Science China Materials, Journal Year: 2023, Volume and Issue: 66(8), P. 3347 - 3360
Published: May 19, 2023
Language: Английский
Advanced Fiber Materials, Journal Year: 2022, Volume and Issue: 4(3), P. 361 - 389
Published: Feb. 11, 2022
Language: Английский
Citations
247
Chemical Reviews, Journal Year: 2024, Volume and Issue: 124(2), P. 455 - 553
Published: Jan. 4, 2024
In the era of Internet-of-things, many things can stay connected; however, biological systems, including those necessary for human health, remain unable to connected global Internet due lack soft conformal biosensors. The fundamental challenge lies in fact that electronics and biology are distinct incompatible, as they based on different materials via functioning principles. particular, body is curvilinear, yet typically rigid planar. Recent advances design have generated tremendous opportunities wearable bioelectronics, which may bridge gap, enabling ultimate dream healthcare anyone, anytime, anywhere. We begin with a review historical development healthcare, indicating significant trend healthcare. This followed by focal point discussion about new design, particularly low-dimensional nanomaterials. summarize material types their attributes designing bioelectronic sensors; we also cover synthesis fabrication methods, top-down, bottom-up, combined approaches. Next, discuss energy challenges progress made date. addition front-end devices, describe back-end machine learning algorithms, artificial intelligence, telecommunication, software. Afterward, integration systems been applied various testbeds real-world settings, laboratories preclinical clinical environments. Finally, narrate remaining conjunction our perspectives.
Language: Английский
Citations
135
ACS Nano, Journal Year: 2021, Volume and Issue: 15(12), P. 18822 - 18847
Published: Nov. 29, 2021
The noble metal nanoparticle has been widely utilized as a plasmonic unit to enhance biosensors, by leveraging its electric and/or optical properties. Integrated with the "flexible" feature, it further enables opportunities in developing healthcare products conformal and adaptive fashion, such wrist pulse tracers, body temperature trackers, blood glucose monitors, etc. In this work, we present holistic review of recent advance flexible biosensors for sector. technical spectrum broadly covers design selection substrate, process integrate units, exploration different types monitor human temperature, glucose, ions, gas, motion indicators, well their applications surface-enhanced Raman scattering (SERS) colorimetric detections. Their fundamental working principles structural innovations are scoped summarized. challenges prospects articulated regarding critical importance continued progress improve living quality.
Language: Английский
Citations
129
Advanced Functional Materials, Journal Year: 2022, Volume and Issue: 32(27)
Published: April 28, 2022
The practical applications of skin-interfaced sensors and devices in daily life hinge on the rational design surface wettability to maintain device integrity achieve improved sensing performance under complex hydrated conditions. Various bio-inspired strategies have been implemented engineer desired for varying Although bodily fluids can negatively affect performance, they also provide a rich reservoir health-relevant information sustained energy next-generation stretchable self-powered devices. As result, manipulation are critical effectively control liquid behavior enhanced performance. with engineered collect analyze health biomarkers while being minimally affected by or ambient humid environments. harvesters benefit from powering on-body electronics. In this review, we first summarize commonly used approaches tune target toward By considering existing challenges, discuss opportunities as small fraction potential future developments, which lead new class use digital personalized medicine.
Language: Английский
Citations
120
npj Flexible Electronics, Journal Year: 2022, Volume and Issue: 6(1)
Published: Aug. 5, 2022
Abstract Flexible electronics are playing an increasingly important role in human health monitoring and healthcare diagnosis. Strong adhesion on tissue would be ideal for reducing interface resistance motion artifacts, but arising problems such as skin irritation, rubefaction, pain upon device removal have hampered their utility. Here, inspired by the temperature reversibility of hydrogen bonding, a skin-friendly conductive hydrogel with multiple-hydrogen bonds was designed using biocompatible poly(vinyl alcohol) (PVA), phytic acid (PA), gelatin (Gel). The obtained PVA/PA/Gel (PPG) temperature-triggered tunable mechanic could reliably adhere to detect electrophysiological signals under hot compress while readily removed cool compress. Furthermore, additional advantages transparency, breathability, antimicrobial activity PPG ensure its long-time wearable value skin. It is both environmentally friendly cost saving waste during production can recycled based reversible physical bonding. sensor expected good application prospects record monitoring.
