английский

Rates of Routine Cancer Screening and Diagnosis Before vs After the COVID-19 Pandemic DOI Open Access
Allison H. Oakes,

Kelly Boyce,

Catherine Patton

et al.

JAMA Oncology, Journal Year: 2022, Volume and Issue: 9(1), P. 145 - 145

Published: Nov. 17, 2022

This cross-sectional study analyzes patterns in the rates of routine screening and diagnosis for breast, cervical, colorectal cancer before after COVID-19 pandemic.

Language: Английский

Citations

48

Impact of the COVID-19 Pandemic on Histopathological Cancer Diagnostics in Lower Silesia: A Comparative Analysis of Prostate, Breast, and Colorectal Cancer from 2018 to 2022 DOI Open Access
Danuta Szkudlarek, Katarzyna Kalinowska, Benita Wiatrak

et al.

Cancers, Journal Year: 2025, Volume and Issue: 17(1), P. 134 - 134

Published: Jan. 3, 2025

Background/Objective: The COVID-19 pandemic significantly disrupted healthcare systems worldwide including cancer diagnostics. This study aimed to assess the impact of on histopathological diagnostics in Lower Silesia, Poland, specifically focusing prostate, breast, and colorectal cases from 2018 2022. objective was evaluate diagnostic volumes trends before, during, after understand effect disruptions detection. Methods: Histopathological cytological data were collected multiple laboratories across Silesia. Samples categorized into three periods: pre-pandemic (January 2018–February 2020), (March 2020–May 2022), post-pandemic (June–December 2022). Statistical analyses included comparisons positive diagnoses these periods. Results: A significant reduction number examinations occurred during pandemic, particularly its early phase. decline accompanied by a higher frequency diagnoses, suggesting prioritization high-risk cases. Post-pandemic, activity showed partial recovery, though it remained below levels, with notable differences types. Conclusions: delaying detection highlighting system vulnerabilities. These findings underscore importance resilient that can ensure continuity essential services address inequalities access care crises.

Language: Английский

Citations

0

Diagnostic Challenges of Medullary Carcinoma of the Small Intestine During the COVID-19 Pandemic DOI Open Access
Danuta Szkudlarek, Katarzyna Skórkowska-Telichowska, Benita Wiatrak

et al.

Journal of Clinical Medicine, Journal Year: 2025, Volume and Issue: 14(2), P. 298 - 298

Published: Jan. 7, 2025

Background: Medullary carcinoma of the small intestine is an exceptionally rare subtype gastrointestinal cancer, characterized by its solid growth pattern and lack glandular structures, which complicate timely diagnosis. During COVID-19 pandemic, diagnostic delays for cancers became increasingly common due to prioritization COVID-related cases patient reluctance seek medical attention. Methods Result: We present case a 70-year-old male initially misdiagnosed with COVID-19, whose persistent symptoms led eventual discovery medullary carcinoma. Imaging studies revealed focal lesions in liver, spleen, thickened intestinal walls, prompting surgical resection 16 cm segment. Histopathological examination confirmed lymph node liver metastases, supported immunohistochemistry, showed positive markers (calretinin, pancytokeratin, cytokeratin 7) excluded other malignancies. Conclusions: The delay, exacerbated highlights challenges distinguishing from more conditions during global health crises. This underscores importance advanced techniques, such as accurate identification. Maintaining robust cancer pathways emergencies crucial avoid treatment. Future research should focus on improving screening methods developing resilient healthcare systems mitigate similar future

Language: Английский

Citations

0

SARS-CoV-2 primary and breakthrough infections in patients with cancer: Implications for patient care DOI Creative Commons

Lindsey Wang,

William Wang, Rong Xu

et al.

Best Practice & Research Clinical Haematology, Journal Year: 2022, Volume and Issue: 35(3), P. 101384 - 101384

Published: Sept. 1, 2022

Initial reports of SARS-CoV-2 caused COVID-19 suggested that patients with malignant diseases were at increased risk for infection and its severe consequences. In order to provide early United States population-based assessments primary infections in unvaccinated hematologic malignancies or cancer, breakthrough vaccinated we conducted retrospective studies using two, unique nationwide electronic health records (EHR) databases. Using these massive databases highly statistically significant data, our demonstrated that, compared without malignancies, was all cancers malignancies. Risks varied specific types malignancy. Patients cancer greatest during the first year after diagnosis. Risk 65 years older, younger among Black white patients. When against SARS-CoV-2, their decreased relative but remained elevated Compared malignancy showed earlier post vaccination time points. As infections, cancer. There no signs racial disparities These results population basis understand significance subsequent immunologic showing defective delayed immunoresponsiveness vaccines cancers. further recommendations regarding vaccination, vigilance maintaining mitigation strategies

Language: Английский

Citations

9

Detrimental effect of COVID-19 pandemic on patients with extremity bone sarcoma. Reference center experience. DOI Creative Commons
Paweł Teterycz, Bartłomiej Szostakowski, Magdalena Rosińska

et al.

