Journal of Colloid and Interface Science, Journal Year: 2025, Volume and Issue: 687, P. 801 - 816
Published: Feb. 17, 2025
Language: Английский
Advanced Functional Materials, Journal Year: 2024, Volume and Issue: 34(33)
Published: May 16, 2024
Abstract Piezocatalysts, because of their mechano‐electrical conversion properties, are exploited for various medical applications, such as sterilization, tissue engineering, biosensing, and disease theranostics. In particular, based on the unique advantage piezoelectric effect, piezocatalytic therapy (PCT) has been developed a novel promising candidate tumor therapy. To optimize utilization piezocatalysts in therapy, comprehensive understanding antitumor mechanism associated with these materials is imperative. Here, action principle elucidated by investigating piezocatalysts, reactants, energy inputs, products. Subsequently, mechanisms PCT have extensively discussed recapitulative follows: restraining cell proliferation, inducing programmed death, hindering metastasis, inhibiting angiogenesis, enhancing immunity. Additionally, optimized therapeutic outcomes PCT‐centric synergistic cancer systematically described. Finally, main challenges future research directions piezocatalysis applied envisioned. It believed that will serve new‐generation ingenious tool treatment.
Language: Английский
Citations
9
Advanced Functional Materials, Journal Year: 2024, Volume and Issue: 34(34)
Published: April 1, 2024
Abstract Electron spinning polarization has garnered increased attention for its potential to enhance device properties. However, application in life health, specifically anti‐infection and tissue repair, remains under‐explored. In this study, a ferromagnetic heterojunction CF (Fe 3 O 4 /TiO 2 ) is constructed with spin‐polarized electrons, demonstrating efficient antibiosis performance ultrasound (US) assistance. The antibacterial mechanism elucidated as follows: metallic states of Fe induce an asymmetric distribution the electron spin state TiO , increasing density electrons near Fermi level CF. Under US treatment, built‐in electric field synergistically suppress recombination sono‐activated carriers, promoting reactive oxygen species (ROS) production. Simultaneously, bacterial membrane influenced by micromagnetic induced causing severe disturbance respiratory chain. combined damage from ROS disturbed chain results death. Fortunately, built activates specific mechanosensitive ion channels, including TREK1, Piezo1, related pathways, enhancing osteoblast differentiation. Sonotherapy using exhibits excellent therapeutic effect treating osteomyelitis. This study provides novel insights into manipulating applications health.
Language: Английский
Citations
8
Journal of Nanobiotechnology, Journal Year: 2024, Volume and Issue: 22(1)
Published: April 12, 2024
Abstract Cancer stem cells (CSCs) represent both a key driving force and therapeutic target of tumoral carcinogenesis, tumor evolution, progression, recurrence. CSC-guided diagnosis, treatment, surveillance are strategically significant in improving cancer patients’ overall survival. Due to the heterogeneity plasticity CSCs, high sensitivity, specificity, outstanding targeting demanded for CSC detection targeting. Nanobiotechnologies, including biosensors, nano-probes, contrast enhancers, drug delivery systems, share identical features required. Implementing these techniques may facilitate performance In this review, we focus on some most recent advances how nanobiotechnologies leverage characteristics optimize diagnosis treatment liquid biopsy, clinical imaging, nano-treatment. Specifically, attributes maximize circulating DNA, cells, exosomes, improve positron emission computed tomography magnetic resonance enhance effects cytotoxic therapy, photodynamic immunotherapy radioimmunotherapy reviewed.
Language: Английский
Citations
8
Biomaterials, Journal Year: 2025, Volume and Issue: 317, P. 123109 - 123109
Published: Jan. 13, 2025
Language: Английский
Citations
1
Journal of Colloid and Interface Science, Journal Year: 2025, Volume and Issue: 687, P. 801 - 816
Published: Feb. 17, 2025
Language: Английский
Citations
1