Journal of Semiconductors,
Journal Year:
2025,
Volume and Issue:
46(1), P. 011603 - 011603
Published: Jan. 1, 2025
Abstract
Heart
rate
variability
(HRV)
that
can
reflect
the
dynamic
balance
between
sympathetic
nervous
and
parasympathetic
of
human
autonomic
system
(ANS)
has
attracted
considerable
attention.
However,
traditional
electrocardiogram
(ECG)
devices
for
HRV
analysis
are
bulky,
hard
wires
needed
to
attach
measuring
electrodes
chest,
resulting
in
poor
wearable
experience
during
long-term
measurement.
Compared
with
that,
electronics
enabling
continuously
cardiac
signals
monitoring
assessment
provide
a
desirable
promising
approach
helping
subjects
determine
sleeping
issues,
cardiovascular
diseases,
or
other
threats
physical
mental
well-being.
Until
now,
significant
progress
advances
have
been
achieved
applications
predicting
In
this
review,
latest
integration
as
well
practical
health
included.
The
commonly
used
methods
physiological
briefly
summarized.
Furthermore,
we
highlighted
research
on
concerning
diverse
such
stress
estimation,
drowsiness
detection,
etc.
Lastly,
current
limitations
integrated
concluded,
possible
solutions
direction
outlined.
ACS Nano,
Journal Year:
2023,
Volume and Issue:
17(6), P. 5211 - 5295
Published: March 9, 2023
Humans
rely
increasingly
on
sensors
to
address
grand
challenges
and
improve
quality
of
life
in
the
era
digitalization
big
data.
For
ubiquitous
sensing,
flexible
are
developed
overcome
limitations
conventional
rigid
counterparts.
Despite
rapid
advancement
bench-side
research
over
last
decade,
market
adoption
remains
limited.
To
ease
expedite
their
deployment,
here,
we
identify
bottlenecks
hindering
maturation
propose
promising
solutions.
We
first
analyze
achieving
satisfactory
sensing
performance
for
real-world
applications
then
summarize
issues
compatible
sensor-biology
interfaces,
followed
by
brief
discussions
powering
connecting
sensor
networks.
Issues
en
route
commercialization
sustainable
growth
sector
also
analyzed,
highlighting
environmental
concerns
emphasizing
nontechnical
such
as
business,
regulatory,
ethical
considerations.
Additionally,
look
at
future
intelligent
sensors.
In
proposing
a
comprehensive
roadmap,
hope
steer
efforts
towards
common
goals
guide
coordinated
development
strategies
from
disparate
communities.
Through
collaborative
efforts,
scientific
breakthroughs
can
be
made
sooner
capitalized
betterment
humanity.
Advanced Materials,
Journal Year:
2022,
Volume and Issue:
34(21)
Published: Jan. 19, 2022
Abstract
Cardiovascular
diseases
remain
the
leading
cause
of
death
worldwide.
The
rapid
development
flexible
sensing
technologies
and
wearable
pressure
sensors
have
attracted
keen
research
interest
been
widely
used
for
long‐term
real‐time
cardiovascular
status
monitoring.
Owing
to
compelling
characteristics,
including
light
weight,
wearing
comfort,
high
sensitivity
pulse
pressures,
physiological
waveforms
can
be
precisely
continuously
monitored
by
health
Herein,
an
overview
human
wave
monitoring
is
presented,
with
a
focus
on
transduction
mechanism,
microengineering
structures,
related
applications
in
condition
assessment.
conceptualizations
methods
acquisition
pathological
information
system
are
outlined.
biomechanics
arterial
waves
working
mechanism
various
sensors,
triboelectric,
piezoelectric,
magnetoelastic,
piezoresistive,
capacitive,
optical
also
subject
systematic
debate.
Exemple
measurement
based
structured
devices
then
summarized.
Finally,
discussion
opportunities
challenges
that
face,
as
well
their
potential
intelligent
personalized
healthcare
given
conclusion.
Chemical Society Reviews,
Journal Year:
2022,
Volume and Issue:
51(9), P. 3759 - 3793
Published: Jan. 1, 2022
Skin
bioelectronics
are
considered
as
an
ideal
platform
for
personalised
healthcare
because
of
their
unique
characteristics,
such
thinness,
light
weight,
good
biocompatibility,
excellent
mechanical
robustness,
and
great
skin
conformability.
