Chemical Engineering Journal, Journal Year: 2023, Volume and Issue: 461, P. 141965 - 141965
Published: Feb. 18, 2023
Language: Английский
Chemical Reviews, Journal Year: 2024, Volume and Issue: 124(2), P. 455 - 553
Published: Jan. 4, 2024
In the era of Internet-of-things, many things can stay connected; however, biological systems, including those necessary for human health, remain unable to connected global Internet due lack soft conformal biosensors. The fundamental challenge lies in fact that electronics and biology are distinct incompatible, as they based on different materials via functioning principles. particular, body is curvilinear, yet typically rigid planar. Recent advances design have generated tremendous opportunities wearable bioelectronics, which may bridge gap, enabling ultimate dream healthcare anyone, anytime, anywhere. We begin with a review historical development healthcare, indicating significant trend healthcare. This followed by focal point discussion about new design, particularly low-dimensional nanomaterials. summarize material types their attributes designing bioelectronic sensors; we also cover synthesis fabrication methods, top-down, bottom-up, combined approaches. Next, discuss energy challenges progress made date. addition front-end devices, describe back-end machine learning algorithms, artificial intelligence, telecommunication, software. Afterward, integration systems been applied various testbeds real-world settings, laboratories preclinical clinical environments. Finally, narrate remaining conjunction our perspectives.
Language: Английский
Citations
155
Materials Horizons, Journal Year: 2023, Volume and Issue: 10(8), P. 2800 - 2823
Published: Jan. 1, 2023
Hydrogels have been attracting increasing attention for application in wearable electronics, due to their intrinsic biomimetic features, highly tunable chemical-physical properties (mechanical, electrical, etc.), and excellent biocompatibility. Among many proposed varieties of hydrogels, conductive polymer-based hydrogels (CPHs) emerged as a promising candidate future sensor designs, with capability realizing desired features using different tuning strategies ranging from molecular design (with low length scale 10-10 m) micro-structural configuration (up 10-2 m). However, considerable challenges remain be overcome, such the limited strain sensing range mechanical strength, signal loss/instability caused by swelling/deswelling, significant hysteresis signals, de-hydration induced malfunctions, surface/interfacial failure during manufacturing/processing. This review aims offer targeted scan recent advancements CPH based technology, establishment dedicated structure-property relationships lab advanced manufacturing routes potential scale-up production. The CPHs sensors is also explored, suggested new research avenues prospects included.
Language: Английский
Citations
130
Bioelectronic Medicine, Journal Year: 2023, Volume and Issue: 9(1)
Published: Aug. 2, 2023
The fourth industrial revolution has led to the development and application of health monitoring sensors that are characterized by digitalization intelligence. These have extensive applications in medical care, personal management, elderly sports, other fields, providing people with more convenient real-time services. However, these face limitations such as noise drift, difficulty extracting useful information from large amounts data, lack feedback or control signals. artificial intelligence provided powerful tools algorithms for data processing analysis, enabling intelligent monitoring, achieving high-precision predictions decisions. By integrating Internet Things, intelligence, sensors, it becomes possible realize a closed-loop system functions collection, online diagnosis, treatment recommendations. This review focuses on healthcare enhanced technologies aspects materials, device structure, integration, scenarios. Specifically, this first introduces great advances wearable respiration rate, heart pulse, sweat, tears; implantable cardiovascular nerve signal acquisition, neurotransmitter monitoring; soft electronics precise therapy. Then, recent volatile organic compound detection highlighted. Next, current developments human-machine interfaces, AI-enhanced multimode self-sustainable systems reviewed. Last, perspective future directions further research is also provided. In summary, fusion will provide intelligent, convenient, secure services next-generation biomedical applications.
Language: Английский
Citations
105
Small, Journal Year: 2022, Volume and Issue: 18(47)
Published: Oct. 10, 2022
Hydrogel electronics have attracted growing interest for emerging applications in personal healthcare management, human-machine interaction, etc. Herein, a "doping then gelling" strategy to synthesize supramolecular PANI/PAA hydrogel with specific strand entangled network is proposed, by doping the PANI acrylic acid (AA) monomers avoid aggregation. The high-density electrostatic interaction between PAA and chains serves as dynamic bond initiate entanglement, enabling PAA/PANI ultra-stretchability (2830%), high breaking strength (120 kPa), rapid self-healing properties. Moreover, hydrogel-based sensor strain sensitivity (gauge factor = 12.63), responding time (222 ms), robust conductivity-based sensing behavior under cyclic stretching developed. A set of precisely monitor human movements also demonstrated, indicating promising application prospect wearable devices.
