Alimentary Pharmacology & Therapeutics, Journal Year: 2024, Volume and Issue: 59(4), P. 585 - 586
Published: Jan. 21, 2024
LINKED CONTENT This article is linked to Thomson et al papers. To view these articles, visit https://doi.org/10.1111/apt.17823 and https://doi.org/10.1111/apt.17842
Language: Английский
MMWR Morbidity and Mortality Weekly Report, Journal Year: 2024, Volume and Issue: 73(8), P. 154 - 161
Published: Feb. 29, 2024
Deaths from causes fully attributable to alcohol use have increased during the past 2 decades in United States, particularly 2019 2020, concurrent with onset of COVID-19 pandemic.However, previous studies trends not assessed underlying deaths that are partially use, such as injuries or certain types cancer.CDC's Alcohol-Related Disease Impact application was used estimate average annual number and agestandardized rate excessive States based on 58 alcohol-related death three periods (2016-2017, 2018-2019, 2020-2021).Average 29.3%, 137,927 2016-2017 178,307 2020-2021; age-standardized rates 38.1 47.6 per 100,000 population.During this time, among males 26.8%, 94,362 year 119,606, females 34.7%, 43,565 58,701.Implementation evidence-based policies reduce availability accessibility increase its price (e.g., concentration places selling taxes) could deaths.* https://www.cdc.gov/nchs/products/databriefs/db448.htmalcohol sales † also time.Previous included (1,3), cancer, for which drinking is a substantial risk factor (4,5).A comprehensive assessment changes includes conditions can guide rationale implementation effective prevention strategies. Methods
Language: Английский
Citations
61
Annals of Internal Medicine, Journal Year: 2024, Volume and Issue: 177(5), P. 656 - 657
Published: April 22, 2024
Alcohol is used by more people in the United States than tobacco, electronic nicotine delivery systems, or illicit drugs. Several health conditions, including cancer, cardiovascular disease, and liver are associated with excessive alcohol use disorder. Nearly 30 million aged 12 years older reported past-year disorder 2022, but-despite its prevalence-alcohol undertreated. In this policy brief, American College of Physicians outlines effects disorder, calls for changes to increase availability treatment use, recommends alcohol-related public interventions.
Language: Английский
Citations
6
JAMA Health Forum, Journal Year: 2024, Volume and Issue: 5(4), P. e240501 - e240501
Published: April 12, 2024
Importance Research has demonstrated an association between the COVID-19 pandemic and increased alcohol-related liver disease hospitalizations deaths. However, trends in complications more broadly are unclear, especially among subgroups disproportionately affected by alcohol use. Objective To assess people with high-acuity admitted to emergency department, observation unit, or hospital during pandemic, focusing on demographic differences. Design, Setting, Participants This longitudinal interrupted time series cohort study analyzed US national insurance claims data using Optum’s deidentified Clinformatics Data Mart database from March 2017 September 2021, before after 2020 onset. A rolling of 15 years older who had at least 6 months continuous commercial Medicare Advantage coverage were included. Subgroups interest included males females stratified age group. April 2023 January 2024. Exposure environment 2021. Main Outcomes Measures Differences monthly rates vs predicted complication episodes, determined claims-based algorithms alcohol-specific diagnosis codes. The secondary outcome was subset episodes due disease. Results Rates statistically higher than expected 4 18 (range absolute relative increases: 0.4-0.8 per 100 000 8.3%-19.4%, respectively). Women aged 40 64 experienced significant increases 10 1.3-2.1 33.3%-56.0%, In this same population, above 16 0.8-2.1 34.1%-94.7%, Conclusions Relevance a national, commercially insured beyond what months. 33.3% 56.0% months, pattern associated large sustained complications. Findings underscore need for attention use disorder risk factors, patterns, health effects, regulations policies, women years.
Language: Английский
Citations
5
Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)
Published: Feb. 1, 2024
In recent years, there has been a global trend of aging, which resulted in significant changes to the burden gastritis and duodenitis (GD). Using disease (GBD) database spanning 1990 2019, we evaluated temporal trends age-standardized incidence rates (ASIR), death (ASDR), disability-adjusted life years (AS-DALYs) for GD using estimated annual percentage (EAPC). Additionally, examined across various strata, including social demographic index (SDI), age, sex. Finally, risk factors linked mortality GD, utilizing Pearson correlation analysis. were 31 million patients globally, notable increase 12 from 1990, while ASIR, ASDR, AS-DALYs all showed decrease. Correlation analysis negative relationship between ASIR SDI. Factors like hand hygiene vitamin A deficiency had positive correlations with ASDR 2019. Over past thirty increased alongside population aging. Future efforts should focus on exploring prevention special attention elderly low SDI regions.
