Soft wearable electronics for evaluation of biological tissue mechanics DOI Open Access
Yifei Lu,

Lichao Ma,

Hehua Zhang

et al.

Soft Science, Journal Year: 2024, Volume and Issue: 4(4)

Published: Oct. 23, 2024

Flexible wearable devices designed to evaluate the biomechanical properties of deep tissues not only facilitate continuous and effective monitoring in basic performance but also exhibit significant potential broader disease assessments. Recent advancements are highlighted structural principled design platforms capable capturing various signals. These have led enhanced testing capabilities concerning spatial scales resolution modes at different depths. This review discusses engineering soft for evaluation tissue It encompasses measurement modes, device fabrication methods, integrated circuit (IC) integration schemes, characteristics depth accuracy. The core discussion focuses on platform development, targeting sites structure design, ranging from linear strain gauges conformal stretchable sensors complex three-dimensional (3D) circuit-integrated arrays. We further explore technologies associated with mechanisms designs, as well penetration these sensors. practical applications evident signals changes characteristics. results suggest that sensing systems hold substantial promise healthcare research.

Language: Английский

Ultrasound-Based Micro-/Nanosystems for Biomedical Applications DOI
Hui Huang,

Yi Zheng,

Meiqi Chang

et al.

Chemical Reviews, Journal Year: 2024, Volume and Issue: 124(13), P. 8307 - 8472

Published: June 26, 2024

Due to the intrinsic non-invasive nature, cost-effectiveness, high safety, and real-time capabilities, besides diagnostic imaging, ultrasound as a typical mechanical wave has been extensively developed physical tool for versatile biomedical applications. Especially, prosperity of nanotechnology nanomedicine invigorates landscape ultrasound-based medicine. The unprecedented surge in research enthusiasm dedicated efforts have led mass multifunctional micro-/nanosystems being applied biomedicine, facilitating precise diagnosis, effective treatment, personalized theranostics. deployment applications is rooted profound understanding relationship among composition, structure, property, bioactivity, application, performance. In this comprehensive review, we elaborate on general principles regarding design, synthesis, functionalization, optimization abundant particular, recent advancements imaging are meticulously summarized. Furthermore, systematically elucidate state-of-the-art studies concerning progress therapeutic targeting various pathological abnormalities including cancer, bacterial infection, brain diseases, cardiovascular metabolic diseases. Finally, conclude provide an outlook field with in-depth discussion challenges faced future developments further extensive clinical translation application.

Language: Английский

Citations

37
Artificial piezoelectric metamaterials DOI

Ziyan Gao,

Yu Lei,

Zhanmiao Li

et al.

Progress in Materials Science, Journal Year: 2025, Volume and Issue: unknown, P. 101434 - 101434

Published: Jan. 1, 2025

Citations

2
An implantable piezoelectric ultrasound stimulator (ImPULS) for deep brain activation DOI Creative Commons
Jason Hou, Md Osman Goni Nayeem,

Kian A. Caplan

et al.

Nature Communications, Journal Year: 2024, Volume and Issue: 15(1)

Published: June 4, 2024

Precise neurostimulation can revolutionize therapies for neurological disorders. Electrode-based stimulation devices face challenges in achieving precise and consistent targeting due to the immune response limited penetration of electrical fields. Ultrasound aid energy propagation, but transcranial ultrasound deep brain has spatial resolution caused by bone tissue scattering. Here, we report an implantable piezoelectric stimulator (ImPULS) that generates ultrasonic focal pressure 100 kPa modulate activity neurons. ImPULS is a fully-encapsulated, flexible micromachined transducer incorporates biocompatible piezoceramic, potassium sodium niobate [(K,Na)NbO

Language: Английский

Citations

16
Porous flexible molecular-based piezoelectric composite achieves milliwatt output power density DOI Creative Commons
Jia‐Qi Luo, Hai‐Feng Lu, Yijing Nie

et al.

Nature Communications, Journal Year: 2024, Volume and Issue: 15(1)

Published: Oct. 5, 2024

Molecular ferroelectrics have made breakthrough progress in intrinsic piezoelectric response that can be on par with advanced inorganic ceramics. However, their successful applications high-density energy harvesting and self-powered flexible devices been great challenge, owing to the low elastic moduli, intrinsically brittle, fracture proneness of such material systems under mechanical loading. Here, we developed a porous composite by using soft thermoplastic polyurethane (TPU) molecular ferroelectric materials. Benefiting from structure TPU, composites enable effectively large doping ratio (50%) [Me

Language: Английский

Citations

9
3D Printing and Biomedical Applications of Piezoelectric Composites: A Critical Review DOI
Suyun Li,

Yanbo Shan,

Jingyi Chen

et al.

