Peptide-directed synthesis of chiral nano-bipyramids for controllable antibacterial application DOI Creative Commons
Panpan Chen, Gaoyang Wang,

Changlong Hao

et al.

Chemical Science, Journal Year: 2022, Volume and Issue: 13(35), P. 10281 - 10290

Published: Jan. 1, 2022

The emergence of antibiotic resistance makes the therapeutic effect traditional antibiotics far from satisfactory. Here, chiral gold nano-bipyramids (GBPs) with sea cucumber-like morphology are reported, and used in fight against bacterial infection. Specifically, dipeptide d-/l-Cys-Phe (CF) caused to form a spike shape an optical anisotropy factor 0.102 at 573 nm. antibacterial effects showed that d-GBPs l-GBPs could efficiently destroy bacteria death ratio 98% 70% vitro. Also, both vivo skin infection sepsis models GBPs effectively promote wound healing prevent mice. Mechanistic studies binding affinity (1.071 ± 0.023 × 108 M-1) was 12.39-fold higher than (8.664 0.251 106 protein A Staphylococcus aureus, which further adsorption onto surface. Moreover, physical destruction cell wall by GBPs, resulted stronger for l-GBPs. Furthermore, excellent PTT d-/l-GBPs exacerbated without any side-effect. Overall, have opened new avenue improved efficacy treatment infections.

Language: Английский

Recent advances of surface enhanced Raman spectroscopy (SERS) in optical biosensing DOI Creative Commons
Dana Cialla‐May, Alois Bonifacio, Alexey V. Markin

et al.

TrAC Trends in Analytical Chemistry, Journal Year: 2024, Volume and Issue: unknown, P. 117990 - 117990

Published: Oct. 1, 2024

Language: Английский

Citations

8
Chiral Patterning of Rough Surfaces with Vortex Laser Beams: From Structured Polarization to Twisted Forces DOI Open Access
Vladimir Yu. Fedorov, Jean‐Philippe Colombier

Laser & Photonics Review, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 27, 2025

Abstract The ability to create surface structures with precisely controlled chirality remains a major challenge in laser‐matter interaction experiments. In this work, the of vortex laser beams, characterized by spiral polarization patterns and twisted wavefronts, rough metallic surfaces order is theoretically studied. Using numerical simulations based on finite‐difference time‐domain method, how spin orbital angular momenta influence inhomogeneous energy absorption at investigated optical forces that can drive topographic reorganization are generated. How different structured light fields intricate chiral features material shown. crucial role spatial inhomogeneity field generation asymmetric torque directly affect dynamics emphasized. electromagnetic show beams be used structures, expanding knowledge laser‐generated periodic opening up new possibilities for engineering.

Language: Английский

Citations

1
Atomically Thin TaSe2 Film as a High‐Performance Substrate for Surface‐Enhanced Raman Scattering DOI
Yuancai Ge, Fei Wang, Ying Yang

et al.

Small, Journal Year: 2022, Volume and Issue: 18(15)

Published: March 4, 2022

Abstract An atomically thin TaSe 2 sample, approximately containing two to three layers of nanosheets with a diameter 2.5 cm is prepared here for the first time and applied on detection various Raman‐active molecules. It achieves limit 10 −10 m rhodamine 6G The excellent surface‐enhanced Raman scattering (SERS) performance underlying mechanism are revealed using spectrum analysis density functional theory. large adsorption energy abundance filled electrons close Fermi level found play important roles in chemical enhancement mechanism. Moreover, film enables highly sensitive bilirubin serum urine samples, highlighting potential 2D SERS substrates applications clinical diagnosis, example, diagnosis jaundice caused by excess newborn children.

Language: Английский

Citations

38
Chiral nanomaterials for biosensing, bioimaging, and disease therapies DOI

Aihua Qu,

Liguang Xu, Chuanlai Xu

et al.

Chemical Communications, Journal Year: 2022, Volume and Issue: 58(92), P. 12782 - 12802

Published: Jan. 1, 2022

Chiral plasmonic nanomaterials for biosensing, bioimaging and disease therapy.

Language: Английский

Citations

31
Peptide-directed synthesis of chiral nano-bipyramids for controllable antibacterial application DOI Creative Commons
Panpan Chen, Gaoyang Wang,

Changlong Hao

et al.

Chemical Science, Journal Year: 2022, Volume and Issue: 13(35), P. 10281 - 10290

Published: Jan. 1, 2022

The emergence of antibiotic resistance makes the therapeutic effect traditional antibiotics far from satisfactory. Here, chiral gold nano-bipyramids (GBPs) with sea cucumber-like morphology are reported, and used in fight against bacterial infection. Specifically, dipeptide d-/l-Cys-Phe (CF) caused to form a spike shape an optical anisotropy factor 0.102 at 573 nm. antibacterial effects showed that d-GBPs l-GBPs could efficiently destroy bacteria death ratio 98% 70% vitro. Also, both vivo skin infection sepsis models GBPs effectively promote wound healing prevent mice. Mechanistic studies binding affinity (1.071 ± 0.023 × 108 M-1) was 12.39-fold higher than (8.664 0.251 106 protein A Staphylococcus aureus, which further adsorption onto surface. Moreover, physical destruction cell wall by GBPs, resulted stronger for l-GBPs. Furthermore, excellent PTT d-/l-GBPs exacerbated without any side-effect. Overall, have opened new avenue improved efficacy treatment infections.

Language: Английский

Citations

30