Simple theranostics nanoagent for precision suppression of tumor growth and Metastasis: A traditional fermented product having a novel functional breakthrough DOI

Pengmin Liu,

Rong Dai,

Juan Li

et al.

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 500, P. 156545 - 156545

Published: Oct. 10, 2024

Language: Английский

Coordination engineering of FeCo dual single-atom nanozymes with photothermal-enhanced cascaded catalysis for efficient pancreatic cancer immunotherapy DOI

Wen-kuan Huang,

Zeyuan Zhang,

Jingqi Chen

et al.

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 496, P. 154203 - 154203

Published: July 21, 2024

Language: Английский

Citations

8
Predicting anti-tumor efficacy of multi-functional nanomedicine on decellularized hepatocellular carcinoma-on-a-chip DOI

Yueqing Chen,

Genhui Lin,

Ziyi Wang

et al.

Biosensors and Bioelectronics, Journal Year: 2024, Volume and Issue: 264, P. 116668 - 116668

Published: Aug. 12, 2024

Language: Английский

Citations

5
Synchronous Interference of Dual Metabolic Pathways Mediated by H2S Gas/GOx for Augmenting Tumor Microwave Thermal Therapy DOI
Shimei Li, Qiong Wu,

Zengzhen Chen

et al.

ACS Applied Materials & Interfaces, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 11, 2025

Sublethal tumor cells have an urgent need for energy, making it common them to switch metabolic phenotypes between glycolysis and oxidative phosphorylation (OXPHOS) compensatory energy supply; thus, the synchronous interference of dual pathways limiting level is essential in inhibiting sublethal growth. Herein, a multifunctional nanoplatform Co-MOF-loaded anethole trithione (ADT) myristyl alcohol (MA), modified with GOx hyaluronic acid (HA) was developed, namely, CAMGH. It could synchronously interfere including OXPHOS restrict adenosine triphosphate (ATP) supply, achieving inhibition tumors after microwave (MW) thermal therapy. Under low-power MW irradiation, CAMGH induced certain damage while ensuring safety surrounding normal tissues. The loaded consumed glucose tumors, undoubtedly blocking main supply pathway, glycolytic pathway. Then, H

Language: Английский

Citations

0
sEmerging glucose oxidase-delivering nanomedicines for enhanced tumor therapy DOI

Kai‐Yue Song,

Ming Jiang, Bailong Tao

et al.

Journal of Controlled Release, Journal Year: 2025, Volume and Issue: 381, P. 113580 - 113580

Published: Feb. 28, 2025

Language: Английский

Citations

0
Development of a Highly Efficient NIR-II Phototherapeutic Agent for Fluorescence Imaging-Guided Synergistic PTT/PDT/Chemotherapy of Colorectal Cancer DOI
Ji Liu, Lei Liang,

Ping Gan

et al.

Journal of Medicinal Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

NIR-II-triggered phototherapy presents a noninvasive, resistance-free alternative therapeutic approach with deeper tissue penetration and improved imaging of deep tumors. However, many NIR-II phototherapeutic agents suffer from low fluorescence quantum yields, poor photothermal conversion efficiency (PCE), reduced efficacy due to the upregulation heat shock protein HSP70. This study develops small-molecule agent (IRF) high yield (17.4%), excellent PCE (96.8%) for therapy (PTT), photodynamic (PDT) activity. To decrease thermal resistance during phototherapy, IRF evodiamine (EVO) were loaded onto hyaluronic acid (HA)-modified nanoparticles, creating multifunctional nanoplatform termed EVO/IRF@HA NPs. NPs can actively target tumors via HA moiety. Upon 980 nm laser irradiation, increases temperature content reactive oxygen species synergistic PTT/PDT. Importantly, EVO effectively inhibits overexpression HSP70, enabling combined PTT/PDT/chemotherapy effective colorectal cancer (CRC) treatment.

Language: Английский

Citations

0
Enhanced sequential osteosarcoma therapy using a 3D-Printed bioceramic scaffold combined with 2D nanosheets via NIR-II photothermal-chemodynamic synergy DOI
Guangyu Jian, Si Wang, Xinlu Wang

et al.

Bioactive Materials, Journal Year: 2025, Volume and Issue: 50, P. 540 - 555

Published: May 1, 2025

Language: Английский

Citations

0
Nanomedicine-driven tumor glucose metabolic reprogramming for enhanced cancer immunotherapy DOI Creative Commons

Chen‐Wei Jiang,

Minglu Tang,

Yun Su

et al.

Acta Pharmaceutica Sinica B, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Language: Английский

Citations

0
Redox homeostasis disruptors enhanced cuproptosis effect for synergistic photothermal/chemodynamic therapy DOI
Zhen Liu, Junhong Ling,

Nan Wang

et al.

Journal of Colloid and Interface Science, Journal Year: 2024, Volume and Issue: 678, P. 1060 - 1074

Published: Aug. 31, 2024

Language: Английский

Citations

2
Advances in H2O2-supplying materials for tumor therapy: synthesis, classification, mechanisms, and applications DOI
Xu Zhang, Mao Li, Ya‐ling Tang

et al.

Biomaterials Science, Journal Year: 2024, Volume and Issue: 12(16), P. 4083 - 4102

Published: Jan. 1, 2024

Hydrogen peroxide (H 2 O ) as a reactive oxygen species produced by cellular metabolism can be used in antitumor therapy.

Language: Английский

Citations

1
Simple theranostics nanoagent for precision suppression of tumor growth and Metastasis: A traditional fermented product having a novel functional breakthrough DOI

Pengmin Liu,

Rong Dai,

Juan Li

et al.

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 500, P. 156545 - 156545

Published: Oct. 10, 2024

Language: Английский

Citations

0