Sensors and Actuators B Chemical,
Journal Year:
2020,
Volume and Issue:
320, P. 128432 - 128432
Published: June 9, 2020
Research
has
focused
on
graphene
for
developing
the
next
generation
of
label-free
biosensors,
capable
highly
sensitive
and
specific
detection
DNA
or
other
biomolecules.
The
binding
charged
analytes
to
one-atom
thick
layer
can
greatly
affect
its
electronic
properties.
However,
is
chemically
inert,
thus
surface
functionalization
through
chemical
treatment
typically
necessary
immobilize
receptors
target
biological
analyte
graphene.
In
this
work,
we
use
gas-phase
synthesized
gold
nanoparticles
(Au
NPs)
functionalize
bind
a
aptamer
surface.
employed
in
liquid
gated
field-effect
transistor
(FET)
configuration
detect
hybridization
complementary
strand,
as
well
protein
streptavidin,
at
attomolar
level
(aM,
10−18
mol
L−1).
sensor
shows
high
dynamic
detecting
range
from
aM
picomolar
(pM)
levels
(10-18
10-12
L−1),
discriminate
between
strand
single
nucleotide
polymorphism
(SNP)
containing
achieves
limit
low
15
aM.
suggests
that
decorating
biosensors
with
Au
NPs
magnetron
sputtering
inert
gas
condensing
technique
promising
method
biosensor
functionalization,
particularly
larger-area
sensors
employ
two-dimensional
materials
such
Advanced Healthcare Materials,
Journal Year:
2017,
Volume and Issue:
6(19)
Published: Aug. 10, 2017
Abstract
This
study
reports
biosensing
using
graphene
field‐effect
transistors
with
the
aid
of
pyrene‐tagged
DNA
aptamers,
which
exhibit
excellent
selectivity,
affinity,
and
stability
for
Escherichia
coli
(
E.
)
detection.
The
aptamer
is
employed
as
sensing
probe
due
to
its
advantages
such
high
affinity
toward
small
molecules
even
whole
cells.
change
carrier
density
in
probe‐modified
attachment
discussed
theoretically
first
time
also
verified
experimentally.
conformational
binding
brings
negatively
charged
close
surface,
increasing
hole
efficiently
achieving
electrical
induces
holes
graphene,
are
pumped
into
channel
from
contact
electrodes.
mobility,
correlates
gate
voltage
signal
APG‐FETs,
analyzed
optimized
here.
performance
low
detection
limit,
sensitivity,
outstanding
selectivity
biosensor
paves
way
develop
biosensors
bacterial
Microchimica Acta,
Journal Year:
2020,
Volume and Issue:
187(8)
Published: July 12, 2020
Abstract
This
review
(162
references)
focuses
on
two-dimensional
carbon
materials,
which
include
graphene
as
well
its
allotropes
varying
in
size,
number
of
layers,
and
defects,
for
their
application
electrochemical
sensors.
Many
preparation
methods
are
known
to
yield
materials
often
simply
addressed
graphene,
but
show
huge
variations
physical
chemical
properties
therefore
sensing
performance.
The
first
section
briefly
reviews
the
most
promising
latest
achievements
synthesis
based
growth
delamination
techniques,
such
vapor
deposition,
liquid
phase
exfoliation
via
sonication
or
mechanical
forces,
oxidative
procedures
ranging
from
exfoliation.
Two-dimensional
highly
attractive
be
integrated
a
wide
field
applications.
Here,
is
examined
recognition
layer
sensors
like
field-effect
transistors,
chemiresistors,
impedance-based
devices
voltammetric
amperometric
sensor
performance
evaluated
material’s
perspective
view
revealed
impact
structure
defects
2D
different
transducing
technologies.
It
concluded
that
carbon-based
strongly
related
method
combination
with
electrical
transduction
technique.
Future
perspectives
address
challenges
transfer
lab
market.
Advanced Materials Technologies,
Journal Year:
2018,
Volume and Issue:
4(2)
Published: Dec. 13, 2018
Abstract
Flexible
wearable
sensors
are
expected
to
be
the
future
generation
of
personal
health
monitoring
devices
with
large‐area,
multimodal,
multipoint
sensing,
and
complicated
data
analysis.
However,
multimaterial
interfacial
coalescence
mechanical
matching
critically
challenge
advancement
flexible
multifunction
integration.
Graphene,
characteristic
carbon
sheet
2D
material,
is
endowed
good
transparency,
stability,
superior
electron
mobility,
heat
conductivity,
excellent
flexibility,
performance.
A
summary
progresses
graphene‐based
in
terms
material
processing,
sensor
configuration,
property
presented.
Various
assembly
structures
could
perform
different
electrical
behaviors
unitary
graphene
material.
The
diversity
temperature,
humidity,
pressure,
strain,
integrated
multifunctional
developed
recent
years
detailed.
Benefitting
from
commendable
performance
high
durability,
promote
practical
applications
body
temperature
monitoring,
voice
recognition,
pulse‐beating,
motion,
respiration
detection.
Finally,
research
following
development
trends
challenges
develop
their
potential
human
human–machine
interfaces
discussed.
Sensors and Actuators B Chemical,
Journal Year:
2020,
Volume and Issue:
320, P. 128432 - 128432
Published: June 9, 2020
Research
has
focused
on
graphene
for
developing
the
next
generation
of
label-free
biosensors,
capable
highly
sensitive
and
specific
detection
DNA
or
other
biomolecules.
The
binding
charged
analytes
to
one-atom
thick
layer
can
greatly
affect
its
electronic
properties.
However,
is
chemically
inert,
thus
surface
functionalization
through
chemical
treatment
typically
necessary
immobilize
receptors
target
biological
analyte
graphene.
In
this
work,
we
use
gas-phase
synthesized
gold
nanoparticles
(Au
NPs)
functionalize
bind
a
aptamer
surface.
employed
in
liquid
gated
field-effect
transistor
(FET)
configuration
detect
hybridization
complementary
strand,
as
well
protein
streptavidin,
at
attomolar
level
(aM,
10−18
mol
L−1).
sensor
shows
high
dynamic
detecting
range
from
aM
picomolar
(pM)
levels
(10-18
10-12
L−1),
discriminate
between
strand
single
nucleotide
polymorphism
(SNP)
containing
achieves
limit
low
15
aM.
suggests
that
decorating
biosensors
with
Au
NPs
magnetron
sputtering
inert
gas
condensing
technique
promising
method
biosensor
functionalization,
particularly
larger-area
sensors
employ
two-dimensional
materials
such
