Monitoring blood pressure and cardiac function without positioning via a deep learning–assisted strain sensor array

Science Advances, Journal Year: 2023, Volume and Issue: 9(32)

Published: Aug. 11, 2023

Continuous and reliable monitoring of blood pressure cardiac function is great importance for diagnosing preventing cardiovascular diseases. However, existing approaches are bulky costly, limiting their wide applications early diagnosis. Here, we developed an intelligent system based on a conformal flexible strain sensor array deep learning neural networks. The has variety advantages, including high sensitivity, linearity, fast response recovery, isotropy. Experiments simulation synergistically verified that the can acquire high-precise feature-rich pulse waves from wrist without precise positioning. By combining high-quality with well-trained model, monitor parameters. As proof concept, further constructed wearable real-time long-term function, which may contribute to personalized health management, diagnosis, remote treatment.

Language: Английский

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Thin, soft, wearable system for continuous wireless monitoring of artery blood pressure

Nature Communications, Journal Year: 2023, Volume and Issue: 14(1)

Published: Aug. 17, 2023

Continuous monitoring of arterial blood pressure (BP) outside a clinical setting is crucial for preventing and diagnosing hypertension related diseases. However, current continuous BP instruments suffer from either bulky systems or poor user-device interfacial performance, hampering their applications in monitoring. Here, we report thin, soft, miniaturized system (TSMS) that combines conformal piezoelectric sensor array, an active adaptation unit, signal processing module, advanced machine learning method, to allow real wearable, wireless ambulatory artery BP. By optimizing the materials selection, control/sampling strategy, integration, TSMS exhibits improved performance while maintaining Grade A level measurement accuracy. Initial trials on 87 volunteers tracking two individuals prove capability as reliable product, its feasibility practical usability precise control personalized diagnosis schemes development.

Language: Английский

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Clinical Validation of a Wearable Piezoelectric Blood‐Pressure Sensor for Continuous Health Monitoring

Advanced Materials, Journal Year: 2023, Volume and Issue: 35(26)

Published: March 24, 2023

Wearable blood-pressure sensors have recently attracted attention as healthcare devices for continuous non-invasive arterial pressure (CNAP) monitoring. However, the accuracy of wearable (BP) monitoring has been controversial due to low signal quality sensors, absence an accurate transfer function convert sensor signals into BP values, and lack clinical validation regarding measurement precision. Here, a piezoelectric (WPBPS) is reported, which achieves high normalized sensitivity (0.062 kPa-1 ), fast response time (23 ms) CNAP The linear regression model designed, offering simple solution flexible values. In order verify WPBPS, trials are performed on 35 subjects aged from 20 80 s after screening. mean difference between WPBPS commercial sphygmomanometer 175 data pairs -0.89 ± 6.19 -0.32 5.28 mmHg systolic blood (SBP) diastolic (DBP), respectively. By building WPBPS-embedded wristwatch, potentially promising use convenient, portable, system cardiovascular disease diagnosis demonstrated.

Language: Английский

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Electrospun fiber-based flexible electronics: Fiber fabrication, device platform, functionality integration and applications

Progress in Materials Science, Journal Year: 2023, Volume and Issue: 137, P. 101139 - 101139

Published: May 5, 2023

Language: Английский

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Motion artefact management for soft bioelectronics

Nature Reviews Bioengineering, Journal Year: 2024, Volume and Issue: 2(7), P. 541 - 558

Published: April 15, 2024

Language: Английский

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Tough, Antifreezing, and Piezoelectric Organohydrogel as a Flexible Wearable Sensor for Human–Machine Interaction

ACS Nano, Journal Year: 2024, Volume and Issue: 18(4), P. 3720 - 3732

Published: Jan. 18, 2024

Piezoelectric hydrogel sensors are becoming increasingly popular for wearable sensing applications due to their high sensitivity, self-powered performance, and simple preparation process. However, conventional piezoelectric hydrogels lack antifreezing properties thus confronted with the liability of rupture in low temperatures owing use water as dispersion medium. Herein, a kind organohydrogel that integrates piezoelectricity, low-temperature tolerance, mechanical robustness, stable electrical performance is reported by using poly(vinylidene fluoride) (PVDF), acrylonitrile (AN), acrylamide (AAm),

