Bioengineering,
Journal Year:
2025,
Volume and Issue:
12(5), P. 438 - 438
Published: April 22, 2025
(1)
Background:
Tannic
acid
(TA),
a
water-soluble
polyphenol
extensively
found
in
numerous
plant
species,
possesses
antimicrobial,
anti-inflammatory,
antioxidant,
and
adhesive
properties.
This
scoping
review
aims
to
synthesize
existing
knowledge
on
TA
applications
unveil
its
potential
uses
dentistry.
(2)
Methods:
A
comprehensive
search
across
six
electronic
databases
(PubMed,
Cochrane,
Embase,
Scopus,
Web
of
Science,
Opengrey)
was
conducted
October
2024.
Two
reviewers
performed
the
screening
risk
bias
analysis
independently
following
PRISMA-ScR
guidelines.
The
findings
are
presented
narrative
summary.
(3)
Results:
Five
hundred
twelve
records
were
identified
from
databases.
After
removing
duplicates
applying
eligibility
criteria,
ninety-six
studies
ultimately
included
this
review.
Results
indicate
that
has
been
employed
managing
dentin
hypersensitivity,
dental
caries,
periodontal
mucosal
diseases,
as
well
dentition
defects
with
prostheses.
Furthermore,
displays
enhancing
performance
bonding
adhesives,
root
canal
irrigants,
filling
materials.
However,
it
is
noteworthy
exhibit
varied
experimental
settings,
inconsistent
outcome
measures,
lack
extensive
clinical
research,
insufficient
observation
periods.
(4)
Conclusions:
promising
biomaterial
various
fields,
such
endodontics,
periodontology,
prosthodontics,
public
health.
Its
properties
warrant
future
exploration
unleash
these
potentials
provide
robust
scientific
evidence
guides
practice
advances
oral
healthcare.
Advanced Healthcare Materials,
Journal Year:
2024,
Volume and Issue:
13(22)
Published: May 21, 2024
The
repair
and
regeneration
of
cartilage
has
always
been
a
hot
topic
in
medical
research.
Cartilage
organoids
(CORGs)
are
special
tissue
created
using
engineering
techniques
outside
the
body.
These
engineered
tissues
provide
models
that
simulate
complex
biological
functions
cartilage,
opening
new
possibilities
for
regenerative
medicine
treatment
strategies.
However,
it
is
crucial
to
establish
suitable
matrix
scaffolds
cultivation
CORGs.
In
recent
years,
utilizing
hydrogel
culture
stem
cells
induce
their
differentiation
into
chondrocytes
emerged
as
promising
method
vitro
construction
this
review,
methods
establishing
CORGs
summarized
an
overview
advantages
limitations
matrigel
such
provided.
Furthermore,
importance
ECM
alternative
substitutes
Matrigel,
alginate,
peptides,
silk
fibroin,
DNA
derivatives
discussed,
pros
cons
these
hydrogels
outlined.
Finally,
challenges
future
directions
research
discussed.
It
hoped
article
provides
valuable
references
design
development
Advanced Science,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 3, 2025
Abstract
Dentin
hypersensitivity
(DH),
marked
by
exposed
dentinal
tubules,
presents
as
a
sharp
toothache
triggered
stimuli
and
subsides
when
the
are
removed.
To
address
limitations
of
current
commercial
desensitizers
in
terms
acid
resistance,
friction
stability,
black
phosphorus
nanosheet‐composited
methacrylate
gelatin
hydrogel
(GelMA/BP)
is
developed
for
DH
treatment,
leveraging
synergistic
effects
photothermal
therapy
biomineralization.
Incorporating
BP
nanosheet
provided
GelMA/BP
with
stable
response
continuous
release
phosphate
anions,
which
blocked
tubules
converting
light
energy
into
heat
initiating
In
vitro
desensitizing
showed
that
tubule
diameter
GelMA/BP50
group
(0−1.13
µm)
significantly
reduced
compared
to
DH‐model
(0−3.14
µm).