Language: Английский
Citations
108
Advanced Materials, Journal Year: 2023, Volume and Issue: unknown
Published: Aug. 28, 2023
The rise of flexible and stretchable electronics has revolutionized biosensor techniques for probing biological systems. Particularly, electrochemical sensors (FSECSs) enable the in situ quantification numerous biochemical molecules different entities owing to their exceptional sensitivity, fast response, easy miniaturization. Over past decade, fabrication application FSECSs have significantly progressed. This review highlights key developments electrode functionalization. It delves into sensing various biomarkers, including metabolites, electrolytes, signaling molecules, neurotransmitters from systems, encompassing outer epidermis, tissues/organs vitro vivo, living cells. Finally, considering preparation applications, current challenges future opportunities are discussed.
Language: Английский
Citations
72
Journal of Materials Chemistry A, Journal Year: 2023, Volume and Issue: 11(33), P. 17336 - 17372
Published: Jan. 1, 2023
The emerging smart fibers and textiles have been regarded as ideal building blocks to weave flexible wearable electronics, which hold great promise in the upcoming artificial intelligence (AI) Internet of Things (IoT) era.
Language: Английский
Citations
71
Materials & Design, Journal Year: 2023, Volume and Issue: 229, P. 111917 - 111917
Published: April 7, 2023
Timely and accurate assessment of wounds during the wound healing process is key for correct diagnosis treatment decisions repair. However, traditional management strategies often fail to provide timely information on status, thereby delaying or misleading treatments. Smart dressings that enable in situ real-time monitoring wound-related biomarkers, early on-demand adverse events, such as bacterial infection inflammation, by integrating wearable sensors, advanced drug delivery systems wireless communication technology have recently been developed could improve management. In this review, we provided an overview including temperature, pH, uric acid, glucose, reactive oxygen (ROS), enzymes, related events exiting sensors detecting these biomarkers based colorimetric, fluorimetric electrochemical approaches. Examples smart integrate controllable functions triggered both endogenous exogenous stimuli, all-in-one dressing capable treatment, major challenges exciting opportunities are presented comprehensively discussed.
Language: Английский
Citations
67
Science Advances, Journal Year: 2024, Volume and Issue: 10(12)
Published: March 20, 2024
Stretchable bioelectronics has notably contributed to the advancement of continuous health monitoring and point-of-care type care. However, microscale nonconformal contact locally dehydrated interface limit performance, especially in dynamic environments. Therefore, hydrogels can be a promising interfacial material for stretchable due their unique advantages including tissue-like softness, water-rich property, biocompatibility. there are still practical challenges terms electrical homogeneity, monolithic integration with devices. Here, we report synthesis homogeneously conductive polyacrylamide hydrogel an exceptionally low impedance (~21 ohms) reasonably high conductivity (~24 S/cm) by incorporating polyaniline-decorated poly(3,4-ethylenedioxythiophene:polystyrene). We also establish robust adhesion (interfacial toughness: ~296.7 J/m
Language: Английский
Citations
50
SusMat, Journal Year: 2024, Volume and Issue: 4(4)
Published: May 29, 2024
Abstract Wearable strain sensors have attracted research interest owing to their potential within digital healthcare, offering smarter tracking, efficient diagnostics, and lower costs. Unlike rigid sensors, fiber‐based ones compete with flexibility, durability, adaptability body structures as well eco‐friendliness environment. Here, the sustainable wearable for health are reviewed, material, fabrication, practical healthcare aspects explored. Typical predicated on various sensing modalities, be it resistive, capacitive, piezoelectric, or triboelectric, explained analyzed according strengths weaknesses toward fabrication applications. The applications in spanning from area networks, intelligent management, medical rehabilitation multifunctional systems also evaluated. Moreover, create a more complete network, wired wireless methods of data collection examples machine learning elaborated detail. Finally, prevailing challenges prospective insights into advancement novel fibers, enhancement precision wearability, establishment seamlessly integrated critically summarized offered. This endeavor not only encapsulates present landscape but lays foundation future breakthroughs sensor technology domain health.
Language: Английский
Citations
18