Language: Английский
Citations
86
Biosensors and Bioelectronics, Journal Year: 2023, Volume and Issue: 225, P. 115090 - 115090
Published: Jan. 20, 2023
Language: Английский
Citations
85
ACS Sensors, Journal Year: 2023, Volume and Issue: 8(2), P. 465 - 481
Published: Feb. 10, 2023
Flexible sweat sensors have found widespread potential applications for long-term wear and tracking real-time monitoring of human health. However, the main substrate currently used in common flexible is thin film, which has disadvantages such as poor air permeability need additional wearables. In this Review, recent progress been systematically summarized by types methods sensors. addition, Review introduces compares performance based on film textile substrates fiber/yarn. Finally, opportunities suggestions development are presented summarizing integration body sites.
Language: Английский
Citations
67
Nanomaterials, Journal Year: 2023, Volume and Issue: 13(7), P. 1270 - 1270
Published: April 3, 2023
Plasmonics is a revolutionary concept in nanophotonics that combines the properties of both photonics and electronics by confining light energy to nanometer-scale oscillating field free electrons, known as surface plasmon. Generation, processing, routing, amplification optical signals at nanoscale hold promise for communications, biophotonics, sensing, chemistry, medical applications. Surface plasmons manifest themselves confined oscillations, allowing nanoantennas, ultra-compact detectors, state-of-the-art sensors, data storage, harvesting designs. facilitate resonant characteristics nanostructures guiding controlling nanoscale. metamaterials enable advancement many photonic designs with unparalleled capabilities, including subwavelength waveguides, nanoresonators, super- hyper-lenses, concentrators. Alternative plasmonic materials have been developed be incorporated low losses controlled along semiconductor-process compatibility. This review describes processes behind range It pays special attention topics enhancement collective effects nanostructures. The advances these research are expected transform domain photonics, metamaterials, their various
Language: Английский
Citations
60
ACS Applied Nano Materials, Journal Year: 2023, Volume and Issue: 6(7), P. 5042 - 5074
Published: March 31, 2023
Fast technological progress has sped up the growth of telemedicine, mobile e-health services, and healthcare monitoring, which, nowadays, are technologies in high demand medical field analytical sensing. Biosensing device design promoted forefront research topics wherein new sensing have been developed. In this regard, nanomaterials had a crucial role novel biosensors based on emerged as detective tools for several biomolecules. Most remarkably sensitive selective to detect cancer biomarkers, toxins foods, drugs, pathogenic microorganisms, cholesterol, pesticides, nucleic acids, glucose, heavy-metal contaminations, other bioanalytes under different platforms at extraordinarily low concentrations (nanomolar, picomolar, or femtomolar). A comprehensive review used biosensing is offered herein. Specifically, offers point view, highlighting covering exhaustively kinds (<500 nm) human diseases through biosensing. sense, we organize them into organic, inorganic, carbon-based, thus offering guide selecting best nanomaterial specific detection. Further, it provides roadmap real-time utilization commercial scale. Also, addresses some aspects use applications The discussed paper highlights immense potential implement nanocomposites initial examination point-of-care testing.
Language: Английский
Citations
57
ACS Sensors, Journal Year: 2023, Volume and Issue: 8(4), P. 1766 - 1773
Published: March 29, 2023
Monitoring the acetaminophen dosage is important to prevent occurrence of adverse reactions such as liver failure and kidney damage. Traditional approaches monitoring mainly rely on invasive blood collection. Herein, we developed a noninvasive microfluidic-based wearable plasmonic sensor achieve simultaneous sweat sampling drug for vital signs. The fabricated employs an Au nanosphere cone array key sensing component, which poses substrate with surface-enhanced Raman scattering (SERS) activity noninvasively sensitively detect fingerprint molecules based its unique SERS spectrum. enabled sensitive detection quantification at concentrations low 0.13 μM. We further evaluated integrated spectrometer in drug-administered subjects. These results indicated that could measure levels reflect metabolism. sensors have revolutionized technology by adopting label-free molecular tracking methods point-of-care management.
Language: Английский
Citations
54
Chemical Engineering Journal, Journal Year: 2023, Volume and Issue: 472, P. 145110 - 145110
Published: July 29, 2023
Language: Английский
Citations
48