Biosensors and Bioelectronics,
Journal Year:
2024,
Volume and Issue:
250, P. 116079 - 116079
Published: Jan. 28, 2024
Following
the
global
COVID-19
pandemic
triggered
by
SARS-CoV-2,
need
for
rapid,
specific
and
cost-effective
point-of-care
diagnostic
solutions
remains
paramount.
Even
though
is
no
longer
a
public
health
emergency,
disease
still
poses
threat
leading
to
deaths,
it
continues
change
with
risk
of
new
variants
emerging
causing
surge
in
cases
deaths.
Here,
we
address
urgent
SARS-CoV-2.
We
propose
multiplexed
DNA-based
sensing
platform
that
utilizes
inkjet-printed
nanostructured
gold
electrodes
an
battery-free
near-field
communication
(NFC)
potentiostat
simultaneous
quantitative
detection
two
SARS-CoV-2
genes,
ORF1ab
N
gene.
The
strategy
based
on
formation
RNA-DNA
sandwich
structure
leads
highly
electrochemical
output.
providing
large
surface
area
enable
efficient
binding
increase
sensitivity.
NFC
enables
rapid
measurements
real-time
data
analysis
via
smartphone
application,
making
accessible
portable.
With
advantages
speed
(5
min),
simplicity,
sensitivity
(low
pM
range,
∼450%
signal
gain)
cost-effectiveness,
proposed
promising
alternative
diagnostics
high-throughput
complements
toolkit.
ACS Sensors,
Journal Year:
2023,
Volume and Issue:
8(9), P. 3276 - 3293
Published: Aug. 3, 2023
Electrochemical
affinity
biosensors
are
evolving
at
breakneck
speed,
strengthening
and
colonizing
more
niches
drawing
unimaginable
roadmaps
that
increasingly
make
them
protagonists
of
our
daily
lives.
They
achieve
this
by
combining
their
intrinsic
attributes
with
those
acquired
leveraging
the
significant
advances
occurred
in
(nano)materials
technology,
bio(nano)materials
nature-inspired
receptors,
gene
editing
amplification
technologies,
signal
detection
processing
techniques.
The
aim
Perspective
is
to
provide,
support
recent
representative
illustrative
literature,
an
updated
critical
view
repertoire
opportunities,
innovations,
applications
offered
electrochemical
fueled
key
alliances
indicated.
In
addition,
imminent
challenges
these
biodevices
must
face
new
directions
which
they
envisioned
as
players
discussed.
Critical Reviews in Analytical Chemistry,
Journal Year:
2023,
Volume and Issue:
54(8), P. 2888 - 2899
Published: May 16, 2023
Continuous
monitoring
of
pathogens
finds
applications
in
environmental,
medical,
and
food
industry
settings.
Quartz
crystal
microbalance
(QCM)
is
one
the
promising
methods
for
real-time
detection
bacteria
viruses.
QCM
a
technology
that
utilizes
piezoelectric
principles
to
measure
mass
commonly
used
detecting
chemicals
adhering
surface.
Due
its
high
sensitivity
rapid
times,
biosensors
have
attracted
considerable
attention
as
potential
method
infections
early
tracking
course
diseases,
making
it
tool
global
public
health
professionals
fight
against
infectious
diseases.
This
review
first
provides
an
overview
biosensing
method,
including
principle
operation,
various
recognition
elements
biosensor
creation,
limitations
then
summarizes
notable
examples
pathogens,
focusing
on
microfluidic
magnetic
separation
techniques
pretreatment
samples.
The
explores
use
sensors
samples,
such
food,
wastewater,
biological
also
discusses
nanoparticles
sample
preparation
their
integration
into
devices
automated
highlights
importance
accurate
sensitive
diagnosis
need
point-of-care
approaches
simplify
reduce
cost
operation.
Biosensors and Bioelectronics,
Journal Year:
2024,
Volume and Issue:
250, P. 116079 - 116079
Published: Jan. 28, 2024
Following
the
global
COVID-19
pandemic
triggered
by
SARS-CoV-2,
need
for
rapid,
specific
and
cost-effective
point-of-care
diagnostic
solutions
remains
paramount.
Even
though
is
no
longer
a
public
health
emergency,
disease
still
poses
threat
leading
to
deaths,
it
continues
change
with
risk
of
new
variants
emerging
causing
surge
in
cases
deaths.
Here,
we
address
urgent
SARS-CoV-2.
We
propose
multiplexed
DNA-based
sensing
platform
that
utilizes
inkjet-printed
nanostructured
gold
electrodes
an
battery-free
near-field
communication
(NFC)
potentiostat
simultaneous
quantitative
detection
two
SARS-CoV-2
genes,
ORF1ab
N
gene.
The
strategy
based
on
formation
RNA-DNA
sandwich
structure
leads
highly
electrochemical
output.
providing
large
surface
area
enable
efficient
binding
increase
sensitivity.
NFC
enables
rapid
measurements
real-time
data
analysis
via
smartphone
application,
making
accessible
portable.
With
advantages
speed
(5
min),
simplicity,
sensitivity
(low
pM
range,
∼450%
signal
gain)
cost-effectiveness,
proposed
promising
alternative
diagnostics
high-throughput
complements
toolkit.