European Journal of Surgical Oncology, Journal Year: 2024, Volume and Issue: 50(10), P. 108604 - 108604

Published: Aug. 13, 2024

1 BACKGROUND: COVID-19 pandemic had a major impact on the healthcare system globally. This work aims to evaluate local treatment in bone sarcoma treated single, high-throughput institution. 2 METHODS: We have analyzed outcomes (i.e., possibility of limb sparing surgery) all patients between January 2016 and November 2022 main reference center Poland. Patients 2016-2019 period were regarded as "pre-pandemic" group, 2020-2022 - "pandemic". Mann-Whitney U Chi-square tests used statistical analysis. No correction for multiple testing was applied. Tests with p < 0.05 deemed significant. 3 RESULTS: There 302 eligible identified. The group characteristics are presented table 1. no differences patient-related variables histological subtypes tumors two groups. tumor size did not differ (p = 0.053), when grades considered, but high grade larger "pandemic" 0.034). reflected percentage surgeries which dropped from 83.3 % 68.2 ("pre-pandemic" vs. "pandemic", 0.004). difference even more stark case 78 54 respectively 0.001). 4 CONCLUSION: To our knowledge, this is first report long lasting oncologic malignant tumors.

Language: Английский

Citations

1

Evaluating Implementation of NCCN Guideline-Directed Genetic Screening Recommendations for Patients with Pancreatic Ductal Adenocarcinoma DOI Creative Commons
Aditya Ghosh, Sheena Bhushan, Oluseyi Abidoye

et al.

Research Square (Research Square), Journal Year: 2023, Volume and Issue: unknown

Published: July 27, 2023

Abstract Purpose In 2019, the National Comprehensive Cancer Network (NCCN) recommended genetic testing for all patients with pancreatic ductal adenocarcinoma (PDAC). To evaluate status of implementation these guidelines in a loco-regional setting, we performed retrospective, observational study among newly diagnosed PDAC who received oncologic care at Northeast Georgia Medical Center Georgia. Methods Chart abstraction from January 1, 2020 to December 31, 2021, was include information on recommendation and completion, time diagnosis testing. The deidentified dataset then analyzed using appropriate descriptive associative statistical Results Of cohort 109 patients, 32 (29.4%) completed screening; 16 (14.7%) were screened within 10 days diagnosis. Among 77 (70.6%) did not receive screening, 45 (41.3%) screening despite treatment intent standard therapy. However, conjunction desire pursue palliative care/hospice/or due terminal illness. Conclusions highlighted gap NCCN guideline-directed as only third underwent suggesting need systematic processes facilitate test more likely be if done early course, especially soon after Research is needed explore discussing large proportion are terminally ill where would potentially benefit family members.

Language: Английский

Citations

1

Evaluación del impacto en la salud: Impacto de la pandemia por COVID-19 en morbilidad en Navarra: Impacto de la pandemia por COVID-19 en los programas de cribado poblacional de cáncer en Navarra DOI Open Access

María Ederra Sanz,

María Rodrigo Olave,

L Po - Aguinaga

et al.

Gobierno de Navarra eBooks, Journal Year: 2023, Volume and Issue: unknown, P. 683 - 692

Published: June 22, 2023

La pandemia por COVID-19 en Navarra ha impactado tanto la atención de los pacientes infectados SARS-CoV-2 como cantidad servicios salud provistos y manera proveerlos, incluyendo prevención, tratamiento seguimiento con cáncer. En Navarra, situación programas detección precoz cáncer mama (PDPCM) colorrectal (PDPCCR) se vio comprometida durante 2020. Durante el periodo confinamiento suspendieron ambos (la realización mamografías envío kits, respectivamente), para evitar un riesgo adicional las personas invitadas a participar profesionales, además necesidad dedicar muchos recursos asistenciales, profesionales físicos COVID-19. 2020 cobertura invitación del PDPCM redujo casi mitad PDPCCR l una cuarta parte, sin que participación viese afectada. El programa cuello útero (PDPCCU), estaba fase diseño antes pandemia, interrumpió debido destinar todos informáticos pandemia. Tras desescalada, aunque mucho esfuerzo, fue progresivamente recuperando actividad anteriormente funcionamiento, retomó PDPCCU.

