Nanomaterials in the Wound Healing Process: New Insights and Advancements DOI Creative Commons
Tanikan Sangnim, Vivek Puri, Divya Dheer

et al.

Pharmaceutics, Journal Year: 2024, Volume and Issue: 16(3), P. 300 - 300

Published: Feb. 21, 2024

Wounds, which are becoming more common as a result of traumas, surgery, burns, and chronic illnesses like diabetes, remain critical medical problem. Infectious bacteria impact the healing process, particularly if its biofilm (biological films) leads to prolonged effect. Nanomaterials have emerged promising candidates in field wound due their unique properties versatile applications. New insights into interactions between nanomaterials microenvironments shed light on mechanisms underlying therapeutic effects. However, significantly minimal amount research has been carried out see these promote process. In this review, we provided an outline various types that studied for wounds infection prevention. Overall, utilization holds great promise continues evolve, providing new opportunities development effective efficient care therapies.

Language: Английский

Surface Wrinkling for Flexible and Stretchable Sensors DOI
Giwon Lee, Mohammad Zarei, Qingshan Wei

et al.

Small, Journal Year: 2022, Volume and Issue: 18(42)

Published: Sept. 1, 2022

Recent advances in nanolithography, miniaturization, and material science, along with developments wearable electronics, are pushing the frontiers of sensor technology into large-scale fabrication highly sensitive, flexible, stretchable, multimodal detection systems. Various strategies, including surface engineering, have been developed to control electrical mechanical characteristics sensors. In particular, wrinkling provides an effective alternative for improving both sensing performance deformability flexible stretchable sensors by releasing interfacial stress, preventing failure, enlarging areas. this study, recent strategies structures applications discussed. The fundamental mechanics, geometry various fabricating methods patterns summarized. Furthermore, current state approaches their impacts on development types sensors, strain, pressure, temperature, chemical, photodetectors, reviewed. Finally, existing approaches, designs, extrapolated future applications.

Language: Английский

Citations

110

Age of Flexible Electronics: Emerging Trends in Soft Multifunctional Sensors DOI Creative Commons

Jeng‐Hun Lee,

Kilwon Cho, Jang‐Kyo Kim

et al.

Advanced Materials, Journal Year: 2024, Volume and Issue: 36(16)

Published: Jan. 23, 2024

Abstract With the commercialization of first‐generation flexible mobiles and displays in late 2010s, humanity has stepped into age electronics. Inevitably, soft multifunctional sensors, as essential components next‐generation electronics, have attracted tremendous research interest like never before. This review is dedicated to offering an overview latest emerging trends sensors their accordant future development (R&D) directions for coming decade. First, key characteristics predominant target stimuli are highlighted. Second, important selection criteria introduced. Next, materials/structures identified. Specifically, R&D these envisaged based on trends, namely i) decoupling multiple stimuli, ii) data processing, iii) skin conformability, iv) energy sources. Finally, challenges potential opportunities discussed, new insights prospects fast‐emerging technology.

Language: Английский

Citations

91

Tough, Antifreezing, and Piezoelectric Organohydrogel as a Flexible Wearable Sensor for Human–Machine Interaction DOI
Yongdong Shi,

Youjun Guan,

Mingjie Liu

et al.

ACS Nano, Journal Year: 2024, Volume and Issue: 18(4), P. 3720 - 3732

Published: Jan. 18, 2024

Piezoelectric hydrogel sensors are becoming increasingly popular for wearable sensing applications due to their high sensitivity, self-powered performance, and simple preparation process. However, conventional piezoelectric hydrogels lack antifreezing properties thus confronted with the liability of rupture in low temperatures owing use water as dispersion medium. Herein, a kind organohydrogel that integrates piezoelectricity, low-temperature tolerance, mechanical robustness, stable electrical performance is reported by using poly(vinylidene fluoride) (PVDF), acrylonitrile (AN), acrylamide (AAm),

Language: Английский

Citations

73

Porous Conductive Textiles for Wearable Electronics DOI
Yichun Ding, Jinxing Jiang, Yingsi Wu

et al.

Chemical Reviews, Journal Year: 2024, Volume and Issue: 124(4), P. 1535 - 1648

Published: Feb. 19, 2024

Over the years, researchers have made significant strides in development of novel flexible/stretchable and conductive materials, enabling creation cutting-edge electronic devices for wearable applications. Among these, porous textiles (PCTs) emerged as an ideal material platform electronics, owing to their light weight, flexibility, permeability, wearing comfort. This Review aims present a comprehensive overview progress state art utilizing PCTs design fabrication wide variety integrated systems. To begin with, we elucidate how revolutionize form factors electronics. We then discuss preparation strategies PCTs, terms raw processes, key properties. Afterward, provide detailed illustrations are used basic building blocks fabricate intrinsically flexible or stretchable devices, including sensors, actuators, therapeutic energy-harvesting storage displays. further describe techniques systems either by hybridizing conventional off-the-shelf rigid components with integrating multiple fibrous PCTs. Subsequently, highlight some important application scenarios healthcare, sports training, converging technologies, professional specialists. At end Review, challenges perspectives on future research directions give overall conclusions. As demand more personalized interconnected continues grow, PCT-based wearables hold immense potential redefine landscape technology reshape way live, work, play.

Language: Английский

Citations

71

Highly piezoelectric, biodegradable, and flexible amino acid nanofibers for medical applications DOI Creative Commons
Meysam T. Chorsi, Thinh T. Le, Feng Lin

et al.