Recent
advances
in
skin-interfaced
have
promoted
various
applications
precision
medicine.
Particularly,
long-term,
continuous
health
monitoring
offer
powerful
analysis
a
broad
spectrum
statuses,
providing
route
to
early
disease
diagnosis
treatment.
In
this
review,
we
discuss
(1)
representative
sensing
devices,
(2)
material
structure
selection,
device
properties,
wireless
technologies
towards
monitoring,
(3)
applications:
acquisition
electrophysiological,
biophysical,
biochemical
signals,
comprehensive
(4)
rational
guidelines
the
design
future
monitoring.
Long-term,
advanced
will
open
unprecedented
opportunities
timely
prevention,
screening,
diagnosis,
treatment,
demonstrating
promise
revolutionise
traditional
medical
practices.
Chemical Reviews,
Journal Year:
2024,
Volume and Issue:
124(2), P. 455 - 553
Published: Jan. 4, 2024
In
the
era
of
Internet-of-things,
many
things
can
stay
connected;
however,
biological
systems,
including
those
necessary
for
human
health,
remain
unable
to
connected
global
Internet
due
lack
soft
conformal
biosensors.
The
fundamental
challenge
lies
in
fact
that
electronics
and
biology
are
distinct
incompatible,
as
they
based
on
different
materials
via
functioning
principles.
particular,
body
is
curvilinear,
yet
typically
rigid
planar.
Recent
advances
design
have
generated
tremendous
opportunities
wearable
bioelectronics,
which
may
bridge
gap,
enabling
ultimate
dream
healthcare
anyone,
anytime,
anywhere.
We
begin
with
a
review
historical
development
healthcare,
indicating
significant
trend
healthcare.
This
followed
by
focal
point
discussion
about
new
design,
particularly
low-dimensional
nanomaterials.
summarize
material
types
their
attributes
designing
bioelectronic
sensors;
we
also
cover
synthesis
fabrication
methods,
top-down,
bottom-up,
combined
approaches.
Next,
discuss
energy
challenges
progress
made
date.
addition
front-end
devices,
describe
back-end
machine
learning
algorithms,
artificial
intelligence,
telecommunication,
software.
Afterward,
integration
systems
been
applied
various
testbeds
real-world
settings,
laboratories
preclinical
clinical
environments.
Finally,
narrate
remaining
conjunction
our
perspectives.
ACS Nano,
Journal Year:
2021,
Volume and Issue:
15(12), P. 18822 - 18847
Published: Nov. 29, 2021
The
noble
metal
nanoparticle
has
been
widely
utilized
as
a
plasmonic
unit
to
enhance
biosensors,
by
leveraging
its
electric
and/or
optical
properties.
Integrated
with
the
"flexible"
feature,
it
further
enables
opportunities
in
developing
healthcare
products
conformal
and
adaptive
fashion,
such
wrist
pulse
tracers,
body
temperature
trackers,
blood
glucose
monitors,
etc.
In
this
work,
we
present
holistic
review
of
recent
advance
flexible
biosensors
for
sector.
technical
spectrum
broadly
covers
design
selection
substrate,
process
integrate
units,
exploration
different
types
monitor
human
temperature,
glucose,
ions,
gas,
motion
indicators,
well
their
applications
surface-enhanced
Raman
scattering
(SERS)
colorimetric
detections.
Their
fundamental
working
principles
structural
innovations
are
scoped
summarized.
challenges
prospects
articulated
regarding
critical
importance
continued
progress
improve
living
quality.
Sensors,
Journal Year:
2023,
Volume and Issue:
23(23), P. 9498 - 9498
Published: Nov. 29, 2023
Disease
diagnosis
and
monitoring
using
conventional
healthcare
services
is
typically
expensive
has
limited
accuracy.
Wearable
health
technology
based
on
flexible
electronics
gained
tremendous
attention
in
recent
years
for
patient
owing
to
attractive
features,
such
as
lower
medical
costs,
quick
access
data,
ability
operate
transmit
data
harsh
environments,
storage
at
room
temperature,
non-invasive
implementation,
mass
scaling,
etc.