The
achieved
an
86%
occlusion
rate,
resistance
80%,
76%,
long‐term
stability
74%.
vivo
studies
further
validated
efficacy
GelMA/BP50,
showing
reduction
(0−0.37
rate
79%,
alleviated
increased
intake
weight.
These
results
demonstrate
this
acts
effective
sealant,
offering
promising
clinical
benefits
topical
treatment
DH.
Advanced Functional Materials,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 19, 2025
Abstract
Dentin
hypersensitivity
(DH),
caused
by
the
exposure
of
dentin
tubules,
is
a
common
complaint
dental
patients.
Although
occlusion
exposed
tubules
primary
treatment
approach,
complex
oral
environment,
and
multiple
simultaneous
requirements
often
hinder
its
implementation.
In
this
study,
strawberry‐shaped
hemispheric
Janus
particles
(JPs)
are
synthesized,
their
use
in
DH
evaluated
vitro
an
animal
model.
The
side
JPs
modified
with
polymers
quaternary
ammonium
salts
(QASs)
to
form
superhydrophobic
coating
antibiofilm
properties,
while
flat
catechol
groups
able
strong
bonds
dentin.
Even
after
1
h
ultrasonication
or
1000
rounds
thermal
cycling,
completely
occluded
JPs.
Moreover,
biofilm
formation
not
observed,
area
living
bacteria
less
than
1%
compared
blank
control
sodium
fluoride
(NaF)‐treated
groups.
rat
model,
fixed
specimens
at
day
3,
much
earlier
obtained
commonly
used
NaF.
These
results
demonstrate
that
can
provide
novel
approach
DH.
Macromolecular Rapid Communications,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 26, 2025
Rapid
gelation
hydrogels
have
garnered
significant
attention
due
to
their
simple
synthesis,
high
efficiency,
low
cost,
and
environmental
sustainability,
which
enable
meet
critical
demands
for
scalability
green
chemistry
unlocking
opportunities
across
diverse
application
fields.
This
review
synthesizes
current
advancements
in
the
mechanisms
driving
rapid
gelation,
encompassing
self-assembly
processes,
MXene-triggered
redox-driven
reactions,
coordination
chemistry,
Schiff
base
other
innovative
strategies.
The
discussion
extends
far-reaching
applications,
from
advanced
therapeutic
platforms
high-performance
energy
devices
precision
sensors
adaptive
soft
actuators.
By
critically
evaluating
recent
progress
addressing
existing
challenges,
this
not
only
deepens
understanding
of
mechanisms,
but
also
provides
scientific
insights
practical
guidance
foster
interdisciplinary
integration
drive
material
innovation
synthesis
technologies.
Advanced Science,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 27, 2025
Abstract
Dental
caries
is
a
global
oral
dilemma
leading
to
demineralization
of
tooth
hard
tissues
and
exposure
dentinal
tubules
(DTs).
Multifunctional
restorative
strategies,
including
remineralization,
antibacterial
properties,
DT
occlusion,
are
urgently
needed
for
dental
management
but
remain
significant
challenge.
Herein,
the
polyaspartic
acid‐calcium‐lanthanum
suspension
(5
g
L
−1
‐3.06
м‐0.34
м)
followed
by
phosphate
solution
(2.04
adopted
conduct
polyelectrolyte‐cation
complexes
pre‐precursor
process.
This
strategy,
first
time,
successfully
induces
La‐doped
intrafibrillar
mineralization
collagen
fibrils
with
lanthanum‐doped
hydroxyapatite
(La‐HAp).
After
sequential
application
two
media,
demineralized
dentin
fully
remineralized
DTs
deeply
occluded
depth
100
µm
La‐HAp
after
7
d
incubation
in
artificial
saliva
or
cavity
rabbit.
The
demonstrates
properties
against
cariogenic
bacteria
(
Streptococcus
mutans
)
both
vitro
vivo,
its
mechanical
almost
restored
those
intact
dentin.
media
cause
no
apparent
irritation
mucosa
pulp.
Hence,
this
multifunctional
strategy
confers
surface
blocks
invasion
through
DTs,
providing
insight
into
clinical
accompanied
hypersensitivity.