Science Advances, Journal Year: 2023, Volume and Issue: 9(24)

Published: June 14, 2023

Amino acid crystals are an attractive piezoelectric material as they have ultrahigh coefficient and appealing safety profile for medical implant applications. Unfortunately, solvent-cast films made from glycine brittle, quickly dissolve in body fluid, lack crystal orientation control, reducing the overall effect. Here, we present a processing strategy to create biodegradable, flexible, nanofibers of embedded inside polycaprolactone (PCL). The glycine-PCL nanofiber film exhibits stable performance with high ultrasound output 334 kPa [under 0.15 voltage root-mean-square (Vrms)], which outperforms state-of-the-art biodegradable transducers. We use this fabricate transducer facilitating delivery chemotherapeutic drug brain. device remarkably enhances animal survival time (twofold) mice-bearing orthotopic glioblastoma models. presented here could offer excellent platform not only therapy but also developing implantation fields.

Language: Английский

Citations

69

Solvent‐Free and Skin‐Like Supramolecular Ion‐Conductive Elastomers with Versatile Processability for Multifunctional Ionic Tattoos and On‐Skin Bioelectronics DOI Open Access

Wenwen Niu,

Qiong Tian, Zhiyuan Liu

et al.

Advanced Materials, Journal Year: 2023, Volume and Issue: 35(39)

Published: June 24, 2023

The development of stable and biocompatible soft ionic conductors, alternatives to hydrogels ionogels, will open up new avenues for the construction stretchable electronics. Here, a brand-new design, encapsulating naturally occurring ionizable compound by polymer via high-density hydrogen bonds, resulting in solvent-free supramolecular ion-conductive elastomer (SF-supra-ICE) that eliminates dehydration problem possesses excellent biocompatibility, is reported. SF-supra-ICE with high conductivity (>3.3 × 10-2 S m-1 ) exhibits skin-like softness strain-stiffening behaviors, elasticity, breathability, self-adhesiveness. Importantly, can be obtained simple water evaporation step solidify aqueous precursor into nature. Therefore, act as inks painted printed customized tattoos (I-tattoos) multifunctional on-skin bioelectronics. I-tattoos exhibit ultraconformal seamless contact human skin, enabling long-term high-fidelity recording various electrophysiological signals extraordinary immunity motion artifacts. Human-machine interactions are achieved exploiting transmit beings. Stretchable I-tattoo electrode arrays, manufactured printing method, demonstrated multichannel digital diagnosis health condition back muscles spine.

Language: Английский

Citations

67

Biodegradable ferroelectric molecular crystal with large piezoelectric response DOI
Han‐Yue Zhang, Yuan‐Yuan Tang, Zhuxiao Gu

et al.

Science, Journal Year: 2024, Volume and Issue: 383(6690), P. 1492 - 1498

Published: March 28, 2024

Transient implantable piezoelectric materials are desirable for biosensing, drug delivery, tissue regeneration, and antimicrobial tumor therapy. For use in the human body, they must show flexibility, biocompatibility, biodegradability. These requirements challenging conventional inorganic oxides polymers. We discovered high piezoelectricity a molecular crystal HOCH 2 (CF ) 3 CH OH [2,2,3,3,4,4-hexafluoropentane-1,5-diol (HFPD)] with large coefficient d 33 of ~138 picocoulombs per newton voltage constant g ~2450 × 10 −3 volt-meters under no poling conditions, which also exhibits good biocompatibility toward biological cells biodegradation biosafety physiological environments. HFPD can be composite polyvinyl alcohol to form flexible films 34.3 newton. Our material demonstrates ability crystals have attractive properties should interest applications transient electromechanical devices.

Language: Английский

Citations

67

Perspectives on recent advancements in energy harvesting, sensing and bio-medical applications of piezoelectric gels DOI Creative Commons
Thangavel Vijayakanth, Sudha Shankar, Gal Finkelstein-Zuta

et al.

Chemical Society Reviews, Journal Year: 2023, Volume and Issue: 52(17), P. 6191 - 6220

Published: Jan. 1, 2023

This review highlights the recent progress in piezoelectric gels (also known as PiezoGels) comprised of polymers, ceramic oxides and supramolecular materials used for energy harvesting, sensing wound dressing.

Language: Английский

Citations

66

Recent advances in thermal-conductive insulating polymer composites with various fillers DOI
Qingguo Chen, Kailun Yang, Yu Feng

et al.

Composites Part A Applied Science and Manufacturing, Journal Year: 2023, Volume and Issue: 178, P. 107998 - 107998

Published: Dec. 31, 2023

Language: Английский

Citations

63

Soft Sensors and Actuators for Wearable Human–Machine Interfaces DOI
Jonghwa Park, Youngoh Lee, Seungse Cho

et al.

Chemical Reviews, Journal Year: 2024, Volume and Issue: 124(4), P. 1464 - 1534

Published: Feb. 5, 2024

Haptic human-machine interfaces (HHMIs) combine tactile sensation and haptic feedback to allow humans interact closely with machines robots, providing immersive experiences convenient lifestyles. Significant progress has been made in developing wearable sensors that accurately detect physical electrophysiological stimuli improved softness, functionality, reliability, selectivity. In addition, soft actuating systems have developed provide high-quality by precisely controlling force, displacement, frequency, spatial resolution. this Review, we discuss the latest technological advances of actuators for demonstration HHMIs. We particularly focus on highlighting material structural approaches enable desired sensing properties necessary effective Furthermore, promising practical applications current HHMI technology various areas such as metaverse, robotics, user-interactive devices are discussed detail. Finally, Review further concludes discussing outlook next-generation technology.

Language: Английский

Citations

58