ACS Applied Polymer Materials,
Journal Year:
2024,
Volume and Issue:
7(1), P. 258 - 267
Published: Dec. 27, 2024
Diabetic
wounds
are
extremely
difficult
to
heal
due
the
long
duration
and
high
recurrence
rate.
The
bacterial
infection
caused
by
elevated
blood
glucose
negatively
affects
speed
of
wound
healing.
In
this
article,
radially
oriented
nanofibers
containing
natural
antimicrobial
agent
purslane
were
prepared
electrostatic
spinning.
Subsequently,
asiaticoside
was
loaded
onto
surface
fibers
spraying.
experimental
results
indicated
that
radial
nanofiber
membranes
exhibited
uniform
diameter
distribution,
suitable
water
vapor
permeability,
good
hydrophilicity
as
well
excellent
antibacterial
performance
biocompatibility.
Due
ordered
arrangement,
healing
ability,
regular
granulation
tissue
growth,
collagen
deposition.
More
importantly,
fiber
structure
significantly
promoted
cell
proliferation
adhesion.
Based
on
these
results,
with
a
have
potential
application
prospects
in
field
chronic
diabetic
ACS Applied Materials & Interfaces,
Journal Year:
2024,
Volume and Issue:
16(13), P. 15970 - 15980
Published: March 19, 2024
Despite
the
rapid
development
of
tissue
adhesives,
flaws
including
allergies,
poor
stability,
and
indiscriminate
double-sided
adhesive
properties
limit
their
application
in
medical
field.
In
this
work,
Janus
polyurethane
patches
were
spontaneously
prepared
by
adjusting
difference
functional
group
distribution
between
top
bottom
sides
patch
during
emulsion
drying.
Consequently,
adhesion
was
exhibited
on
surface,
while
surface
can
easily
adhere
to
metals,
polymers,
glasses,
tissues.
The
strength
pork
skin
two
surfaces
is
more
than
5
times.
quaternary
ammonium
salt
hydrophilic
components
enable
removal
absorption
water
from
achieve
wet
adhesion.
Animal
experiments
have
demonstrated
that
multifunctional
promote
wound
closure
healing
infected
wounds.
This
facile
effective
strategy
construct
provides
a
promising
method
for
tissue-adhesives.
Biomacromolecules,
Journal Year:
2024,
Volume and Issue:
25(4), P. 2438 - 2448
Published: March 19, 2024
The
treatment
of
infected
wounds
faces
substantial
challenges
due
to
the
high
incidence
and
serious
infection-related
complications.
Natural-based
hydrogel
dressings
with
favorable
antibacterial
properties
strong
applicability
are
urgently
needed.
Herein,
we
developed
a
composite
by
constructing
multiple
networks
loading
ciprofloxacin
for
wound
healing.
was
synthesized
via
Schiff
base
reaction
between
carboxymethyl
chitosan
oxidized
sodium
alginate,
followed
polymerization
acrylamide
monomer.
resultant
dressing
possessed
good
self-healing
ability,
considerable
compression
strength,
reliable
fatigue
resistance.
In
vitro
assessment
showed
that
effectively
eliminated
bacteria
exhibited
an
excellent
biocompatibility.
model
Journal of Materials Chemistry B,
Journal Year:
2024,
Volume and Issue:
12(22), P. 5377 - 5390
Published: Jan. 1, 2024
In
this
work,
a
hydrogel
dressing
for
controlled
release
of
hydrogen
sulfide
is
developed
the
repair
scalded
wounds.
It
exhibits
responsive
H
2
S
based
on
ROS
concentration,
allowing
precise
modulation
wound
microenvironment.
ACS Biomaterials Science & Engineering,
Journal Year:
2024,
Volume and Issue:
10(8), P. 4771 - 4790
Published: July 10, 2024
Microneedles
are
a
novel
drug
delivery
system
that
offers
advantages
such
as
safety,
painlessness,
minimally
invasive
administration,
simplicity
of
use,
and
controllable
delivery.
As
type
polymer
microneedle
with
three-dimensional
network
structure,
hydrogel
microneedles
(HMNs)
possess
excellent
biocompatibility
biodegradability
encapsulate
various
therapeutic
drugs
while
maintaining
activity,
thus
attracting
significant
attention.
Recently,
they
have
been
widely
employed
to
promote
wound
healing
demonstrated
favorable
effects.
Although
there
reviews
about
HMNs,
few
them
focus
on
management.
Herein,
we
present
comprehensive
overview
the
design
preparation
methods
particular
emphasis
their
application
status
in
healing,
including
acute
infected
diabetic
scarless
healing.
Finally,
examine
limitations
HMNs
management
provide
suggestions
for
future
research
directions.
