Selenium-Doped Copper Formate Nanozymes with Antisenescence and Oxidative Stress Reduction for Atherosclerosis Treatment DOI

Xiao Huang,

Yue Zhou, Yun Guo

et al.

Nano Letters, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 17, 2025

Atherosclerosis, resulting from chronic inflammation of the arterial wall, serves as underlying cause multiple major cardiovascular diseases. Current anti-inflammatory therapies often exhibit limited and unsatisfactory efficacy. To address this, we have designed a selenium-doped copper formate (Cuf-Se) nanozyme for treatment atherosclerosis, which possesses superoxide dismutase (SOD) glutathione peroxidase (GPx)-like activities. The Cuf-Se can efficiently scavenge reactive oxygen species (ROS), inhibit cellular senescence, prevent formation foam cells. It acts on macrophages to reduce ROS levels lipid oxidation, thereby significantly inhibiting inflammation-related processes. Notably, while cell formation, also alleviates endothelial cells senescence. After intravenous administration, effectively inhibits atherosclerosis in mice through synergistic effects antisenescence antioxidant properties, reducing plaque area by approximately 5-fold. This study provides an effective strategy atherosclerosis.

Language: Английский

Advances and challenges in the electrochemical reduction of carbon dioxide DOI Creative Commons

Jingyi Han,

Xue Bai,

Xiaoqin Xu

et al.

Chemical Science, Journal Year: 2024, Volume and Issue: 15(21), P. 7870 - 7907

Published: Jan. 1, 2024

This review highlights the structure–activity relationship of ECO 2 RR, provides a detailed summary advanced materials by analyzing electrocatalytic applications and reaction mechanisms, discusses challenges in both devices.

Language: Английский

Citations

48
Asymmetric active sites originate from high-entropy metal selenides by joule heating to boost electrocatalytic water oxidation DOI
Fangren Qian, Lishan Peng,

Dengfeng Cao

et al.

Joule, Journal Year: 2024, Volume and Issue: 8(8), P. 2342 - 2356

Published: June 25, 2024

Language: Английский

Citations

25
Urea Synthesis via Coelectrolysis of CO2 and Nitrate over Heterostructured Cu–Bi Catalysts DOI
Xinning Song, Xiaodong Ma, Tianhui Chen

et al.

Journal of the American Chemical Society, Journal Year: 2024, Volume and Issue: 146(37), P. 25813 - 25823

Published: Sept. 5, 2024

Electrocatalytic coupling of CO

Language: Английский

Citations

16
A molecular view of single-atom catalysis toward carbon dioxide conversion DOI Creative Commons
Xin Shang,

Xiaofeng Yang,

Ye Liu

et al.

Chemical Science, Journal Year: 2024, Volume and Issue: 15(13), P. 4631 - 4708

Published: Jan. 1, 2024

We present critical advances in single-atom catalysis toward CO 2 transformation and address crucial issues about SACs from a molecular point of view.

Language: Английский

Citations

14
Linkage Engineering in Covalent Organic Frameworks for Metal‐Free Electrocatalytic C2H4 Production from CO2 DOI
Xiao Yang, Jie Lu,

Kean Chen

et al.

Angewandte Chemie International Edition, Journal Year: 2024, Volume and Issue: 63(26)

Published: April 18, 2024

Electrocatalytic carbon dioxide reduction reaction (CO

Language: Английский

Citations

14
Cu–Mo Dual Sites in Cu-Doped MoSe2 for Enhanced Electrosynthesis of Urea DOI

Jiadi Jiang,

Guanzheng Wu,

Mengmiao Sun

et al.

ACS Nano, Journal Year: 2024, Volume and Issue: 18(21), P. 13745 - 13754

Published: May 13, 2024

The quest for sustainable urea production has directed attention toward electrocatalytic methods that bypass the energy-intensive traditional Haber–Bosch process. This study introduces an approach to synthesis through coreduction of CO2 and NO3– using copper-doped molybdenum diselenide (Cu–MoSe2) with Cu–Mo dual sites as electrocatalysts. activity Cu–MoSe2 electrode is characterized by a yield rate 1235 μg h–1 mgcat.–1 at −0.7 V versus reversible hydrogen maximum Faradaic efficiency 23.43% −0.6 RHE. Besides, continuous enhanced average 9145 can be achieved in flow cell. These figures represent substantial advancement over baseline MoSe2 electrode. Density functional theory (DFT) calculations elucidate Cu doping accelerates *NO2 deoxygenation significantly decreases energy barriers C–N bond formation. Consequently, demonstrates more favorable pathway production, enhancing both feasibility offers valuable insights into design understanding facilitated electrochemical pathways.

