Smart Hydrogels for Bone Reconstruction via Modulating the Microenvironment DOI Creative Commons

Weikai Chen,

Hao Zhang,

Qirong Zhou

et al.

Research, Journal Year: 2023, Volume and Issue: 6

Published: Jan. 1, 2023

Rapid and effective repair of injured or diseased bone defects remains a major challenge due to shortages implants. Smart hydrogels that respond internal external stimuli achieve therapeutic actions in spatially temporally controlled manner have recently attracted much attention for therapy regeneration. These can be modified by introducing responsive moieties embedding nanoparticles increase their capacity repair. Under specific stimuli, smart variable, programmable, controllable changes on demand modulate the microenvironment promoting healing. In this review, we highlight advantages summarize materials, gelation methods, properties. Then, overview recent advances developing biochemical signals, electromagnetic energy, physical including single, dual, multiple types enable physiological pathological modulating microenvironment. discuss current challenges future perspectives regarding clinical translation hydrogels.

Language: Английский

Mechanically robust and conductive poly(acrylamide) nanocomposite hydrogel by the synergistic effect of vinyl hybrid silica nanoparticle and polypyrrole for human motion sensing DOI
Kaichang Cheng,

Lin Zou,

Baobao Chang

et al.

Advanced Composites and Hybrid Materials, Journal Year: 2022, Volume and Issue: 5(4), P. 2834 - 2846

Published: May 5, 2022

Language: Английский

Citations

72
Stimuli-responsive dynamic hydrogels: design, properties and tissue engineering applications DOI
Sivashanmugam Amirthalingam, Arun Rajendran,

Young Gi Moon

et al.

Materials Horizons, Journal Year: 2023, Volume and Issue: 10(9), P. 3325 - 3350

Published: Jan. 1, 2023

This review provides a brief overview of the recent developments in hydrogel systems that respond dynamically to various stimuli, including some interesting fabrication strategies, and their application cardiac, bone, neural tissue regeneration.

Language: Английский

Citations

70
Advanced stimuli-responsive membranes for smart separation DOI
Tiefan Huang,

Zhixin Su,

Kun Hou

et al.

Chemical Society Reviews, Journal Year: 2023, Volume and Issue: 52(13), P. 4173 - 4207

Published: Jan. 1, 2023

This review summarises the advancements of stimuli-responsive membranes, focusing on chemistry, controllable membrane properties, preparation, and advanced applications.

Language: Английский

Citations

62
Designing self-healing hydrogels for biomedical applications DOI
Xiaoya Ding, Lu Fan, Li Wang

et al.

Materials Horizons, Journal Year: 2023, Volume and Issue: 10(10), P. 3929 - 3947

Published: Jan. 1, 2023

Self-healing hydrogels based on various dynamic interactions are comprehensively summarized and their biomedical applications also thoroughly elaborated.

Language: Английский

Citations

61
Smart Hydrogels for Bone Reconstruction via Modulating the Microenvironment DOI Creative Commons

Weikai Chen,

Hao Zhang,

Qirong Zhou

et al.

Research, Journal Year: 2023, Volume and Issue: 6

Published: Jan. 1, 2023

Rapid and effective repair of injured or diseased bone defects remains a major challenge due to shortages implants. Smart hydrogels that respond internal external stimuli achieve therapeutic actions in spatially temporally controlled manner have recently attracted much attention for therapy regeneration. These can be modified by introducing responsive moieties embedding nanoparticles increase their capacity repair. Under specific stimuli, smart variable, programmable, controllable changes on demand modulate the microenvironment promoting healing. In this review, we highlight advantages summarize materials, gelation methods, properties. Then, overview recent advances developing biochemical signals, electromagnetic energy, physical including single, dual, multiple types enable physiological pathological modulating microenvironment. discuss current challenges future perspectives regarding clinical translation hydrogels.

Language: Английский

Citations

58