Microsystems & Nanoengineering,
Journal Year:
2024,
Volume and Issue:
10(1)
Published: June 25, 2024
Abstract
During
cardiac
development,
mechanotransduction
from
the
in
vivo
microenvironment
modulates
cardiomyocyte
growth
terms
of
number,
area,
and
arrangement
heterogeneity.
However,
response
cells
to
different
degrees
mechanical
stimuli
is
unclear.
Organ-on-a-chip,
as
a
platform
for
investigating
stress
cellular
mimicry
microenvironment,
limited
by
lack
ability
accurately
quantify
externally
induced
stimuli.
previous
technology
lacks
integration
external
feedback
sensors
microfluidic
platforms
obtain
apply
precise
amounts
Here,
we
designed
cell
stretching
with
an
in-situ
sensor.
The
liquid
metal
can
measure
stimulation
caused
deformation
vacuum
cavity
exerted
on
cells.
was
applied
human
cardiomyocytes
(AC16)
under
cyclic
strain
(5%,
10%,
15%,
20
25%),
found
that
promoted
membrane
gradually
unify,
stabilized
at
15%
amplitude,
which
even
more
effective
after
3
days
culture.
platform’s
control
measurement
forces
be
used
establish
accurate
vitro
microenvironmental
models
disease
modeling
therapeutic
research.
Small,
Journal Year:
2024,
Volume and Issue:
20(26)
Published: March 14, 2024
Abstract
Single‐cell
mass
spectrometry
(MS)
is
significant
in
biochemical
analysis
and
holds
great
potential
biomedical
applications.
Efficient
sample
preparation
like
sorting
(i.e.,
separating
target
cells
from
the
mixed
population)
desalting
moving
off
non‐volatile
salt
solution)
urgently
required
single‐cell
MS.
However,
traditional
methods
suffer
complicated
operation
with
various
apparatus,
or
insufficient
performance.
Herein,
a
one‐step
strategy
by
leveraging
label‐free
impedance
flow
cytometry
(IFC)
based
microfluidics
proposed.
Specifically,
IFC
framework
to
characterize
sort
single‐cells
adopted.
Simultaneously
sorting,
cell
transferred
local
high‐salinity
buffer
MS‐compatible
solution.
In
this
way,
are
achieved
collected
can
be
directly
fed
for
MS
analysis.
A
high
efficiency
(>99%),
cancer
purity
(≈87%),
whole
workflow
of
impedance‐based
separation
normal
(MCF‐10A)
(MDA‐MB‐468)
verified.
As
standalone
module,
microfluidic
chip
compatible
variety
methods,
envisioned
provide
new
paradigm
efficient
preparation,
further
multi‐modal
electrical
metabolic)
characterization
single‐cells.
Mechanics of Advanced Materials and Structures,
Journal Year:
2024,
Volume and Issue:
unknown, P. 1 - 16
Published: Aug. 4, 2024
Bending
responses
of
a
nanocomposite-reinforced
cylindrical
panel
are
studied
in
this
article.
A
shell
is
assumed
micro
scale
and
sandwiched
by
piezoelectric
layers.
In
article,
micro-size
dependent
theory
named
as
the
modified
couple
stress
(MCST)
analytically
employed
kinematic
relations
extended
through
employing
shear
deformable
model
order
to
investigate
electroelastic
bending
three-layered
micro-shell
bonded
between
smart
layers
subjected
an
applied
voltage,
external
internal
pressures.
The
rested
on
two
parametrically
elastic
foundation.
develop
constitutive
relations,
mixture's
rule
well
Halpin-Tsai
utilized
compute
governing
equations.
Electroelastostatic
obtained
trigonometric
functions.
large
parametric
analysis
presented
explore
deflection
with
change
thickness
layer
radius,
length
radius
ratio,
different
characteristics
nanoplatelet
reinforcement
for
both
pressure.
proposed
composite
electromechanical
structure
may
be
used
structures
systems.
controllable
system
can
suggested
usage
graphene
nanoplatelets
because
flexibility
affecting
parameters.
Scientific Reports,
Journal Year:
2024,
Volume and Issue:
14(1)
Published: Nov. 28, 2024
The
nanoscale
spinel
structured
ferrites
co-doped
with
multi-valence
ions
are
of
great
interest
and
proving
to
be
promising
for
numerous
applications.
In
light
this,
herein
we
report
tetravalent
titanium
(Ti4+)
divalent
zinc
(Zn2+)
nickel
generic
formula
NiFe2
−
2xTixZnxO4
(x
=
0.00
≤
x
0.20
in
step
0.05).
sol
gel
self
combustion
method
assistance
citric
acid
as
fuel
was
employed
prepare
the
samples.
X-ray
diffraction
(XRD)
analysis
Rietveld
refinement
performed
confirm
single-phase
cubic
structure.
sphere
type
grain
morphology
samples
revealed
by
SEM
images.
compositional
studies
carried
out
EDAX
showed
desired
formation
composition
absence
impurities
characteristics
bands
belonging
were
appeared
IR
spectra
confirming
successive
sample
forming.
different
surface
parameters
including
area
pore
volume
estimated
using
Brunauer-Emmett-Teller
(BET)
analysis.
low
coercive
nature
soft
magnetism
observed
co-doping
M-H
plots.
electric
dielectric
decrementing
behaviour
increment
Ti4+-Zn2+
co-doping.
This
study
outcome
signifies
that
could
a
prominent
many
nanoelectronics
Advanced Functional Materials,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 14, 2025
Abstract
Room‐temperature
liquid
metals
(RTLMs)
exhibit
inherent
fluidity,
metallic
conductivity,
remarkable
stability,
and
recyclability,
which
indicate
significant
potential
for
applications
in
improving
the
efficiency
of
electronics
recycling
reducing
costs.
However,
low
viscosity
RTLMs
their
poor
interfacial
adhesion
to
substrates
typically
necessitate
utilization
intricate
fabrication
processes.
Here,
a
viscosity‐tunable,
photothermal
repairable,
full‐component
recyclable
eutectic
gallium–indium/epoxy‐modified
lignin/polyethylene
glycol
diacid/ethylene
vitrimer
(EGaIn‐LPEv)
is
presented
printed
circuits.
The
system
displays
good
stability
tunable
at
room
temperature
because
ultra‐high
reactive
site
content
modified
lignin
dual
dynamic
bonding
by
introduction
ethylene
glycol.
EGaIn‐LPEv‐based
circuit
exhibits
high
resolution
full
component
recovery
up
7.6
µm
98.3
wt.%,
respectively.
As
principal
component,
not
only
enhances
system's
green
credentials
but
also
endows
it
with
an
efficient
repairable
capability.
reconnection
damaged
can
be
achieved
15
s
through
808
nm
infrared
activation.
This
study
opens
new
avenue
development
manufacturing
processes
sustainable
application
advanced,
high‐resolution,
fully
recycled
electronic
devices.