Language: Английский
Citations
4
Journal of Korean Medical Science, Journal Year: 2024, Volume and Issue: 39(46)
Published: Jan. 1, 2024
Liver disease causes over two million deaths annually worldwide, comprising approximately 4% of all global fatalities. We aimed to analyze liver disease-related mortality trends from 1990 2021 using the World Health Organization (WHO) Mortality Database and forecast rates up 2050.
Language: Английский
Citations
4
NPP—Digital Psychiatry and Neuroscience, Journal Year: 2025, Volume and Issue: 3(1)
Published: Jan. 3, 2025
Abstract Reinforcement learning studies propose that decision-making is guided by a tradeoff between computationally cheaper model-free (habitual) control and costly model-based (goal-directed) control. Greater typically used under highly rewarding conditions to minimize risk maximize gain. Although prior have shown impairments in sensitivity reward value individuals with frequent alcohol use, it unclear how these arbitrate based on the magnitude of incentives. In this study, 81 (47 Alcohol Users 34 Non-Users) performed modified 2-step task where stakes were sometimes high, other times they low. Maximum posteriori fitting dual-system reinforcement-learning model was assess degree control, utility for low- high-stakes trials separately. As expected, Non-Users showed significantly higher compared lower conditions, whereas no such difference two observed Users. Additionally, both groups less risk-averse conditions. However, condition. Lastly, greater associated risk-sensitive approach Taken together, results suggest may impaired metacontrol, making them flexible varying monetary rewards more prone risky decision-making, especially when are high.
Language: Английский
Citations
0
American Journal of Preventive Cardiology, Journal Year: 2025, Volume and Issue: 21, P. 100947 - 100947
Published: Feb. 8, 2025
To examine the associations between unhealthy alcohol use and risk of coronary heart disease (CHD) among women men aged 18-65 years. An observational study in an integrated healthcare system with systematic screening. We identified 432,265 primary care patients years who, 2014-2015, reported weekly intake levels. Weekly intake, categorized into below (≤14/week men; ≤7/week women) above limits (≥15/week ≥ 8/week per U.S. guidelines, heavy episodic drinking (HED, ≥5/≥4 drinks any day past 3 months for men/women, respectively). Main outcome was CHD during 4-year follow-up, based on inpatient ICD diagnoses myocardial infarction CHD. Cox proportional hazards models adjusted age, sex, race/ethnicity, body mass index, physical activity, smoking, hypertension, diabetes, hyperlipidemia. The cohort comprised 44 % women, mean age (standard deviation) 43.5 (±13.1). associated higher prevalence cardiovascular factors, a 26 %, 19 43 overall, men- women-specific after adjusting these factors (hazard ratio [95 confidence interval] = 1.26[1.13 -1.40], 1.19[1.04-1.35] 1.43[1.20-1.71], In large, real-world, diverse population screening program, having increased young middle-aged women. Increased due to warrants particular awareness interventions.
Language: Английский
Citations
0
Nursing for Women s Health, Journal Year: 2025, Volume and Issue: unknown
Published: March 1, 2025
Language: Английский
Citations
0
JAMA Network Open, Journal Year: 2025, Volume and Issue: 8(3), P. e250695 - e250695
Published: March 13, 2025
Importance Evidence-based, patient-centered treatment for alcohol use disorder (AUD) can include pharmacotherapy with naltrexone, acamprosate, or disulfiram; however, these medications are rarely used. Medicaid managed care plans (MCPs) manage health services nearly 80% of enrollees and the largest payer addiction services. Little is known about MCP policies AUD medications. Objectives To describe MCPs’ coverage management disulfiram examine associations plan characteristics state medication coverage. Design, Setting, Participants In this cross-sectional study, a content analysis was performed 2021 insurance benefit data 241 comprehensive MCPs in states using care, as well secondary sources. Data were analyzed from May to August 2024. Main Outcomes Measures MCP-reported utilization requirements (eg, prior authorization, quantity limit requirements) disulfiram, oral injectable naltrexone together each separately. Independent variables included (profit status, market share) policy environment which embedded (Section 1115 substance waiver, state-defined preferred drug list). Regressions examined Results 2021, 217 (90.0%) covered at least 1 AUD: 132 (54.7%) 203 (84.2%) 175 (72.6%) 152 (63.0%) 103 (42.7%) all 4 Prior authorization limits applied, except 75 (42.8%) imposed requirements. Conclusions Relevance This study suggests that efforts expand prescribing may be limited by gaps support covering without applying strategies.
Language: Английский
Citations
0
Current Addiction Reports, Journal Year: 2025, Volume and Issue: 12(1)
Published: March 22, 2025
Language: Английский
Citations
0