High performance soft fiber-reinforced sodium alginate/polyacrylamide double-network hydrogels DOI
Xiaodan Wang, Dan Xie,

Wenwen Hou

et al.

Progress in Natural Science Materials International, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 1, 2024

Language: Английский

The Optimization of Culture Conditions for Injectable Recombinant Collagen Hydrogel Preparation Using Machine Learning DOI Creative Commons
Mengyu Li, Long Zhao, Yanan Ren

et al.

Gels, Journal Year: 2025, Volume and Issue: 11(2), P. 141 - 141

Published: Feb. 17, 2025

Injectable recombinant collagen hydrogels (RCHs) are crucial in biomedical applications. Culture conditions play an important role the preparation of hydrogels. However, determining characteristics under certain and optimal swiftly still remain challenging tasks. In this study, a machine learning approach was introduced to explore correlation between hydrogel culture determine conditions. The study focused on four key factors as independent variables: initial substrate concentration, reaction temperature, pH level, time, while dependent variable elastic modulus To analyze impact these modulus, mathematical models were employed, including multiple linear regression (ML), decision tree (DT), support vector (SVM), neural network (NN). theoretical outputs NN closest actual values. Therefore, proved be most suitable model. Subsequently, identified concentration 15% (W/V), temperature 4 °C, 7.0, time 12 h. prepared specific exhibited predicted 15,340 Pa, approaching that natural cartilage.

Language: Английский

Citations

0
Bionic Hydrogel-based Stretchable Devices for Bioelectronics Applications DOI
Yitao Zhang,

Yiqing Yuan,

Haiyang Duan

et al.

Journal of Bionic Engineering, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 19, 2025

Language: Английский

Citations

0
Regional‐Specific Decellularized Meniscus Extracellular Matrix Elastic Nanofiber Aerogels Regulate Meniscal Regeneration and Vascularization DOI Open Access
Moran Huang, Yangfan Ding,

Jize Dong

et al.

Advanced Healthcare Materials, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 21, 2025

Abstract The meniscus is a heterogeneous structure with spatial distribution of cells and vessels. Promoting healing remains challenging, especially in its avascular inner region. ideal repair mode shall promote while maintaining local avascularity to prevent pathological changes from vascular invasion. Given the natural biochemical components native meniscus, decellularized extracellular matrix (dmECM) shows promise for repair. Compared homogeneous dmECM, regional‐specific dmECM (RS‐dmECM) appears offer greater potential constructing structures. Furthermore, there currently no study on effects RS‐dmECM vascularization. Thus, prepared found dmECM‐Outer induced stem fibrochondrogenic differentiation, dmECM‐Inner chondrogenic differentiation inhibited angiogenesis through suppressing peroxisome proliferators‐activated receptors signaling pathway. Subsequently, poly(lactic acid)/gelatin/dmECM elastic 3D nanofiber aerogels (PG‐dmECM) are fabricated meniscal area defects rabbit model. PG‐Outer promotes fibrocartilage regeneration without significant effect In contrast, PG‐Inner achieves cartilage inhibits Moreover, compressive stress can reach 117 kPa, comparable that area. This may have within

Language: Английский

Citations

0
Bioinspired design of strong, tough and slippery hydrogels beyond the natural soft tissues DOI
Kai Chen, Qin Chen, Xiaodong Yan

et al.

Materials Today Chemistry, Journal Year: 2025, Volume and Issue: 45, P. 102633 - 102633

Published: March 9, 2025

Language: Английский

Citations

0
Enhanced interlayer adhesion and regulated tribological behaviors of 3D printed poly(ether ether ketone) by annealing DOI
Zhengwei Lin, Rui Guo, Yang Lyu

et al.

Tribology International, Journal Year: 2024, Volume and Issue: 202, P. 110362 - 110362

Published: Nov. 2, 2024

Language: Английский

Citations

1
Design Strategy, On-Demand Control, and Biomedical Engineering Applications of Wet Adhesion DOI
Tingting Luo,

Xingqi Lu,

Hui Ma

et al.

Langmuir, Journal Year: 2024, Volume and Issue: 40(49), P. 25729 - 25757

Published: Nov. 22, 2024

The adhesion of tissues to external devices is fundamental numerous critical applications in biomedical engineering, including tissue and organ repair, bioelectronic interfaces, adhesive robotics, wearable electronics, sensing actuation, as well medical monitoring, treatment, healthcare. A key challenge this context that are typically situated aqueous dynamic environments, which poses a bottleneck further advancements these fields. Wet technology (WAT) presents an effective solution issue. In review, we summarize the three major design strategies control methods wet adhesion, comprehensively systematically introducing latest WAT field engineering. First, single mechanism under frameworks introduced. Second, for summarized, spatiotemporal control, detachment reversible control. Third, systematic summary discussion engineering research education were presented, with particular focus on innovative such tissue-electronic interface devices, ingestible end-effector components, vivo microrobots, instruments equipment. Finally, opportunities challenges encountered development adhesives advanced performance application prospects discussed.

Language: Английский

Citations

1
Biomolecule-based hydrogels as delivery systems for limbal stem cell transplantation: A review DOI
Fuyan Wang,

Yuehe Xu,

Qingjun Zhou

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 280, P. 135778 - 135778

Published: Sept. 18, 2024

Language: Английский

Citations

0
High performance soft fiber-reinforced sodium alginate/polyacrylamide double-network hydrogels DOI
Xiaodan Wang, Dan Xie,

Wenwen Hou

et al.

Progress in Natural Science Materials International, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 1, 2024

Language: Английский

Citations

0