This
provides
an
opportunity
disease
pre-diagnosis
immediate
therapy.
sensors
have
opened
a
new
area
of
personalized
by
accurately
measuring
physical
states
biochemical
signals.
Despite
the
progress
date
development
wearable
sensors,
there
are
still
several
limitations
accuracy
collected,
precise
diagnosis,
early
treatment.
necessitates
advances
applied
materials
structures
artificial
intelligence
(AI)-enabled
extract
target
signals
accurate
clinical
decision-making
efficient
care.
In
this
paper,
we
review
two
significant
aspects
smart
sensors.
First,
offer
overview
most
improving
sensor
performance
physical,
chemical,
biosensors,
focusing
materials,
structural
configurations,
transduction
mechanisms.
Next,
use
AI
combination
with
big
processing,
self-learning,
power-efficiency,
real-time
acquisition
intelligent
sensing
platform.
Finally,
present
challenges
future
opportunities
associated
Biosensors,
Journal Year:
2022,
Volume and Issue:
12(5), P. 292 - 292
Published: May 2, 2022
Cardiovascular
diseases
(CVDs)
are
the
leading
cause
of
death
globally.
An
effective
strategy
to
mitigate
burden
CVDs
has
been
monitor
patients'
biomedical
variables
during
daily
activities
with
wearable
technology.
Nowadays,
technological
advance
contributed
wearables
technology
by
reducing
size
devices,
improving
accuracy
sensing
be
devices
relatively
low
energy
consumption
that
can
manage
security
and
privacy
patient's
medical
information,
have
adaptability
any
data
storage
system,
reasonable
costs
regard
traditional
scheme
where
patient
must
go
a
hospital
for
an
electrocardiogram,
thus
contributing
serious
option
in
diagnosis
treatment
CVDs.
In
this
work,
we
review
commercial
noncommercial
used
CVD
variables.
Our
main
findings
revealed
usually
include
smart
wristbands,
patches,
smartwatches,
they
generally
such
as
heart
rate,
blood
oxygen
saturation,
electrocardiogram
data.
Noncommercial
focus
on
monitoring
photoplethysmography
data,
mostly
accelerometers
smartwatches
detecting
atrial
fibrillation
failure.
However,
using
without
healthy
personal
habits
will
disappointing
results
health.
Cell Reports Physical Science,
Journal Year:
2021,
Volume and Issue:
2(8), P. 100541 - 100541
Published: Aug. 1, 2021
Cardiovascular
disease
(CVD)
is
a
major
global
health
problem.
Living
with
diseases
like
CVD
often
requires
long-term
monitoring,
for
which
flexible
and
conformable
sensors
are
employed.
The
developments
in
materials,
devices,
integrated
electronic
systems,
the
Internet
of
Things
(IoT),
edge
computing
enable
real-time
convenient
measurement
detection
signals.
Herein,
we
review
latest
surveillance
various
physiological
signals
CVD.
First,
variety
that
can
monitor
summarized.
Then,
different
mechanisms
principles
monitoring
pulse
signals,
as
well
sensor
electrocardiogram
(ECG),
phonocardiogram
(PCG),
seismocardiogram/ballistocardiogram
(SCG/BCG),
apexcardiogram
(ACG)
discussed.
Finally,
future
research
directions
proposed
based
on
current
landscape.
Sensors,
Journal Year:
2022,
Volume and Issue:
22(12), P. 4653 - 4653
Published: June 20, 2022
Flexible
sensors
are
low
cost,
wearable,
and
lightweight,
as
well
having
a
simple
structure
per
the
requirements
of
engineering
applications.
Furthermore,
for
many
potential
applications,
such
human
health
monitoring,
robotics,
wearable
electronics,
artificial
intelligence,
flexible
require
high
sensitivity
stretchability.
Herein,
this
paper
systematically
summarizes
latest
progress
in
development
sensors.
The
review
briefly
presents
state
art
sensors,
including
materials
involved,
sensing
mechanisms,
manufacturing
methods,
monitoring
soft
robotic
Moreover,
provides
perspectives
on
challenges
field
prospect