Prevalence of Cardiovascular-Kidney-Metabolic Stages in US Adolescents and Relationship to Social Determinants of Health DOI Creative Commons
Carissa M. Baker‐Smith, Abigail M. Gauen, Lucia C. Petito

et al.

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 27, 2024

Abstract Importance Given that many risk factors for atherosclerotic cardiovascular disease (ASCVD) begin in childhood, knowledge of the prevalence cardio-kidney metabolic syndrome (CKM) adolescents and its is critical to understanding etiology ASCVD burden. Objective To calculate proportion US with CKM stages 0, 1, 2 assess social behaviors most strongly associated advanced stage. Design Cross-sectional analysis 2017-2020 National Health Nutrition Examination Survey (NHANES) sample data. Setting United States Participants Adolescents Exposure Social determinants health, including family income poverty ratio, health insurance, routine healthcare access, food security, as well smoking, physical activity, diet. Main Outcomes Measures The was measured using survey-weighted Generalized linear models were used quantify associations between factors, behaviors, staging. Results Of 1,774 surveyed ages 12-18 years, representing 30,327,145 adolescents, 56% (95% CI 52-60%) had stage 37% (33-40%) 7% (5-9%) 2. Physical activity score (1 100, 100=highest) lowest among (physical 0: 60 (31), 1: (32), 49 (33); p=0.025). Other such DASH diet nicotine scores, did not differ according (p=0.477 p=0.932, respectively). According sex, race, ethnicity, age-adjusted multivariate logistic regression analyses, a ratio level >1.85, having 32% (OR 0.68 [95% CI:0.52,0.89]), 40% 0.60 CI: 0.37, 0.99]), 45% 0.55 0.41,0.73]) lower odds 1-2, respectively. After adjustment all sociodemographic only security 41% 1-2 0.59 [0.43, 0.81]). Conclusions Relevance insecurity. Improved access healthy policies address may help prevent higher stage, beginning adolescence. Clinical Perspective Key Points Question : What what are 0,1, adolescents? Findings In this population-based study, 44% 1 2, presence household security. Meaning By addressing US, we improve across lifespan.

Language: Английский

From childhood cancer to metabolic syndrome DOI Open Access
Aman Wadhwa

Cancer, Journal Year: 2025, Volume and Issue: 131(1)

Published: Jan. 1, 2025

The prevalence of metabolic syndrome among adult survivors childhood cancer is higher compared to a noncancer control population. Therapeutic exposures and lifestyle factors are associated with the risk syndrome.

Language: Английский

Citations

0
Exposomic Determinants of Atherosclerosis: Recent Evidence DOI
Omar Hahad, Usman Sagheer,

Khurram Nasir

et al.

Current Atherosclerosis Reports, Journal Year: 2025, Volume and Issue: 27(1)

Published: Jan. 22, 2025

Language: Английский

Citations

0
Associations of cardiovascular–kidney–metabolic syndrome stages with premature mortality and the role of social determinants of health DOI Creative Commons
Ruixin Zhu, Ran Wang, Jingjing He

et al.

The journal of nutrition health & aging, Journal Year: 2025, Volume and Issue: 29(4), P. 100504 - 100504

Published: Feb. 13, 2025

Language: Английский

Citations

0
Etiology, Pathophysiology, and Treatment Strategies in the Prevention and Management of Metabolic Syndrome DOI Open Access
Ritika Patial,

Irene Batta,

Manish Thakur

et al.

Archives of Internal Medicine Research, Journal Year: 2024, Volume and Issue: 7(4)

Published: Jan. 1, 2024

Metabolic Syndrome (MetS) is a complex cluster of metabolic irregularities that significantly increase the risk developing chronic conditions, such as hypertension, type 2 diabetes, cardiovascular diseases, and other related disorders. This review aims to provide comprehensive overview current understanding MetS, its etiology underlying pathogenesis, management strategies. MetS characterized by central obesity, high blood pressure, insulin resistance, hyperglycemia, hypertriglyceridemia, low high-density lipoprotein cholesterol levels. The prevalence remarkably high, affecting approximately 25% global population, particularly in developed nations with inactive lifestyles high-calorie diets. development involves genetic acquired factors, resulting an inflammatory state enhances for disease. biochemical alterations observed establish pathological connections between neurodegenerative conditions. Despite clinical importance, there still debate regarding precise components pathophysiological associations among elements. However, advancements therapeutic measures, including drug therapies, surgical options, experimental methods present promising avenues managing potentially reversing MetS. Further investigation critical because significant implications public health connection conditions severe outcomes, placing substantial burden on healthcare system society.

Language: Английский

Citations

1
Prevalence of Cardiovascular-Kidney-Metabolic Stages in US Adolescents and Relationship to Social Determinants of Health DOI Creative Commons
Carissa M. Baker‐Smith, Abigail M. Gauen, Lucia C. Petito

et al.

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 27, 2024

Abstract Importance Given that many risk factors for atherosclerotic cardiovascular disease (ASCVD) begin in childhood, knowledge of the prevalence cardio-kidney metabolic syndrome (CKM) adolescents and its is critical to understanding etiology ASCVD burden. Objective To calculate proportion US with CKM stages 0, 1, 2 assess social behaviors most strongly associated advanced stage. Design Cross-sectional analysis 2017-2020 National Health Nutrition Examination Survey (NHANES) sample data. Setting United States Participants Adolescents Exposure Social determinants health, including family income poverty ratio, health insurance, routine healthcare access, food security, as well smoking, physical activity, diet. Main Outcomes Measures The was measured using survey-weighted Generalized linear models were used quantify associations between factors, behaviors, staging. Results Of 1,774 surveyed ages 12-18 years, representing 30,327,145 adolescents, 56% (95% CI 52-60%) had stage 37% (33-40%) 7% (5-9%) 2. Physical activity score (1 100, 100=highest) lowest among (physical 0: 60 (31), 1: (32), 49 (33); p=0.025). Other such DASH diet nicotine scores, did not differ according (p=0.477 p=0.932, respectively). According sex, race, ethnicity, age-adjusted multivariate logistic regression analyses, a ratio level >1.85, having 32% (OR 0.68 [95% CI:0.52,0.89]), 40% 0.60 CI: 0.37, 0.99]), 45% 0.55 0.41,0.73]) lower odds 1-2, respectively. After adjustment all sociodemographic only security 41% 1-2 0.59 [0.43, 0.81]). Conclusions Relevance insecurity. Improved access healthy policies address may help prevent higher stage, beginning adolescence. Clinical Perspective Key Points Question : What what are 0,1, adolescents? Findings In this population-based study, 44% 1 2, presence household security. Meaning By addressing US, we improve across lifespan.

Language: Английский

Citations

0