MedComm,
Journal Year:
2024,
Volume and Issue:
5(8)
Published: July 20, 2024
Abstract
Nanomaterials
have
aroused
great
interests
in
drug
delivery
due
to
their
nanoscale
structure,
facile
modifiability,
and
multifunctional
physicochemical
properties.
Currently,
stimuli‐responsive
nanomaterials
that
can
respond
endogenous
or
exogenous
stimulus
display
strong
potentials
biomedical
applications.
In
comparison
with
conventional
nanomaterials,
improve
therapeutic
efficiency
reduce
the
toxicity
of
drugs
toward
normal
tissues
through
specific
targeting
on‐demand
release
at
pathological
sites.
this
review,
we
summarize
responsive
mechanism
a
variety
stimulus,
including
pH,
redox,
enzymes
within
microenvironment,
as
well
such
thermal
effect,
magnetic
field,
light,
ultrasound.
After
that,
applications
(e.g.,
delivery,
imaging,
theranostics)
diverse
array
common
diseases,
cardiovascular
cancer,
neurological
disorders,
inflammation,
bacterial
infection,
are
presented
discussed.
Finally,
remaining
challenges
outlooks
future
research
directions
for
also
We
hope
review
provide
valuable
guidance
developing
accelerate
diseases
diagnosis
treatment.
Small,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 8, 2025
Abstract
In
recent
years,
nanomaterials
have
demonstrated
broad
prospects
in
the
diagnosis
and
treatment
of
retinal
diseases
due
to
their
unique
physicochemical
properties,
such
as
small‐size
effects,
high
biocompatibility,
functional
surfaces.
Retinal
are
often
accompanied
by
complex
pathological
microenvironments,
where
conventional
diagnostic
therapeutic
approaches
face
challenges
low
drug
delivery
efficiency,
risks
associated
with
invasive
procedures,
difficulties
real‐time
monitoring.
Nanomaterials
hold
promise
addressing
these
limitations
traditional
therapies,
thereby
improving
precision
efficacy.
The
applications
diagnostics
summarized,
they
enable
high‐resolution
imaging
carrying
fluorescent
probes
or
contrast
agents
act
biosensors
sensitively
detect
disease‐related
biomarkers,
facilitating
early
dynamic
therapeutics,
functionalized
nanocarriers
can
precisely
deliver
drugs,
genes,
antioxidant
molecules
target
cells,
significantly
enhancing
outcomes
while
reducing
systemic
toxicity.
Additionally,
nanofiber
materials
possess
properties
that
make
them
particularly
suitable
for
regeneration
tissue
engineering.
By
loading
neurotrophic
factors
into
scaffolds,
regenerative
effects
be
amplified,
promoting
repair
neurons.
Despite
immense
potential,
clinical
translation
still
requires
long‐term
biosafety,
scalable
manufacturing
processes,
optimization
targeting
efficiency.
Sensors International,
Journal Year:
2024,
Volume and Issue:
5, P. 100293 - 100293
Published: Jan. 1, 2024
Graphene
and
its
derivatives
have
become
essential
materials
in
modern
biomedical
research
due
to
their
positive
impact
on
various
applications.
Moreover,
the
integration
of
graphene-based
with
microfluidics
technology
has
opened
up
new
possibilities.
The
novelty
current
review
is
considering
comprehensive
analysis
transformative
graphene
applications,
particularly
highlighting
technology.
While
many
studies
focused
individual
applications
graphene,
this
uniquely
present
a
holistic
view
potential
across
fields,
including
drug
delivery,
gene
tissue
engineering,
photothermal
treatment,
detection,
sensor
respect
conventional
techniques.
In
review,
we
analysed
published
unveil
increasing
interest
graphene's
healthcare
medicine,
as
well
prospects
for
further
exploration.
We
explore
fundamental
concepts
properties,
latest
medical
implants
biological
fields
within
context
prospects.
also
addresses
challenges
limitations
these
promising
future,
recognizing
that
still
early
stages
compared
commercial
MedComm,
Journal Year:
2024,
Volume and Issue:
5(8)
Published: July 20, 2024
Abstract
Nanomaterials
have
aroused
great
interests
in
drug
delivery
due
to
their
nanoscale
structure,
facile
modifiability,
and
multifunctional
physicochemical
properties.
Currently,
stimuli‐responsive
nanomaterials
that
can
respond
endogenous
or
exogenous
stimulus
display
strong
potentials
biomedical
applications.
In
comparison
with
conventional
nanomaterials,
improve
therapeutic
efficiency
reduce
the
toxicity
of
drugs
toward
normal
tissues
through
specific
targeting
on‐demand
release
at
pathological
sites.
this
review,
we
summarize
responsive
mechanism
a
variety
stimulus,
including
pH,
redox,
enzymes
within
microenvironment,
as
well
such
thermal
effect,
magnetic
field,
light,
ultrasound.
After
that,
applications
(e.g.,
delivery,
imaging,
theranostics)
diverse
array
common
diseases,
cardiovascular
cancer,
neurological
disorders,
inflammation,
bacterial
infection,
are
presented
discussed.
Finally,
remaining
challenges
outlooks
future
research
directions
for
also
We
hope
review
provide
valuable
guidance
developing
accelerate
diseases
diagnosis
treatment.
