Biomaterials, Journal Year: 2024, Volume and Issue: 316, P. 123036 - 123036
Published: Dec. 19, 2024
Language: Английский
Advanced Functional Materials, Journal Year: 2024, Volume and Issue: unknown
Published: Nov. 26, 2024
Abstract Electrospinning is a significant manufacturing strategy to create micro/nanofiber platforms that can be considered biomedical scaffold for tissue engineering repair and regeneration. In recent years researchers have continuously broadened the equipment design materials development of electrospinning nanofiber (ENPs), which evolved from single‐needle multi‐needle creating 3D ENPs, diversify their application including drugs/cell/growth factors release, anti‐bacterial anti‐inflammatory, hemostasis, wound healing, Herein, multifunctional ENPs with bioactive polymer fabricated via in terms novel material design, construction various structures, requirements different regeneration are reviewed. Furthermore, this review delves into advancements facilitated by highlighting effectiveness versatility across types such as bone, cartilage, tendons, cardiac tissue, nerves. The discussion comprehensively addresses ongoing challenges selection, biodegradation mechanisms, bioactivation strategies, techniques specific applications. Moreover, outlines potential future research avenues aimed at enhancing ENPs‐based approaches engineering. This in‐depth analysis aims provide nuanced insights technical recommendations propel field forward
Language: Английский
Citations
11
Advanced Healthcare Materials, Journal Year: 2024, Volume and Issue: 13(27)
Published: July 7, 2024
Abstract The limited and unstable absorption of excess exudate is a major challenge during the healing infected wounds. In this study, highly stable, multifunctional Janus dressing with unidirectional transfer capacity fabricated based on single poly(lactide caprolactone) (PLCL). success method relies an acid hydrolysis reaction that transforms PLCL fibers from hydrophobic to hydrophilic in situ. resulting interfacial affinity between hydrophilic/phobic endows structure excellent liquid high structural stability against repeated stretching, bending, twisting. Various other functions, including wound status detection, antibacterial, antioxidant, anti‐inflammatory properties, are also integrated into by incorporating phenol red epigallocatechin gallate. An vivo methicillin‐resistant Staphylococcus aureus ‐infected model confirms dressing, capability remove site, not only facilitates epithelialization collagen deposition, but ensures low inflammation angiogenesis, thus reaching ideal closure rate up 98.4% day 14. simple structure, multiple easy fabrication may offer promising strategy for treating chronic wounds, rooted challenges bacterial infection, excessive exudate, persistent inflammation.
Language: Английский
Citations
9
ACS Applied Materials & Interfaces, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 20, 2025
Long-term inflammation and persistent bacterial infection are primary contributors to unhealed chronic wounds. The use of conventional antibiotics often leads bacteria drug resistance, diminishing wound healing effectiveness. Nanozymes have become a promising alternative antimicrobial materials due their low cost, easy synthesis, good stability. Herein, we develop novel sprayable hydrogel based on carboxymethyl chitosan (CMCS) oxidized hyaluronic acid (OHA), incorporating Au nanoparticle-carbon nitride (AuNPs-C3N4) nanozyme, glucose, Mn2+ for bacteria-infected healing. forms rapidly in situ upon spraying gradually degrades the area, releasing AuNPs-C3N4 which exhibits robust glucose oxidase-like (GOx-like) activity, initiating comprehensive catalytic cascade through Mn2+-mediated Fenton-like reaction that generates hydroxyl radicals (•OH) eliminate Staphylococcus aureus (S. aureus) Methicillin-resistant S. (MRSA). Computational results indicate interactions between AuNPs g-C3N4 maximize synergistic effects heterojunction, improving O2 adsorption facilitating electron-O2 optimize activity. Further experiments demonstrate can cover wounds situ, while CMCS promotes collagen production fibroblast proliferation, offering viable strategy
Language: Английский
Citations
1
Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 160235 - 160235
Published: Feb. 1, 2025
Language: Английский
Citations
1
ACS Nano, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 6, 2025
Directional liquid transport fibrous matrices (DLTFMs) have the unique ability to direct movement in a single direction through their thickness. Beyond inherent function, DLTFMs can also enhance effectiveness of additional functionalities. This review focuses on recent advances DLTFMs, particularly role DLTs enhancing secondary functions. We begin with brief overview historical development and major achievements DLTFM research, followed by an outline classification, fabrication techniques, basic functions derived from natural properties. The integration DLT functionalities such as responsiveness, thermal regulation, wearable technology for innovative applications various sectors is then discussed. concludes discussion key challenges prospects field, including durability reliability performance, precise regulation fluid rates, resilience longevity harsh environments, impact variations performance enhancement. goal this stimulate further studies promote practical implementation variety industries.
Language: Английский
Citations
1
ACS Nano, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 13, 2025
Adaptive surfaces with tunable wettability have attracted considerable attention due to their increasing importance in adapting real applications. By incorporation of stimuli-sensitive materials that enable control over surface chemistry or topographical features, both, a variety adaptive are engineered exhibit reversible tailoring wettability. This Review provides comprehensive review the development stimuli-responsive It begins by outlining background and significance surfaces. Then, this delves into fundamental theories govern wettability, focusing on influence external stimuli wetting behavior. The discussion then shifts highlighting various triggers, such as magnetism, photo, temperature, pH, electricity, gas stimuli, drive response well respond dual multiple stimuli. further explores primary leading applications droplet manipulation, oil-water separation, water harvesting. To conclude, we encapsulate challenges, potential solutions, future directions for improving these
Language: Английский
Citations
1
Heliyon, Journal Year: 2024, Volume and Issue: 11(1), P. e41465 - e41465
Published: Dec. 24, 2024
Language: Английский
Citations
6
Bioactive Materials, Journal Year: 2024, Volume and Issue: 40, P. 261 - 274
Published: June 14, 2024
Language: Английский
Citations
4
International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 139725 - 139725
Published: Jan. 1, 2025
Language: Английский
Citations
0
Journal of Colloid and Interface Science, Journal Year: 2025, Volume and Issue: unknown, P. 137658 - 137658
Published: April 1, 2025
Language: Английский
Citations
0