Language: Английский

Citations

13
Modulating the localized electronic distribution of Cu species during reconstruction for enhanced electrochemical CO2 reduction to C2+ products DOI

Zongmiao Li,

Zhu Liu, Shiju Li

et al.

Journal of Materials Chemistry A, Journal Year: 2024, Volume and Issue: 12(25), P. 15082 - 15089

Published: Jan. 1, 2024

ZrO 2 stabilized Cu + can optimize *CO adsorption and promote the following C–C coupling to achieve 70+% FE C 2+ in a wide potential range.

Language: Английский

Citations

12
Unveiling the Mechanism of Plasma-Catalyzed Oxidation of Methane to C2+ Oxygenates over Cu/UiO-66-NH2 DOI Creative Commons
Chong Qi,

Yifu Bi,

Yaolin Wang

et al.

ACS Catalysis, Journal Year: 2024, Volume and Issue: 14(10), P. 7707 - 7716

Published: May 2, 2024

Nonthermal plasma (NTP) offers the potential for converting CH4 with CO2 into liquid products under mild conditions, but controlling selectivity and manipulating intermediate species remain significant challenges. Here, we demonstrate effectiveness of Cu/UiO-66-NH2 catalyst in promising conversion oxygenates within a dielectric barrier discharge NTP reactor ambient conditions. The 10% achieved an impressive 53.4% overall selectivity, C2+ accounting ∼60.8% total products. In situ plasma-coupled Fourier-transform infrared spectroscopy (FTIR) suggests that Cu facilitates cleavage surface adsorbed COOH (*COOH), generating *CO enabling its migration to particles. This surface-bound then undergoes C–C coupling hydrogenation, leading ethanol production. Further analysis using CO diffuse reflection FTIR 1H nuclear magnetic resonance indicates generated is more effective than gas-phase (g) promoting formation. work provides valuable mechanistic insights production during plasma-catalytic oxidation These findings hold broader implications rational design efficient catalysts this reaction, paving way advancements sustainable fuel chemical

Language: Английский

Citations

11
Hydration‐effect Boosted Active Hydrogen Facilitates Neutral Ammonia Electrosynthesis from Nitrate Reduction DOI
Meng Zhang,

Xuetao Cheng,

Yun Duan

et al.

Advanced Functional Materials, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 8, 2024

Abstract Electrocatalytic nitrate reduction to ammonia (NO 3 RR) in a neutral medium is green and effective strategy for treating pollution meanwhile producing ammonia. However, the insufficient active hydrogen (H * ) on catalyst surface resulting from sluggish Volmer step 2 O → H + OH − ), competitive evolution reaction (HER) caused by coupling severely restrict enhancement of NO RR activity. Herein, hydration‐effect boosted ‐rich facilitating electrosynthesis proposed. The introduction hydration‐effect‐promoting element aluminum into copper‐based forming CuAlO , which adjusts electron density distribution system, significantly promotes generation medium. Moreover, rapid charge transfer at CuO/CuAlO interface facilitates kinetics diffusion. More importantly, Al weakens overly strong adsorption intermediates CuO, thereby accelerating hydrogenation process suppressing HER. Thus, under conditions, reached Faradaic efficiency an yield as high 97.81 ± 1.94% 10.21 0.64 mg h −1 cm −2 −1.0 V versus RHE toward RR.

Language: Английский

Citations

10
Operando Reconstruction of Porous Carbon Supported Copper Selenide Promotes the C2 Production from CO2RR DOI
Simeng Li, Jun Yu, Shengsen Zhang

et al.

Advanced Functional Materials, Journal Year: 2023, Volume and Issue: 34(12)

Published: Dec. 15, 2023

Abstract Precisely regulating surface reconstruction of copper (Cu) chalcogenides‐based catalysts to promote the multicarbon (C 2+ )selectivity electrochemical CO 2 reduction reaction (CO RR) is hampered by challenging control intractable anions and optimal Cu δ+ (0 < δ 1). Herein, a porous carbon‐supported selenides electrocatalyst that can remarkably improve C ‐product yield especially unveil time‐revolved RR process enable high ‐selectivity, most notably for ethanol constructed. The Faradic efficiency (FE) ‐products achieved as ≈85.2% with partial current density 229.5 mA cm −2 . Operando infrared spectroscopy functional theory (DFT) calculations unravel Se vacancies ( V ) formation brings closer neighboring + atoms activates sites, thereby rendering efficient generation key intermediates * CHO) lowering C–C coupling barrier production. appearance metallic shorten next‐nearest 0 –Cu distance O atom bridge in, leading preferential OC H 4 towards instead C–O bond cleavage form ethylene. This work opens avenue designing suitable local atomic structures engage targeted products.

Language: Английский

Citations

22