Materials Horizons, Journal Year: 2024, Volume and Issue: 11(20), P. 5017 - 5030
Published: Jan. 1, 2024
A biomimetic mineralized aggregates strategy has been proposed, which could obtain molecular information about sebum by surface-enhanced Raman spectroscopy.
Language: Английский
ACS Omega, Journal Year: 2024, Volume and Issue: 9(4), P. 4819 - 4830
Published: Jan. 18, 2024
One of the requirements an efficient surface-enhanced Raman spectroscopy (SERS) substrate is a developed surface morphology with high density "hot spots", nm-scale spacings between plasmonic nanoparticles. Of particular interest are architectures that could enable self-localization (enrichment) analyte in hot spots. We report straightforward method fabrication SERS substrates comply these requirements. The basis large-area film tightly packed SiO2 spheres formed by their quick self-assembling upon drop casting from solution. Thermally evaporated thin Ag layer converted thermal annealing into nanoparticles (NPs) self-assembled trenches silica spheres, i.e., places where molecules get localized deposition solution and drying. Therefore, obtained enables enrichment spots densely arranged NPs. efficiency demonstrated detection Rhodamine 6G down to 10–13 mol/L enhancement factor ∼108, as well low concentrations various nonresonant analytes, both small dye large biomolecules. approach very for implementation can be further extended using gold or other
Language: Английский
Citations
26
ACS Nano, Journal Year: 2023, Volume and Issue: 17(21), P. 21195 - 21205
Published: Oct. 20, 2023
Teeth staining is a common dental health challenge in many parts of the world. Traditional teeth whitening techniques often lead to enamel damage and soft tissue toxicity due use bioincompatible reagents continuous strong light irradiation. Herein, an "afterglow" photodynamic therapy (aPDT) for proposed, which realized by energy transition pathways intersystem crossing. The covalent hydrogen bonds formed carbon dots embedded silica nanoparticles (CDs@SiO2) facilitate passage through crossing (ISC), thereby extending half-life reactive oxygen species (ROS). degradation efficiency aPDT on dyes was higher than 95% all cases. It can thoroughly whiten eliminating stains deep without damaging structure causing any toxicity. This study illustrates superiority approach exploring carbon-dots-based nanostructures treatment oral diseases.
Language: Английский
Citations
32
Advanced Materials, Journal Year: 2023, Volume and Issue: 35(42)
Published: Sept. 19, 2023
Abstract Optogenetic modulation of brain neural activity that combines optical and electrical modes in a unitary system has recently gained robust momentum. Controlling illumination spatial coverage, designing light‐activated modulators, developing wireless light delivery data transmission are crucial for maximizing the use neuromodulation. To this end, biocompatible electrodes with enhanced optoelectrical performance, device integration multiplexed addressing, transmission, multimodal operation soft systems have been developed. This review provides an outlook uniformly illuminating large areas while spatiotemporally imaging responses upon stimulation little artifacts. Representative concepts important breakthroughs, such as head‐mounted illumination, multiple implanted fibers, micro‐light‐delivery devices, discussed. Examples techniques incorporate electrophysiological monitoring presented. Challenges perspectives posed further research efforts toward high‐density interface modulation, potential nonpharmacological neurological disease treatments stimulation.
Language: Английский
Citations
27
Coordination Chemistry Reviews, Journal Year: 2024, Volume and Issue: 510, P. 215861 - 215861
Published: April 12, 2024
Language: Английский
Citations
13
Light Science & Applications, Journal Year: 2024, Volume and Issue: 13(1)
Published: Oct. 28, 2024
Abstract We demonstrate long-range enhancement of fluorescence and Raman scattering using a dense random array Ag nanoislands (AgNIs) coated with column-structured silica (CSS) overlayer over 100 nm thickness, namely, remote plasmonic-like (RPE). The CSS layer provides physical chemical protection, reducing the impact between analyte molecules metal nanostructures. RPE plates are fabricated high productivity sputtering immersion in gold(I)/halide solution. plate significantly enhances fluorescence, even without proximity maximum factors 10 7 -fold for 2 fluorescence. is successfully applied to enhance biosensing intracellular signalling dynamics HeLa cells histological imaging oesophagus tissues. Our findings present an interesting deviation from conventional near-field theory, as they cannot be readily explained within its framework. However, based on phenomenological aspects we have demonstrated, observed likely associated resonant coupling localised surface plasmon AgNIs molecular transition dipole analyte, facilitated through structure. Although further investigation warranted fully understand underlying mechanisms, offers practical advantages, such biocompatibility, making it valuable tool biomolecular analysis chemistry, biology, medicine. anticipate that will advance versatile analytical enhanced various biological contexts.
Language: Английский
Citations
10
Annual Review of Analytical Chemistry, Journal Year: 2024, Volume and Issue: 17(1), P. 313 - 338
Published: May 3, 2024
A frontier of analytical sciences is centered on the continuous measurement molecules in or near cells, tissues, organs, within biological context situ, where molecular-level information indicative health status, therapeutic efficacy, and fundamental biochemical function host. Following completion Human Genome Project, current research aims to link genes functions an organism investigate how environment modulates functional properties organisms. New methods have been developed detect chemical changes with high spatial temporal resolution, including minimally invasive surface-enhanced Raman scattering (SERS) nanofibers using principles endoscopy (SERS nanoendoscopy) optical physiology optophysiology). Given large spectral data sets generated from these experiments, SERS nanoendoscopy optophysiology benefit advances science machine learning extract complex vibrational spectra measured by SERS. This review highlights new opportunities for intracellular, extracellular, vivo measurements arising combination nanosensing learning.
Language: Английский
Citations
8
Biosensors, Journal Year: 2024, Volume and Issue: 14(1), P. 33 - 33
Published: Jan. 10, 2024
Surface-enhanced Raman spectroscopy (SERS) has recently emerged as a potent analytical technique with significant potential in the field of brain research. This review explores applications and innovations SERS understanding pathophysiological basis diagnosis disorders. holds advantages over conventional spectroscopy, particularly terms sensitivity stability. The integration label-free presents promising opportunities for rapid, reliable, non-invasive brain-associated diseases, when combined advanced computational methods such machine learning. to deepen our enhancing diagnosis, monitoring, therapeutic interventions. Such advancements could significantly enhance accuracy clinical further brain-related processes diseases. assesses utility diagnosing disorders Alzheimer's Parkinson's stroke, cancer. Recent technological advances instrumentation techniques are discussed, including nanoparticle design, substrate materials, imaging technologies. We also explore prospects emerging trends, offering insights into new technologies, while addressing various challenges limitations associated
Language: Английский
Citations
7
Sensors and Actuators B Chemical, Journal Year: 2024, Volume and Issue: 413, P. 135721 - 135721
Published: April 30, 2024
Language: Английский
Citations
6
Sensors and Actuators B Chemical, Journal Year: 2023, Volume and Issue: 393, P. 134248 - 134248
Published: July 6, 2023
Language: Английский
Citations
15
Applied Materials Today, Journal Year: 2024, Volume and Issue: 38, P. 102217 - 102217
Published: May 6, 2024
Language: Английский
Citations
5