Citations

1

Negotiating cancer alone: A qualitative study exploring care experiences of racially and ethnically diverse women diagnosed with breast cancer during COVID-19 DOI Creative Commons
Isabel Martinez Leal, Chiara Acquati, Anastasia Rogova

et al.

Journal of Health Psychology, Journal Year: 2023, Volume and Issue: 29(5), P. 367 - 381

Published: Nov. 27, 2023

COVID-19 has critically impacted cancer care services including reduced screenings, diagnoses, and surgeries; particularly among Black Latina/x women who already suffer worse outcomes. This qualitative study explored the experiences of a diverse sample breast survivors ( N = 21; 7 Black, 4 Hispanic, 10 White) undergoing treatment during pandemic via online semi-structured interviews. Grounded theory analysis yielded core category “ negotiating alone,” that included: (1) psychological distress, trajectory in isolation; (2) provider/healthcare system diagnostic delays; (3) heightened anxiety about delays causing progression; (4) supportive limitations; (5) disparate disruptions. described greater care, financial challenges, complications, insurance limitations than White women. The identifies patients’ pandemic-related psychological, healthcare system, health equity challenges suggests recommendations to support their increased needs oncologic

Language: Английский

Citations

1

Adult cancer patients’ barriers to and satisfaction with care at a National Cancer Hospital in Vietnam DOI Creative Commons
Thinh Toan Vu, Marina Weiss,

Linh Thi‐Hoai Nguyen

et al.

PLoS ONE, Journal Year: 2024, Volume and Issue: 19(5), P. e0303157 - e0303157

Published: May 9, 2024

Study objective This study assessed the overall satisfaction with oncological care, including barriers to and identified its associated predictors among adult cancer patients in Vietnam. Methods In this cross-sectional study, we enrolled 300 receiving inpatient care at a large urban hospital between June July 2022. Multivariable linear regression analyses examined associations patient experiences ratings care. Results The mean was 8.82 out of 10, 98.0% recommending facility their friends family. an adjusted model, being female (β = 0.29, 95%CI: 0.04, 0.53), endorsing patient-nurse communication 0.33, 0.13, patient-doctor 0.40, 0.11, 0.70), psychoeducation about medication management 0.30, 0.14, 0.45) were positively ratings. contrast, individuals delays treatment scheduling reported lower -0.38, -0.64, -0.13). Patients perceived health system, social/environmental, individual care: worries income loss due attending (43.3%); fear, depression, anxiety, distress (36.8%); concerns affordability (36.7%) transportation problems (36.7%); excessive waiting times for appointments (28.8%). Conclusion showed high quality. Patient-centered strategies may be targeted further enhance experience. Raising awareness options services, integrating mental into ameliorate facilitate greater processes.

Language: Английский

Citations

0

Effects of the Coronavirus disease 2019 pandemic on mortality in patients with lung cancer: A multiple mediation analysis in Japan DOI Creative Commons
Daisuke Miyamori, Tsukasa Kamitani, Shuhei Yoshida

et al.

International Journal of Cancer, Journal Year: 2024, Volume and Issue: 155(8), P. 1422 - 1431

Published: May 24, 2024

COVID-19 pandemic has had a substantial effect on healthcare systems worldwide, including the care of patients with lung cancer. The impact disruptions and behavioral changes cancer mortality is unclear. Patients newly diagnosed during period 2020-2021 were compared those in pre-pandemic 2018-2019. primary outcome was all-cause within 1 year. Cox proportional hazards regression analyses conducted to estimate between pre-pandemic. Multiple mediation performed determine factors that accounted for mortality. In total, 5785 included this study. overall rate significantly higher (crude hazard ratio [HR]: 1.19, 95% confidence interval [CI]: 1.05, 1.29). Mediation showed not receiving tumor-directed treatment, diagnosis at an older age, decreased through screening 17.5% (95%CI: 4.2, 30.7), 13.9% 0.8, 27.0), 12.4% 3.0, 21.8) increased mortality, respectively. This study revealed significant increase risk who have received treatment or screening, despite potential selection bias follow-up status. Efforts should be focused ensuring timely access services, optimizing delivery, addressing unique challenges faced by mitigate outcomes provide clinical vulnerable populations.

Language: Английский

Citations

0