Advanced Materials Technologies, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 13, 2024

Abstract Piezoelectric composites have received widespread attentions in the fields of biomedicine and vitro wearable devices due to their ability convert mechanical forces into charge signals. The preparation piezoelectric with complex structures through 3D printing technology can not only effectively improve output, but also enable customized therapeutic applications. This paper first introduces types reviews commonly used preparation, analyzing advantages disadvantages each technology. Then, state‐of‐the‐art biomedical applications composites, including drug sustained‐release, wound healing promotion, bone tissue cells growth promoting, neurorehabilitation stimulating, ultrasonic diagnosis, vivo biosensing sensing, are emphasized. Finally, main factors affecting printed outlooked, an in‐depth discussion on challenges toward analyzed. review is believed provide some fundamental knowledge composites.

Language: Английский

Citations

7
A wearable triboelectric impedance tomography system for noninvasive and dynamic imaging of biological tissues DOI Creative Commons
Peng Yang, Zhaoqi Liu,

Siyao Qin

et al.

Science Advances, Journal Year: 2024, Volume and Issue: 10(51)

Published: Dec. 20, 2024

Tissue imaging is usually captured by hospital-based nuclear magnetic resonance. Here, we present a wearable triboelectric impedance tomography (TIT) system for noninvasive of various biological tissues. The mechanism relies on the obtained information from different soft human A high-precision signal source designed basis composite nanogenerator, which exhibits minimal total harmonic distortion 0.03% and peak output signal-to-noise ratio up to 120 decibels. current density injected into skin around 79.58 milliamperes per square meter, far below safety threshold medical devices. TIT achieves time-resolved limbs’ tissues, many appealing functions can be realized using this system, including observation muscle movement, motion intention recognition, identification pathological changes tissue. Hence, with excellent biocompatibility integrated devices, such as medical-assistive exoskeletons smart protective suit.

Language: Английский

Citations

7
See how your body works in real time — wearable ultrasound is on its way DOI Creative Commons
Chonghe Wang,

Xuanhe Zhao

Nature, Journal Year: 2024, Volume and Issue: 630(8018), P. 817 - 819

Published: June 26, 2024

Full-body, continuous wearable ultrasound will benefit health care and biomedical research. Seven key obstacles must first be overcome.

Language: Английский

Citations

6
Decoding tissue biomechanics using conformable electronic devices DOI

Hyeokjun Yoon,

Jin‐Hoon Kim,

David Sadat

et al.

Nature Reviews Materials, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 21, 2024

Language: Английский

Citations

5
Enhancing Ultrasound Power Transfer: Efficiency, Acoustics, and Future Directions DOI Creative Commons
Yi Zheng, Zhuomin Zhang, Yanhu Zhang

et al.

Advanced Materials, Journal Year: 2024, Volume and Issue: unknown

Published: July 23, 2024

Abstract Implantable medical devices (IMDs), like pacemakers regulating heart rhythm or deep brain stimulators treating neurological disorders, revolutionize healthcare. However, limited battery life necessitates frequent surgeries for replacements. Ultrasound power transfer (UPT) emerges as a promising solution sustainable IMD operation. Current research prioritizes implantable materials, with less emphasis on sound field analysis and maximizing energy during wireless delivery. This review addresses this gap. A comprehensive of UPT technology, examining cutting‐edge system designs, particularly in supply efficiency is provided. The critically examines existing models, summarizing the key parameters influencing transmission systems. For first time, an flow diagram general proposed to offer insights into overall functioning. Additionally, explores development stages showcasing representative designs applications. remaining challenges, future directions, exciting opportunities associated are discussed. By highlighting importance IMDs advanced functions biosensing closed‐loop drug delivery, well UPT's potential, aims inspire further advancements field.

Language: Английский

Citations

4
Sustainable Biopolymers in Eco‐Friendly Triboelectric Energy Harvesting DOI Creative Commons
Zekun Li, Aifang Yu, Junyi Zhai

et al.

Advanced Materials, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 6, 2024

Abstract Biopolymer‐based triboelectric nanogenerators (B‐TENGs) represent an innovative fusion of eco‐friendly, sustainable energy‐harvesting technology with renewable and environmentally benign biopolymer material. This integration not only introduces novel pathways for advancing green energy solutions but also offers a critical approach to addressing contemporary environmental challenges fostering progress. Over the past few years, B‐TENGs have seen rapid remarkable growth in realm biopolymers, device architecture, their applications (e.g., implantable power source, electronic medicine, human anatomical physiological movements monitoring sensors, etc.). In this review article, promising developments harnessing biopolymers are encapsulated, enumerate representative applications, evaluate pros cons these highlight key future research, offer strategic recommendations innovating realizing advanced B‐TENGs.

Language: Английский

Citations

4