Carbohydrate Polymers,
Journal Year:
2023,
Volume and Issue:
315, P. 120934 - 120934
Published: April 20, 2023
Peripheral
nerve
repair
following
injury
is
one
of
the
most
serious
problems
in
neurosurgery.
Clinical
outcomes
are
often
unsatisfactory
and
associated
with
a
huge
socioeconomic
burden.
Several
studies
have
revealed
great
potential
biodegradable
polysaccharides
for
improving
regeneration.
We
review
here
promising
therapeutic
strategies
involving
different
types
their
bio-active
composites
promoting
Within
this
context,
polysaccharide
materials
widely
used
forms
highlighted,
including
guidance
conduits,
hydrogels,
nanofibers
films.
While
conduits
hydrogels
were
as
main
structural
scaffolds,
other
films
generally
additional
supporting
materials.
also
discuss
issues
ease
implementation,
drug
release
properties
outcomes,
together
future
directions
research.
Advanced Science,
Journal Year:
2023,
Volume and Issue:
10(28)
Published: Aug. 23, 2023
The
development
of
self-healing
conductive
hydrogels
is
critical
in
electroactive
nerve
tissue
engineering.
Typical
materials
such
as
polypyrrole
(PPy)
are
commonly
used
to
fabricate
artificial
conduits.
Moreover,
the
field
engineering
has
advanced
toward
use
products
hyaluronic
acid
(HA)
hydrogels.
Although
HA-modified
PPy
films
prepared
for
various
biological
applications,
cell-matrix
interaction
mechanisms
remain
poorly
understood;
furthermore,
there
no
reports
on
PPy-injectable
peripheral
repair.
Therefore,
this
study,
a
electroconductive
hydrogel
(HASPy)
from
HA,
cystamine
(Cys),
and
pyrrole-1-propionic
(Py-COOH),
with
injectability,
biodegradability,
biocompatibility,
nerve-regenerative
capacity
constructed.
directly
targets
interleukin
17
receptor
A
(IL-17RA)
promotes
expression
genes
proteins
relevant
Schwann
cell
myelination
mainly
by
activating
(IL-17)
signaling
pathway.
injected
into
rat
sciatic
nerve-crush
injury
sites
investigate
its
regeneration
vivo
found
promote
functional
recovery
remyelination.
This
study
may
help
understanding
mechanism
interactions
provide
new
insights
potential
HASPy
an
scaffold
neural
regeneration.
Food Hydrocolloids,
Journal Year:
2024,
Volume and Issue:
151, P. 109753 - 109753
Published: Jan. 16, 2024
Edible
coating
plays
an
important
role
in
preventing
fruit
rot
and
prolonging
the
shelf
life
of
fruit.
However,
a
large
amount
water
will
accumulate
on
surface
through
respiratory
metabolism
during
storage,
leading
to
dissolution
coating.
Therefore,
it
is
develop
water-resistant
coatings
extend
bananas.
In
this
work,
gluconolactone
(GDL)
was
used
slowly
generate
gluconic
acid,
which
protonated
amino
groups
whey
protein
isolate
(WPI)
enhanced
electrostatic
interaction
between
WPI
sodium
alginate
(SA)
form
cross-linked
composite
The
introduction
increased
contact
angle
value
films
from
47.1°
102.1°.
exhibited
excellent
mechanical
properties,
resistance,
UV
shielding
self-healing,
gas-selective
transmission.
experiment
banana
preservation
proved
that
could
effectively
slow
down
loss
bananas,
retard
ripening
browning,
bananas
for
6
days
at
25
°C
50%
RH.
multifunctional
has
reference
design
self-healing
coating,
shows
good
potential
perishable
fruits.
International Journal of Biological Macromolecules,
Journal Year:
2024,
Volume and Issue:
270, P. 132287 - 132287
Published: May 10, 2024
Damage
to
the
integrity
of
preservation
coating
on
fruit
surface
will
seriously
affect
shelf
life
fruit.
In
this
work,
strong
hydrogen
bond
interaction
between
xanthan
gum
(XG)
and
konjac
glucomannan
(KGM)
could
form
hydrogel
films
with
self-healing
properties.
The
introduction
gallic
acid
(GA)
was
beneficial
further
improve
antioxidant
activity
UV
shielding
performance
composite
films.
Surprisingly,
mechanical
properties
gas
(water
vapor,
O
Journal of Polymer Science,
Journal Year:
2022,
Volume and Issue:
61(1), P. 7 - 43
Published: Oct. 19, 2022
Abstract
Polysaccharides
possessing
distinctive
properties,
such
as
biocompatibility,
biodegradability,
and
nontoxicity,
are
promising
matrices
for
hydrogels.
However,
the
polysaccharides‐based
hydrogels
have
poor
mechanical
which
is
a
major
limitation
their
applications.
In
recent
years,
researches
on
double‐network
(DN)
with
outstanding
properties
gained
increasing
attention.
Therefore,
main
research
orientation
to
combine
benefits
of
both
materials
broaden
applications
in
various
fields.
This
paper
reviews
progress
polysaccharide‐based
DN
(PDN)
that
show
great
advantages
mechanical,
physiochemical
biodegradability
so
on.
The
preparation,
structure,
unique
different
PDN
discussed
detail.
Moreover,
we
summarize
biomedical
energy
storage
conversion
breaking
through
limitations
opening
new
avenue
future
development.
Marine Drugs,
Journal Year:
2022,
Volume and Issue:
20(6), P. 396 - 396
Published: June 15, 2022
The
continuous
advances
in
surgical
procedures
require
research
regarding
materials
with
applications.
Biopolymers
are
widely
studied
since
they
usually
provide
a
biocompatible,
biodegradable,
and
non-toxic
material.
Among
them,
chitosan
is
promising
material
for
the
development
of
formulations
devices
applications
due
to
its
intrinsic
bacteriostatic,
fungistatic,
hemostatic,
analgesic
properties.
A
wide
range
products
has
been
manufactured
this
polymer,
including
scaffolds,
sponges,
hydrogels,
meshes,
membranes,
sutures,
fibers,
nanoparticles.
growing
interest
researchers
use
chitosan-based
tissue
regeneration
obvious
extensive
application
bone,
nervous
tissue,
cartilage,
soft
tissues.
Chitosan
can
serve
as
substance
administration
cell-growth
promoters,
well
support
cellular
growth.
Another
interesting
hemostasis
control,
remarkable
results
studies
comparing
dressings
traditional
cotton
gauzes.
In
addition,
or
chitosan-coated
formulation
antimicrobial
activity
that
highly
appreciated
not
only
but
also
sutures
meshes.
