Preparation and antioxidant properties of tannic acid/copper ion nanozyme hybrid nanofibrous membranes DOI Creative Commons

Qiao Wu,

Jingshu Xiao,

Zhuang Hu

et al.

RSC Advances, Journal Year: 2024, Volume and Issue: 14(48), P. 35743 - 35753

Published: Jan. 1, 2024

Excess free radicals can have some negative effects on human health. In this paper, a nanozyme was successfully constructed by the coordination of copper ions and tannic acid, its structure elemental distribution were determined Fourier transform infrared spectroscopy, scanning electron microscopy X-ray photoelectron spectroscopy. Free radical scavenging experiments confirmed that it possessed superoxide dismutase-like activity, catalase-like hydroxyl ability. The results thermogravimetric analysis demonstrated good thermal stability. A polyacrylonitrile hybrid nanofibrous membrane loaded with Cu/TA electrospinning technology, maximum rate DPPH ABTS reach 64.22% 58.44%, respectively. nanofiber also exhibited ability to protect cells from oxidative stress damage. Therefore, has broad application prospect in fields such as food preservation biomedicine.

Language: Английский

Defect-engineered nanoscale metal-organic frameworks as self-cascade antioxidation nanozymes for targeted therapy of cisplatin-induced acute kidney injury DOI

Wenfeng Guo,

Tingting Wang, Huirong Li

et al.

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 163893 - 163893

Published: May 1, 2025

Language: Английский

Citations

0
Cu-Fe Bimetallic Peroxide-Based Nanozyme with Microenvironment-Triggered Cascade Catalysis for Synergistic Hydroxyl Radical, Nitric Oxide, and Oxygen Generation in Trimodal Wound Infection Therapy DOI Creative Commons
Wei Liu, Yuan Fang, Ping Xu

et al.

Materials Today Bio, Journal Year: 2025, Volume and Issue: 32, P. 101912 - 101912

Published: May 28, 2025

Language: Английский

Citations

0
Highly Stretchable, Self‐Healable, and Conductive Gelatin Methacryloyl Hydrogel for Long‐Lasting Wearable Tactile Sensors DOI Creative Commons
Zhikang Li, Bin Wang, Jijian Lu

et al.

Advanced Science, Journal Year: 2025, Volume and Issue: unknown

Published: May 29, 2025

Abstract Constructing hydrogels with both remarkable mechanical and self‐healing properties is highly desirable for soft electronics, yet remains challenging due to conflicting demands on chemical bonds polymer chain mobility. Herein, a stretchable, self‐healing, conductive gelatin methacryloyl (GelMA) hydrogel developed by incorporating polyvinyl alcohol, N‐(2‐amino‐2‐oxoethyl)‐2‐propenamide, sodium tetraborate, chloride into GelMA, followed two‐step polymerization process. The introduced novel interpenetrating networks, hierarchical hydrogen (weak strong H‐bonds), borate ester (BEBs) synergistically improve the strength, concurrently function as sacrificial energy dissipation under deformation. Moreover, constructed reversible BEBs weak H‐bonds enable autonomous at room temperature. resulting achieves stretchability (≈160%), tensile strength (≈130 kPa), efficiency (86%), surpassing previously reported GelMA hydrogels. Importantly, strain sensor demonstrated, featuring high gauge factor (≈3.28), ultra‐low detection limit (0.1%), excellent recovery of sensitivity (≈100%) range (≈75%) after damage. Successful monitoring subtle large‐scale human motions original healed sensors highlights device's durability longevity. This study provides promising approach rational design practical application in wearable bioelectronics.

Language: Английский

Citations

0
Thermosensitive Hydrogel Integrated with Bimetallic Nano‐Enzymes for Modulating the Microenvironment in Diabetic Wound Beds DOI Creative Commons

Chuwei Zhang,

Xiaoyi Zhang, Fei Li

et al.

Advanced Science, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 16, 2024

Abstract Effective regulation and reconstruction of the microenvironment are critical for regeneration chronic wounds. Diabetic wounds, in particular, pose a significant clinical challenge due to increased oxidative stress dysfunctional healing processes. In this study, novel therapeutic strategy is developed using 3D copper‐magnesium bimetallic antioxidant nano‐enzymes (Cu/Mg‐MOF) mitigate reactive oxygen species (ROS) restore redox balance through electron transfer. To optimize delivery, thermo‐sensitive hydrogel composed chitosan (CS) ε ‐polylysine (PL) designed, serving as an efficient carrier nano‐enzymes. This Cu/Mg‐MOF@CS/PL exhibits excellent physical properties, including injectability, softness, biocompatibility, making it ideal application diabetic wound model, treatment with significantly accelerated healing, closure rate 90.6% by day 14, compared just 55.4% untreated group. The effectively promoted key aspects such collagen deposition, re‐epithelialization, angiogenesis, immunomodulation. These findings underscore potential promising system enhancing

Language: Английский

Citations

2
Preparation and antioxidant properties of tannic acid/copper ion nanozyme hybrid nanofibrous membranes DOI Creative Commons

Qiao Wu,

Jingshu Xiao,

Zhuang Hu

et al.

RSC Advances, Journal Year: 2024, Volume and Issue: 14(48), P. 35743 - 35753

Published: Jan. 1, 2024

Excess free radicals can have some negative effects on human health. In this paper, a nanozyme was successfully constructed by the coordination of copper ions and tannic acid, its structure elemental distribution were determined Fourier transform infrared spectroscopy, scanning electron microscopy X-ray photoelectron spectroscopy. Free radical scavenging experiments confirmed that it possessed superoxide dismutase-like activity, catalase-like hydroxyl ability. The results thermogravimetric analysis demonstrated good thermal stability. A polyacrylonitrile hybrid nanofibrous membrane loaded with Cu/TA electrospinning technology, maximum rate DPPH ABTS reach 64.22% 58.44%, respectively. nanofiber also exhibited ability to protect cells from oxidative stress damage. Therefore, has broad application prospect in fields such as food preservation biomedicine.

Language: Английский

Citations

1