Language: Английский

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Sweat permeable and ultrahigh strength 3D PVDF piezoelectric nanoyarn fabric strain sensor

Nature Communications, Journal Year: 2024, Volume and Issue: 15(1)

Published: April 25, 2024

Abstract Commercial wearable piezoelectric sensors possess excellent anti-interference stability due to their electronic packaging. However, this packaging renders them barely breathable and compromises human comfort. To address issue, we develop a PVDF nanoyarns with an ultrahigh strength of 313.3 MPa, weaving different yarns form three-dimensional fabric (3DPF) sensor using the advanced 3D textile technology. The tensile (46.0 MPa) 3DPF exhibits highest among reported flexible sensors. features anti-gravity unidirectional liquid transport that allows sweat move from inner layer near skin outer in 4 s, resulting comfortable dry environment for user. It should be noted sweating does not weaken properties 3DPF, but rather enhances. Additionally, durability comfortability are similar those commercial cotton T-shirts. This work provides strategy developing devices.

Language: Английский

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Smart Wearable Systems for Health Monitoring

Sensors, Journal Year: 2023, Volume and Issue: 23(5), P. 2479 - 2479

Published: Feb. 23, 2023

Smart wearable systems for health monitoring are highly desired in personal wisdom medicine and telemedicine. These make the detecting, monitoring, recording of biosignals portable, long-term, comfortable. The development optimization health-monitoring have focused on advanced materials system integration, number high-performance has been gradually increasing recent years. However, there still many challenges these fields, such as balancing trade-off between flexibility/stretchability, sensing performance, robustness systems. For this reason, more evolution is required to promote In regard, review summarizes some representative achievements progress monitoring. Meanwhile, a strategy overview presented about selecting materials, integrating systems, biosignals. next generation accurate, continuous, long-term will offer opportunities disease diagnosis treatment.

Language: Английский

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Wireless Technologies in Flexible and Wearable Sensing: From Materials Design, System Integration to Applications

Advanced Materials, Journal Year: 2024, Volume and Issue: 36(27)

Published: April 23, 2024

Wireless and wearable sensors attract considerable interest in personalized healthcare by providing a unique approach for remote, noncontact, continuous monitoring of various health-related signals without interference with daily life. Recent advances wireless technologies have promoted practical applications due to their significantly improved characteristics, such as reduction size thickness, enhancement flexibility stretchability, conformability the human body. Currently, most researches focus on active materials structural designs sensors, just few exceptions reflecting data transmission. This review provides comprehensive overview state-of-the-art related studies empowering sensors. The emerging functional nanomaterials utilized designing modules are highlighted, which include metals, carbons, MXenes. Additionally, outlines system-level integration flexible spanning from novel design strategies enhanced efficient transmitting wirelessly. Furthermore, introduces representative remote noninvasive physiological through on-skin implantable sensing systems. Finally, challenges, perspectives, unprecedented opportunities discussed.

Language: Английский

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Wide Range Strain Distributions on the Electrode for Highly Sensitive Flexible Tactile Sensor with Low Hysteresis

ACS Applied Materials & Interfaces, Journal Year: 2023, Volume and Issue: 15(12), P. 15096 - 15107

Published: March 21, 2023

Flexible piezoresistive tactile sensors are widely used in wearable electronic devices because of their ability to detect mechanical stimuli. However, achieving high sensitivity and low hysteresis over a broad detection range remains challenge with current sensors. To address these obstacles, we designed elastomeric micropyramid arrays different heights redistribute the strain on electrode. Furthermore, mixed single-walled carbon nanotubes micropyramids compensate for conductivity loss caused by random cracks gold film increase adhesion strength between (deposited pyramid surface) elastomer. Thus, energy sensor during deformation (∼2.52%) was effectively reduced. Therefore, under synactic effects percolation effect, tunnel multistage distribution, as-prepared exhibited (1.28 × 106 kPa-1) (4.51-54837.06 Pa). The considerably higher than those most flexible pressure microstructure design. As proof concept, were successfully applied fields health monitoring human-machine interaction.

Language: Английский

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